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PORTABLE AND FAST SURFACE PLASMON RESONANCE POINT-OF-CARE TEST FOR COVID-19

Objective

The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has led to more than 7.031.249 cases and 403.112 deaths globally as of June 8, 2020. Although most infections are self-limited, about 15% of infected adults develop severe pneumonia that requires treatment with supplemental oxygen and an additional 5% progress to critical illness with hypoxaemic respiratory failure, acute respiratory distress syndrome, and multiorgan failure that necessitates ventilatory support, often for several weeks.
Worldwide, infections and death from SAR-CoV-2 continue during June with more than 110.000 new cases every day despite lockdown in Europe and oversees. What started as a temporary sanitary issue, has morphed into a more permanent and long-lasting pan epidemic outbreak. One efficient manner to limit COVID-19 spreading and an adequate mean of better managing the COVID-19 outbreak is through unrestrained availability of fast, efficient, accurate and cost-effective point-of-care tests (POCT). Here we propose C-POCT-S, a rapid (<30 min), sensitive (200 vps/mL), selective (SARS-CoV-2), and inexpensive ( < 20 Euros) solution to address this medical need. C-POCT-S is based on a combination of several technologies such as the use of COVID-19 specific nanobodies (VHH), magnetic nanoparticles with high magnetic strength and a VHH modified interfaces, all integrated in a a hand-held surface plasmon resonance (SPR) based POC test (C-POCT-S) for the screening of the presence/absence of the SARS-CoV-2 virus in nasal and salvia samples.
The aim of this project is to complete product optimization, performance validation in a clinical setting and manufacturing quality control for C-POCT-S and completion of its technical file, to enable declaration of conformity and affixing of CE mark.

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Keywords

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IA - Innovation action

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Call for proposal

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(opens in new window) H2020-SC1-PHE-CORONAVIRUS-2020-2

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Coordinator

UNIVERSITE DE LILLE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 344 751,04
Address
42 RUE PAUL DUEZ
59000 Lille
France

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Region
Hauts-de-France Nord-Pas de Calais Nord
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 344 751,04

Participants (7)

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