Description du projet
Une nouvelle solution portable pour les ressources limitées des USI
Les systèmes de soins de santé du monde entier ont été submergés par l’accroissement important du nombre de patients atteints de la COVID‑19 et nécessitant une admission en unité de soins intensifs (USI). Tandis que les taux exacts diffèrent selon les États membres de l’UE, entre 3 et 12 % de la population infectée nécessite une ventilation mécanique. La personnalisation du traitement permettra de rationner de manière plus ciblée les ressources limitées des USI. Dans cette optique, le projet VASCOVID, financé par l’UE, développe une plateforme de surveillance de la santé en temps réel, portable et non invasive, combinant la spectroscopie dans le proche infrarouge à résolution temporelle et la spectroscopie à corrélation diffuse. Cette solution permettra de tester à grande échelle de nouvelles procédures de traitement et de nouvelles thérapies, ciblant les déficiences microvasculaires. En outre, elle réduira l’incidence des échecs d’extubation (réintubation dans les sept jours) dans les USI.
Objectif
As COVID-19 spreads worldwide, the surge in patients requiring intensive care unit (ICU) admission has been overwhelming to the healthcare systems. Critical care triage to allow the rationing of scarce ICU resources is needed but is hindered due to lack of personalization. The management of acute respiratory failure and hemodynamics is critical at the ICU. In fact, of the seven million COVID-19 cases (end of May 2020) 3-12% required mechanical ventilation which forms the primary target of VASCOVID where we focus on; (1) patient stratification derived from endothelial function evaluation, and, (2) evaluation of cardiopulmonary interactions that personalizes conservative ventilation strategies in order to avoid ventilator-induced lung injury and readiness to wean from the ventilator. VASCOVID will deploy and mature our portable, non-invasive and real-time health monitoring platform for this purpose. This platform combines two bio-photonics technologies, time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy, and is the fruit of long-term collaboration between core project partners in two European projects (BabyLux and LUCA) where high technology readiness level have been achieved for neuro-monitoring and thyroid cancer screening. VASCOVID will adapt the platform to meet the needs of a typical ICU dealing with COVID-19 and other patients requiring ventilation, as well as to leverage large-scale testing of new treatment procedures and therapies aimed to address microvascular impairment and to reduce extubation failure on ICU patients weaning out of mechanical ventilation life-support. The platform is easy to deploy, cost-effective and provides real-time fast results and its transition to clinical practice will be eased through this project by pushing CE certification. Our inter-disciplinary consortium is well-suited for these activities and will interact closely with our on-going clinical study spanning four countries and a dozen hospitals.
Champ scientifique
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturefruit growing
- medical and health sciencesclinical medicinecritical care medicine
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesclinical medicineoncology
- natural sciencesphysical sciencesopticsspectroscopy
Mots‑clés
Programme(s)
Appel à propositions
H2020-SC1-PHE-CORONAVIRUS-2020-2
Voir d’autres projets de cet appelSous appel
H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT
Régime de financement
IA - Innovation actionCoordinateur
08860 Castelldefels
Espagne