Project description
New portable solution for scarce ICU resources
Healthcare systems around the world have been overwhelmed by the surge in seriously ill COVID-19 patients who require intensive care unit (ICU) admission. While exact rates differ per EU Member State, 3–12 % of the infected population need mechanical ventilation. The personalisation of treatment will allow for the more targeted rationing of scarce ICU resources. With this in mind, the EU-funded VASCOVID project is developing a portable, non-invasive and real-time health monitoring platform that combines time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy. The solution will enable the large-scale testing of new treatment procedures and therapies, targeting microvascular impairment. Moreover, it will reduce the incidence of extubation failure (reintubation within seven days) in ICUs.
Objective
As COVID-19 spreads worldwide, the surge in patients requiring intensive care unit (ICU) admission has been overwhelming to the healthcare systems. Critical care triage to allow the rationing of scarce ICU resources is needed but is hindered due to lack of personalization. The management of acute respiratory failure and hemodynamics is critical at the ICU. In fact, of the seven million COVID-19 cases (end of May 2020) 3-12% required mechanical ventilation which forms the primary target of VASCOVID where we focus on; (1) patient stratification derived from endothelial function evaluation, and, (2) evaluation of cardiopulmonary interactions that personalizes conservative ventilation strategies in order to avoid ventilator-induced lung injury and readiness to wean from the ventilator. VASCOVID will deploy and mature our portable, non-invasive and real-time health monitoring platform for this purpose. This platform combines two bio-photonics technologies, time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy, and is the fruit of long-term collaboration between core project partners in two European projects (BabyLux and LUCA) where high technology readiness level have been achieved for neuro-monitoring and thyroid cancer screening. VASCOVID will adapt the platform to meet the needs of a typical ICU dealing with COVID-19 and other patients requiring ventilation, as well as to leverage large-scale testing of new treatment procedures and therapies aimed to address microvascular impairment and to reduce extubation failure on ICU patients weaning out of mechanical ventilation life-support. The platform is easy to deploy, cost-effective and provides real-time fast results and its transition to clinical practice will be eased through this project by pushing CE certification. Our inter-disciplinary consortium is well-suited for these activities and will interact closely with our on-going clinical study spanning four countries and a dozen hospitals.
Fields of science
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturefruit growing
- medical and health sciencesclinical medicinecritical care medicine
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesclinical medicineoncology
- natural sciencesphysical sciencesopticsspectroscopy
Keywords
Programme(s)
Call for proposal
H2020-SC1-PHE-CORONAVIRUS-2020-2
See other projects for this callSub call
H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT
Funding Scheme
IA - Innovation actionCoordinator
08860 Castelldefels
Spain