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Pancreatic cancer AI for genomics and personalized Medicine

Objective

The central PANCAIM concept is to successfully exploit available genomic and clinical data to improve personalized medicine of pancreatic cancer. PANCAIM’s concept is unique as it integrates the whole spectrum of genomics with radiomics and pathomics, the three future pillars of personalized medicine. The integration of these three modalities is very challenging in the clinic, but also with AI. PANCAIM uses an explainable, data-efficient, two-staged AI approach. AI biomarkers transform the unimodal data domains into interpretable likelihoods of intermediate disease features. A second AI layer merges the biomarkers and responds with an integrated assessment of prognosis, prediction and monitoring of therapy response, to assist in clinical decision making.
PANCAIM builds on four key concepts of AI in Healthcare: data providers, clinical expertise, AI developers, and MedTech companies to connect to data and bring AI to healthcare. Data quantity and quality is the main factor for successful AI. Partners provide eleven Pan European repositories of almost 6000 patients that are open to ongoing accrual. SME Collective Minds builds the GDPR data platform that hosts the data and provides a trustable connection to healthcare for even more and sustainable data. SME TheHyve builds tooling to connect to more genomic repositories (EOSC Health). Six Pan European academic centers provide clinical expertise across all modalities and help realize a curated, high quality annotated data set. Partners also include expert AI healthcare researchers across all clinical modalities with a proven track record. Finally, Siemens Healthineers provides their AI expertise and tooling to bring AI into healthcare for clinical validation and swift clinical integration in 3000 health care institutes.

Field of science

  • /medical and health sciences/clinical medicine/cancer/pancreatic cancer

Call for proposal

H2020-SC1-FA-DTS-2020-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

STICHTING KATHOLIEKE UNIVERSITEIT
Address
Geert Grooteplein Noord 9
6525 EZ Nijmegen
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 425 000

Participants (8)

KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 1 008 750
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
OSLO UNIVERSITETSSYKEHUS HF
Norway
EU contribution
€ 1 184 375
Address
Kirkeveien 166 Tarnbygget
0450 Oslo
Activity type
Higher or Secondary Education Establishments
FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III
Spain
EU contribution
€ 786 650
Address
Calle Melchor Fernandez Almagro 3
28029 Madrid
Activity type
Research Organisations
UNIVERSITY OF GLASGOW
United Kingdom
EU contribution
€ 1 018 728,75
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments
COLLECTIVE MINDS RADIOLOGY AB
Sweden
EU contribution
€ 1 336 000
Address
Hornakersvagen 14
183 65 Taby
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SIEMENS HEALTHCARE GMBH
Germany
EU contribution
€ 800 000
Address
Henkestrasse 127
91052 Erlangen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE HYVE BV
Netherlands
EU contribution
€ 380 625
Address
Arthur Van Schendelstraat 650
3511 MJ Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AMIRES SRO
Czechia
EU contribution
€ 296 250
Address
Stavitelska 1099/6
160 00 Praha 6
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)