Digital twins for model-driven non-invasive electrical brain stimulation

Información del proyecto

Neurotwin

Identificador del acuerdo de subvención: 101017716

DOI 10.3030/101017716

Fecha de la firma de la CE 2 Diciembre 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 30 Junio 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coste total € 4 485 736,25

Aportación de la UE € 4 485 735,00

Coordinado por

NEUROELECTRICS BARCELONA SL
Spain

Resultado final

Documents, reports (2)

Web and dissemination materials

Website project logo and dissemination materials

Cross-project collaboration plan

Updated each reporting period

Publicaciones

Peer reviewed articles (5)

Complex spatiotemporal oscillations emerge from transverse instabilities in large-scale brain networks

Autores: Pau Clusella; Gustavo Deco; Morten L. Kringelbach; Giulio Ruffini; Jordi Garcia-Ojalvo
Publicado en: PLOS Computational Biology, 2023, ISSN 1553-7358
Editor: PLOS
DOI: 10.1371/journal.pcbi.1010781

Comparison between an exact and a heuristic neural mass model with second-order synapses

Autores: Pau Clusella, Elif Köksal-Ersöz, Jordi Garcia-Ojalvo and Giulio Ruffini
Publicado en: Biological Cybernetics, 2022, ISSN 0340-1200
Editor: Springer Verlag
DOI: 10.1007/s00422-022-00952-7

LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics

Autores: Giulio Ruffini,Giada Damiani, Diego Lozano-Soldevilla, Nikolas Deco, Fernando E. Rosas, Narsis A. Kiani, Adrián Ponce-Alvarez, Morten L. Kringelbach, Robin Carhart-Harris, Gustavo Deco
Publicado en: Plos Computational Biology, 2023, ISSN 1553-7358
Editor: PLOS
DOI: 10.1371/journal.pcbi.1010811

Dynamic sensitivity analysis: Defining personalised strategies to drive brain state transitions via whole brain modelling

Autores: Jakub Vohryzek, Joana Cabral, Francesca Castaldo, Yonatan Sanz-Perl, Louis-David Lord, Henrique M. Fernandes, Vladimir Litvak, Morten L. Kringelbach, Gustavo Deco
Publicado en: Computational and Structural Biotechnology Journal, 2023, ISSN 2001-0370
Editor: Elsevier
DOI: 10.1016/j.csbj.2022.11.060

A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings

Autores: Roser Sanchez-Todo; André M. Bastos; Edmundo Lopez Sola; Borja Mercadal; Emiliano Santarnecchi; Earl K. Miller; Gustavo Deco; Giulio Ruffini
Publicado en: NeuroImage, 2023, ISSN 1053-8119
Editor: Academic Press
DOI: 10.1016/j.neuroimage.2023.119938

Other (7)

Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice

Autores: Carlos Andrés Sánchez-León, Guillermo Sánchez-Garrido Campos, Marta Fernández, Álvaro Sánchez-López, Javier F Medina, Javier Márquez-Ruiz
Publicado en: 2023
Editor: bioRxiv
DOI: 10.1101/2023.02.18.529047

Spherical harmonics representation of the steady-state membrane potential shift induced by tDCS in realistic neuron models

Autores: Adrià Galan-Gadea, Ricardo Salvador, Fabrice Bartolomei, Fabrice Wendling, Giulio Ruffini
Publicado en: 2022
Editor: bioRxiv
DOI: 10.1101/2022.07.19.500653

Analysis and extension of exact mean-field theory with dynamic synaptic currents

Autores: Giulio Ruffini
Publicado en: 2022
Editor: bioRxiv
DOI: 10.1101/2021.09.01.458563

Regular and sparse neuronal synchronization are described by identical mean field dynamics

Autores: Clusella, Pau; Montbrió, Ernest
Publicado en: 2022
Editor: arxiv
DOI: 10.48550/arxiv.2208.05515

The 2D Ising model, criticality and AIT

Autores: Giulio Ruffini and Gustavo Deco
Publicado en: 2021
Editor: bioRxiv
DOI: 10.1101/2021.10.21.465265

Kuramoto model for populations of quadratic integrate-and-fire neurons with chemical and electrical coupling

Autores: Pau Clusella; Bastian Pietras; Ernest Montbrió
Publicado en: 2021
Editor: arxiv
DOI: 10.48550/arxiv.2110.07665

Design of effective personalised perturbation strategies for enhancing cognitive intervention in Alzheimer’s disease

Autores: Jakub Vohryzek, Joana Cabral, Yonatan Sanz Perl, Murat Demirtas, Carles Falcon, Juan Domingo Gispert, Beatriz Bosch, Mircea Balasa, Morten Kringelbach, Raquel Sanchez-Valle, Giulio Ruffini, Gustavo Deco
Publicado en: 2023
Editor: bioRxiv
DOI: 10.1101/2023.04.20.537688

Thesis and dissertations (1)

Validation and Refinement of a Laminar Neural Mass Model Using in vivo Mice Data

Autores: Martina Moreno Fina, Pau Clusella Coberó, Roser Sánchez-Todo, and Jordi Soriano Fradera
Publicado en: 2023
Editor: Universitat Politecnica de Catalunya

Conference proceedings (1)

TH-230. Mechanistic understanding of Alzheimer’s disease through hybrid brain models: from mesoscale to macroscale, and design of personalized stimulation protocols

Autores: R Sanchez-Todo, EL Sola, R Salvador, MC Biagi, G Deco, G Ruffini
Publicado en: 2022
Editor: Clinical Neurophysiology
DOI: 10.1016/j.clinph.2022.07.416