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Digital twins for model-driven non-invasive electrical brain stimulation

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Publications

Perturbing whole‐brain models of brain hierarchy: An application for depression following pharmacological treatment (opens in new window)

Author(s): Marcel Socoró‐Garrigosa, Yonatan Sanz Perl, Morten L. Kringelbach, David Erritzoe, David J. Nutt, Robin Carhart‐Harris, Jakub Vohryzek, Gustavo Deco
Published in: Annals of the New York Academy of Sciences, 2025, ISSN 0077-8923
Publisher: New York Academy of Sciences
DOI: 10.1111/nyas.15391

Metastable oscillatory modes emerge from synchronization in the brain spacetime connectome (opens in new window)

Author(s): Joana Cabral, Francesca Castaldo, Jakub Vohryzek, Vladimir Litvak, Christian Bick, Renaud Lambiotte, Karl Friston, Morten L. Kringelbach, Gustavo Deco
Published in: Communications Physics, Issue 5, 2023, ISSN 2399-3650
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42005-022-00950-y

A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement (opens in new window)

Author(s): Hamed Ekhtiari, Peyman Ghobadi-Azbari, Axel Thielscher, Andrea Antal, Lucia M. Li, A. Duke Shereen, Yuranny Cabral-Calderin, Daniel Keeser, Til Ole Bergmann, Asif Jamil, Ines R. Violante, Jorge Almeida, Marcus Meinzer, Hartwig R. Siebner, Adam J. Woods, Charlotte J. Stagg, Rany Abend, Daria Antonenko, Tibor Auer, Marc Bächinger, Chris Baeken, Helen C. Barron, Henry W. Chase, Jenny Crinion, Abhish
Published in: Nature Protocols, Issue 17, 2022, Page(s) 596-617, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-021-00664-5

Modeling the impact of neuromorphological alterations in Down syndrome on fast neural oscillations (opens in new window)

Author(s): Pau Clusella, Linus Manubens-Gil, Jordi Garcia-Ojalvo, Mara Dierssen
Published in: PLOS Computational Biology, 2024, ISSN 1553-7358
Publisher: Public Library of Science (PLOS)
DOI: 10.1101/2024.01.13.575481

Neural Geometrodynamics, Complexity, and Plasticity: A Psychedelics Perspective (opens in new window)

Author(s): Giulio Ruffini, Edmundo Lopez-Sola, Jakub Vohryzek, Roser Sanchez-Todo
Published in: Entropy, Issue 26, 2024, Page(s) 90, ISSN 1099-4300
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/e26010090

Cognitive and Neuropathophysiological Outcomes of Gamma-tACS in Dementia: A Systematic Review (opens in new window)

Author(s): Valerio Manippa, Annalisa Palmisano, Michael A. Nitsche, Marco Filardi, Davide Vilella, Giancarlo Logroscino, Davide Rivolta
Published in: Neuropsychology Review, Issue 34, 2024, Page(s) 338-361, ISSN 1040-7308
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11065-023-09589-0

Complex spatiotemporal oscillations emerge from transverse instabilities in large-scale brain networks (opens in new window)

Author(s): Pau Clusella; Gustavo Deco; Morten L. Kringelbach; Giulio Ruffini; Jordi Garcia-Ojalvo
Published in: PLOS Computational Biology, 2023, ISSN 1553-7358
Publisher: PLOS
DOI: 10.1371/journal.pcbi.1010781

Brain dynamics predictive of response to psilocybin for treatment-resistant depression (opens in new window)

Author(s): Jakub Vohryzek, Joana Cabral, Louis-David Lord, Henrique Fernandes, Leor Roseman, David Nutt, Robin Carhart-Harris, Gustavo Deco, Morten Kringelbach
Published in: Brain Communications, 2024, ISSN 2632-1297
Publisher: Oxford University Press (OUP)
DOI: 10.21203/rs.3.rs-2060381/v1

Structured Dynamics in the Algorithmic Agent (opens in new window)

Author(s): Giulio Ruffini, Francesca Castaldo, Jakub Vohryzek
Published in: Entropy, Issue 27, 2025, Page(s) 90, ISSN 1099-4300
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/e27010090

Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice (opens in new window)

Author(s): Carlos A Sánchez-León, Guillermo Sánchez-Garrido Campos, Marta Fernández, Álvaro Sánchez-López, Javier F Medina, Javier Márquez-Ruiz
Published in: eLife, Issue 13, 2025, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.100941.3

Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models (opens in new window)

Author(s): Marta Estévez-Rodríguez, Guillermo Sánchez-Garrido Campos, Ángela M. Zafra, Isabel Cordones, Javier Márquez-Ruiz
Published in: Frontiers in Neuroscience, Issue 19, 2025, ISSN 1662-453X
Publisher: Frontiers Media SA
DOI: 10.3389/fnins.2025.1609679

Preclinical insights into gamma-tACS: foundations for clinical translation in neurodegenerative diseases (opens in new window)

Author(s): Guillermo Sánchez-Garrido Campos, Ángela M. Zafra, Marta Estévez-Rodríguez, Isabel Cordones, Giulio Ruffini, Javier Márquez-Ruiz
Published in: Frontiers in Neuroscience, Issue 19, 2025, ISSN 1662-453X
Publisher: Frontiers Media SA
DOI: 10.3389/fnins.2025.1549230

Preliminary Evidence for Perturbation‐Based tACS‐EEG Biomarkers of Gamma Activity in Alzheimer's Disease (opens in new window)

Author(s): Annalisa Palmisano, Luke R. Pezanko, Davide Cappon, Elisa Tatti, Joanna Macone, Giacomo Koch, Carmelo L. Smeralda, Sara M. Romanella, Giulio Ruffini, Davide Rivolta, Daniel Z. Press, Alvaro Pascual‐Leone, Georges El‐Fakhri, Emiliano Santarnecchi
Published in: International Journal of Geriatric Psychiatry, Issue 40, 2025, ISSN 0885-6230
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/gps.70025

The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation (opens in new window)

Author(s): Edmund T. Rolls, Sylvia Wirth, Gustavo Deco, Chu‐Chung Huang, Jianfeng Feng
Published in: Human Brain Mapping, Issue 44, 2023, Page(s) 629-655, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.26089

Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness (opens in new window)

Author(s): Yonatan Sanz Perl, Carla Pallavicini, Ignacio Pérez Ipiña, Athena Demertzi, Vincent Bonhomme, Charlotte Martial, Rajanikant Panda, Jitka Annen, Agustin Ibañez, Morten Kringelbach, Gustavo Deco, Helmut Laufs, Jacobo Sitt, Steven Laureys, Enzo Tagliazucchi
Published in: PLOS Computational Biology, Issue 17, 2021, Page(s) e1009139, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pcbi.1009139

Exact low-dimensional description for fast neural oscillations with low firing rates (opens in new window)

Author(s): Pau Clusella and Ernest Montbrió
Published in: Physical Review E, Issue 109, 2024, ISSN 2470-0053
Publisher: American Physical Society (APS)
DOI: 10.48550/arxiv.2208.05515

The human posterior parietal cortex: effective connectome, and its relation to function (opens in new window)

Author(s): Edmund T Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Feng
Published in: Cerebral Cortex, Issue 33, 2023, Page(s) 3142-3170, ISSN 1047-3211
Publisher: Oxford University Press
DOI: 10.1093/cercor/bhac266

Human brain dynamics are shaped by rare long-range connections over and above cortical geometry (opens in new window)

Author(s): Jakub Vohryzek, Yonatan Sanz-Perl, Morten L. Kringelbach, Gustavo Deco
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2415102122

The flattening of spacetime hierarchy of the <i>N,N</i>-dimethyltryptamine brain state is characterized by harmonic decomposition of spacetime (HADES) framework (opens in new window)

Author(s): Jakub Vohryzek, Joana Cabral, Christopher Timmermann, Selen Atasoy, Leor Roseman, David J Nutt, Robin L Carhart-Harris, Gustavo Deco, Morten L Kringelbach
Published in: National Science Review, Issue 11, 2024, ISSN 2095-5138
Publisher: Oxford University Press (OUP)
DOI: 10.1093/nsr/nwae124

Selective Brain Activations and Connectivities Related to the Storage and Recall of Human Object‐Location, Reward‐Location, and Word‐Pair Episodic Memories (opens in new window)

Author(s): Edmund T. Rolls, Ruohan Zhang, Gustavo Deco, Deniz Vatansever, Jianfeng Feng
Published in: Human Brain Mapping, Issue 45, 2024, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.70056

Comparison between an exact and a heuristic neural mass model with second-order synapses (opens in new window)

Author(s): Pau Clusella, Elif Köksal-Ersöz, Jordi Garcia-Ojalvo and Giulio Ruffini
Published in: Biological Cybernetics, 2022, ISSN 0340-1200
Publisher: Springer Verlag
DOI: 10.1007/s00422-022-00952-7

Multi-modal and multi-model interrogation of large-scale functional brain networks (opens in new window)

Author(s): Francesca Castaldo, Francisco Páscoa dos Santos, Ryan C Timms, Joana Cabral, Jakub Vohryzek, Gustavo Deco, Mark Woolrich, Karl Friston, Paul Verschure, Vladimir Litvak
Published in: NeuroImage, Issue 277, 2024, Page(s) 120236, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.120236

Anticipatory reaching motor behavior characterizes patients within the Alzheimer’s disease continuum in a virtual reality environment (opens in new window)

Author(s): Alessia de Nobile, Ilaria Borghi, Paolo De Pasquale, Denise Jennifer Berger, Antonella Maselli, Francesco Di Lorenzo, Elena Savastano, Martina Assogna, Andrea Casarotto, Daniele Bibbo, Silvia Conforto, Francesco Lacquaniti, Giacomo Koch, Andrea d’Avella, Marta Russo
Published in: Alzheimer's Research & Therapy, 2025, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.21203/rs.3.rs-5615872/v1

Understanding brain states across spacetime informed by whole-brain modelling (opens in new window)

Author(s): Jakub Vohryzek, Joana Cabral, Peter Vuust, Gustavo Deco, Morten L. Kringelbach
Published in: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Issue 380, 2022, ISSN 1364-503X
Publisher: Royal Society of London
DOI: 10.1098/rsta.2021.0247

The arrow of time of brain signals in cognition: Potential intriguing role of parts of the default mode network (opens in new window)

Author(s): Gustavo Deco, Yonatan Sanz Perl, Laura de la Fuente, Jacobo D. Sitt, B. T. Thomas Yeo, Enzo Tagliazucchi, Morten L. Kringelbach
Published in: Network Neuroscience, Issue 7, 2023, Page(s) 966-998, ISSN 2472-1751
Publisher: MIT Press
DOI: 10.1162/netn_a_00300

LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics (opens in new window)

Author(s): Giulio Ruffini,Giada Damiani, Diego Lozano-Soldevilla, Nikolas Deco, Fernando E. Rosas, Narsis A. Kiani, Adrián Ponce-Alvarez, Morten L. Kringelbach, Robin Carhart-Harris, Gustavo Deco
Published in: Plos Computational Biology, 2023, ISSN 1553-7358
Publisher: PLOS
DOI: 10.1371/journal.pcbi.1010811

Dynamic sensitivity analysis: Defining personalised strategies to drive brain state transitions via whole brain modelling (opens in new window)

Author(s): Jakub Vohryzek, Joana Cabral, Francesca Castaldo, Yonatan Sanz-Perl, Louis-David Lord, Henrique M. Fernandes, Vladimir Litvak, Morten L. Kringelbach, Gustavo Deco
Published in: Computational and Structural Biotechnology Journal, 2023, ISSN 2001-0370
Publisher: Elsevier
DOI: 10.1016/j.csbj.2022.11.060

Effects of classic psychedelic drugs on turbulent signatures in brain dynamics (opens in new window)

Author(s): Josephine Cruzat, Yonatan Sanz Perl, Anira Escrichs, Jakub Vohryzek, Christopher Timmermann, Leor Roseman, Andrea I. Luppi, Agustin Ibañez, David Nutt, Robin Carhart-Harris, Enzo Tagliazucchi, Gustavo Deco, Morten L. Kringelbach
Published in: Network Neuroscience, Issue 6, 2022, Page(s) 1104-1124, ISSN 2472-1751
Publisher: MIT Press
DOI: 10.1162/netn_a_00250

Functional harmonics reveal multi-dimensional basis functions underlying cortical organization (opens in new window)

Author(s): Katharina Glomb, Morten L. Kringelbach, Gustavo Deco, Patric Hagmann, Joel Pearson, Selen Atasoy
Published in: Cell Reports, Issue 36, 2022, Page(s) 109554, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109554

Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness (opens in new window)

Author(s): Milan Van Maldegem, Jakub Vohryzek, Selen Atasoy, Naji Alnagger, Paolo Cardone, Vincent Bonhomme, Audrey Vanhaudenhuyse, Athena Demertzi, Oceane Jaquet, Mohamed Ali Bahri, Pablo Nunez, Morten L. Kringelbach, Emmanuel A. Stamatakis, Andrea I. Luppi
Published in: British Journal of Anaesthesia, Issue 134, 2025, Page(s) 1088-1104, ISSN 0007-0912
Publisher: Oxford University Press
DOI: 10.1016/j.bja.2024.12.036

Multiscale effects of excitatory-inhibitory homeostasis in lesioned cortical networks: A computational study (opens in new window)

Author(s): Francisco Páscoa dos Santos, Jakub Vohryzek, Paul F. M. J. Verschure
Published in: PLOS Computational Biology, Issue 19, 2023, Page(s) e1011279, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pcbi.1011279

Addressing transcranial electrical stimulation variability through prospective individualized dosing of electric field strength in 300 participants across two samples: the 2-SPED approach (opens in new window)

Author(s): Sybren Van Hoornweder, Kevin A Caulfield, Michael Nitsche, Axel Thielscher, Raf L J Meesen
Published in: Journal of Neural Engineering, Issue 19, 2022, Page(s) 056045, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac9a78

A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings (opens in new window)

Author(s): Roser Sanchez-Todo, André M. Bastos, Edmundo Lopez-Sola, Borja Mercadal, Emiliano Santarnecchi, Earl K. Miller, Gustavo Deco, Giulio Ruffini
Published in: NeuroImage, Issue 270, 2023, Page(s) 119938, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.119938

Rare long-range cortical connections enhance human information processing (opens in new window)

Author(s): Gustavo Deco, Yonathan Sanz Perl, Peter Vuust, Enzo Tagliazucchi, Henry Kennedy, Morten L. Kringelbach
Published in: Current Biology, Issue 31, 2023, Page(s) 4436-4448.e5, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2021.07.064

A physical neural mass model framework for the analysis of oscillatory generators from laminar electrophysiological recordings (opens in new window)

Author(s): Roser Sanchez-Todo; André M. Bastos; Edmundo Lopez Sola; Borja Mercadal; Emiliano Santarnecchi; Earl K. Miller; Gustavo Deco; Giulio Ruffini
Published in: NeuroImage, 2023, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.119938

A ventromedial visual cortical ‘Where’ stream to the human hippocampus for spatial scenes revealed with magnetoencephalography (opens in new window)

Author(s): Edmund T. Rolls, Xiaoqian Yan, Gustavo Deco, Yi Zhang, Veikko Jousmaki, Jianfeng Feng
Published in: Communications Biology, Issue 7, 2024, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-06719-z

Transcranial magnetic stimulation of the brain: What is stimulated? – A consensus and critical position paper (opens in new window)

Author(s): Hartwig R. Siebner, Klaus Funke, Aman S. Aberra, Andrea Antal, Sven Bestmann, Robert Chen, Joseph Classen, Marco Davare, Vincenzo Di Lazzaro, Peter T. Fox, Mark Hallett, Anke N. Karabanov, Janine Kesselheim, Mikkel M. Beck, Giacomo Koch, David Liebetanz, Sabine Meunier, Carlo Miniussi, Walter Paulus, Angel V. Peterchev, Traian Popa, Michael C. Ridding, Axel Thielscher, Ulf Ziemann, John C. Rothwel
Published in: Clinical Neurophysiology, Issue 140, 2023, Page(s) 59-97, ISSN 1388-2457
Publisher: Elsevier BV
DOI: 10.1016/j.clinph.2022.04.022

Is artificial consciousness achievable? Lessons from the human brain (opens in new window)

Author(s): Michele Farisco, Kathinka Evers, Jean-Pierre Changeux
Published in: Neural Networks, Issue 180, 2024, Page(s) 106714, ISSN 0893-6080
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neunet.2024.106714

Dynamical consequences of regional heterogeneity in the brain’s transcriptional landscape (opens in new window)

Author(s): Gustavo Deco, Morten L. Kringelbach, Aurina Arnatkeviciute, Stuart Oldham, Kristina Sabaroedin, Nigel C. Rogasch, Kevin M. Aquino, Alex Fornito
Published in: Science Advances, Issue 7, 2024, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.abf4752

The human language effective connectome (opens in new window)

Author(s): Edmund T. Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Feng
Published in: NeuroImage, Issue 258, 2024, Page(s) 119352, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2022.119352

Modelling on the very large-scale connectome (opens in new window)

Author(s): Géza Ódor, Michael T Gastner, Jeffrey Kelling, Gustavo Deco
Published in: Journal of Physics: Complexity, Issue 2, 2021, Page(s) 045002, ISSN 2632-072X
Publisher: IOP Publishing
DOI: 10.1088/2632-072x/ac266c

From chimeras to extensive chaos in networks of heterogeneous Kuramoto oscillator populations (opens in new window)

Author(s): Pol Floriach, Jordi Garcia-Ojalvo, Pau Clusella
Published in: Chaos: An Interdisciplinary Journal of Nonlinear Science, Issue 35, 2025, ISSN 1054-1500
Publisher: American Institute of Physics
DOI: 10.1063/5.0243379

Complex spatiotemporal oscillations emerge from transverse instabilities in large-scale brain networks (opens in new window)

Author(s): Pau Clusella, Gustavo Deco, Morten L. Kringelbach, Giulio Ruffini, Jordi Garcia-Ojalvo
Published in: PLOS Computational Biology, Issue 19, 2023, Page(s) e1010781, ISSN 1553-7358
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pcbi.1010781

The Algorithmic Agent Perspective and Computational Neuropsychiatry: From Etiology to Advanced Therapy in Major Depressive Disorder (opens in new window)

Author(s): Giulio Ruffini, Francesca Castaldo, Edmundo Lopez-Sola, Roser Sanchez-Todo, Jakub Vohryzek
Published in: Entropy, Issue 26, 2024, Page(s) 953, ISSN 1099-4300
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/e26110953

The lack of temporal brain dynamics asymmetry as a signature of impaired consciousness states (opens in new window)

Author(s): Elvira G-Guzmán, Yonatan Sanz Perl, Jakub Vohryzek, Anira Escrichs, Dragana Manasova, Başak Türker, Enzo Tagliazucchi, Morten Kringelbach, Jacobo D. Sitt, Gustavo Deco
Published in: Interface Focus, Issue 13, 2023, ISSN 2042-8901
Publisher: The Royal Society
DOI: 10.1098/rsfs.2022.0086

Non-invasive brain stimulation and neuroenhancement (opens in new window)

Author(s): Andrea Antal, Bruce Luber, Anna-Katharine Brem, Marom Bikson, Andre R. Brunoni, Roi Cohen Kadosh, Veljko Dubljević, Shirley Fecteau, Florinda Ferreri, Agnes Flöel, Mark Hallett, Roy H. Hamilton, Christoph S. Herrmann, Michal Lavidor, Collen Loo, Caroline Lustenberger, Sergio Machado, Carlo Miniussi, Vera Moliadze, Michael A Nitsche, Simone Rossi, Paolo M. Rossini, Emiliano Santarnecchi, Margitta
Published in: Clinical Neurophysiology Practice, Issue 7, 2024, Page(s) 146-165, ISSN 2467-981X
Publisher: Elsevier BV
DOI: 10.1016/j.cnp.2022.05.002

Modulation of Cortical Excitability and Oscillatory Dynamics by transcranial Electrical Stimulation

Author(s): Guillermo Sánchez-Garrido Campos
Published in: 2025
Publisher: Universidad Pablo de Olavide

Validation and Refinement of a Laminar Neural Mass Model Using in vivo Mice Data

Author(s): Martina Moreno Fina, Pau Clusella Coberó, Roser Sánchez-Todo, and Jordi Soriano Fradera
Published in: Universitat de Barcelona, 2023
Publisher: Universitat de Barcelona

Impact of transcranial Electrical Stimulation on the Cortical Excitation/Inhibition Balance

Author(s): Marta Estévez Rodríguez
Published in: 2025
Publisher: Universidad Pablo de Olavide

Digital Twins for Model-driven Non-invasive Brain Stimulation in Alzheimer's Disease

Author(s): Roser Sanchez-Todo
Published in: 2025
Publisher: Universitat Pompeu Fabra

Brain dynamics of classical psychedelics show paradoxical hierarchical flattening with increased complexity (opens in new window)

Author(s): Jakub Vohryzek, Elvira Garcia Guzman, Morten L Kringelbach, Edmundo Lopez-Sola, Christopher Timmermann, Leor Roseman, Enzo Tagliazucchi, Giulio Ruffini, Robin Carhart-Harris, Gustavo Deco, Yonatan Sanz Perl
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.21.629922

Cross-Frequency Coupling as a Neural Substrate for Prediction Error Evaluation: A Laminar Neural Mass Modeling Approach (opens in new window)

Author(s): Giulio Ruffini, Edmundo Lopez-Sola, Raul Palma, Roser Sanchez-Todo, Jakub Vohryzek, Francesca Castaldo, Karl Friston
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.19.644090

Spherical harmonics representation of the steady-state membrane potential shift induced by tDCS in realistic neuron models (opens in new window)

Author(s): Adrià Galan-Gadea, Ricardo Salvador, Fabrice Bartolomei, Fabrice Wendling, Giulio Ruffini
Published in: 2022
Publisher: bioRxiv
DOI: 10.1101/2022.07.19.500653

Phase-synchronized 40Hz tACS and iTBS effects on gamma oscillations (opens in new window)

Author(s): Benedikt Glinski, Mohammed Ali Salehinejad, Kuri Takahashi, Asif Jamil, Fatemeh Yavari, Min-Fang Kuo, Michael A. Nitsche
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.14.643227

Bridging local and global dynamics: a biologically grounded model for cooperative and competitive interactions in the brain (opens in new window)

Author(s): Borja Mercadal, Maria Guasch-Morgades, Lucia Mencarelli, Giacomo Koch, Giulio Ruffini, null null
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.07.09.663817

A Randomized Sham-Control Trial for Home-Based Transcranial Alternating Current Stimulation (tACS) In Alzheimer’s Disease (opens in new window)

Author(s): Lucia Mencarelli, Martina Assogna, Elena Savastano, Ilaria Borghi, Francesca Candeo, Sonia Bonnì, Francesco Di Lorenzo, Roser Sanchez-Todo, Ricardo Salvador, Emiliano Santarnecchi, Giulio Ruffini, Giacomo Koch
Published in: medRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.04.14.25325464

Analysis and extension of exact mean-field theory with dynamic synaptic currents (opens in new window)

Author(s): Giulio Ruffini
Published in: 2022
Publisher: bioRxiv
DOI: 10.1101/2021.09.01.458563

Regular and sparse neuronal synchronization are described by identical mean field dynamics (opens in new window)

Author(s): Clusella, Pau; Montbrió, Ernest
Published in: 2022
Publisher: arxiv
DOI: 10.48550/arxiv.2208.05515

Group optimization methods for dose planning in tES (opens in new window)

Author(s): R. Salvador, J. Zhou, B. Manor, G. Ruffini
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.18.643934

The 2D Ising model, criticality and AIT (opens in new window)

Author(s): Giulio Ruffini and Gustavo Deco
Published in: 2021
Publisher: bioRxiv
DOI: 10.1101/2021.10.21.465265

An engine for systematic discovery of cause-effect relationships between brain structure and function (opens in new window)

Author(s): Andrea I. Luppi, Filip Milisav, Laura E. Suarez, Golia Shafiei, Jakub Vohryzek, Yonatan Sanz Perl, Hana Ali, Fernando E. Rosas, Pedro A. M. Mediano, Bratislav Misic, Gustavo Deco, Morten Kringelbach
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.04.05.647237

Fast Interneuron Dysfunction in Laminar Neural Mass Model Reproduces Alzheimer’s Oscillatory Biomarkers (opens in new window)

Author(s): Roser Sanchez-Todo, Borja Mercadal, Edmundo Lopez-Sola, Maria Guasch-Morgades, Gustavo Deco, Giulio Ruffini
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.26.645407

Kuramoto model for populations of quadratic integrate-and-fire neurons with chemical and electrical coupling (opens in new window)

Author(s): Pau Clusella; Bastian Pietras; Ernest Montbrió
Published in: 2021
Publisher: arxiv
DOI: 10.48550/arxiv.2110.07665

Design of effective personalised perturbation strategies for enhancing cognitive intervention in Alzheimer’s disease (opens in new window)

Author(s): Jakub Vohryzek, Joana Cabral, Yonatan Sanz Perl, Murat Demirtas, Carles Falcon, Juan Domingo Gispert, Beatriz Bosch, Mircea Balasa, Morten Kringelbach, Raquel Sanchez-Valle, Giulio Ruffini, Gustavo Deco
Published in: 2023
Publisher: bioRxiv
DOI: 10.1101/2023.04.20.537688

Dynamical repertoire of brain networks in mindfulness cognitive behavioural therapy during rumination: A randomized controlled trial (opens in new window)

Author(s): Jakub Vohryzek, Anne Maj van der Velden, Willem Kuyken, Jesus Montero-Marin, Guusje Collin, Morten L Kringelbach, Eric Ruhe
Published in: medRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.02.04.25321569

Restoring Oscillatory Dynamics in Alzheimer’s Disease: A Laminar Whole-Brain Model of Serotonergic Psychedelic Effects (opens in new window)

Author(s): Jan C. Gendra, Edmundo Lopez-Sola, Francesca Castaldo, Èlia Lleal-Custey, Roser Sanchez-Todo, Jakub Vohryzek, Ricardo Salvador, Ralph G. Andrzejak, Giulio Ruffini, null null
Published in: bioRxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.15.628565

Deep learning the arrow of time in brain activity: characterising brain-environment behavioural interactions in health and disease (opens in new window)

Author(s): Gustavo Deco, Yonatan Sanz Perl, Jacobo D. Sitt, Enzo Tagliazucchi, Morten L. Kringelbach
Published in: 2021
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.07.02.450899

Competitive interactions shape brain dynamics and computation across species (opens in new window)

Author(s): Andrea I Luppi, Yonatan Sanz Perl, Jakub Vohryzek, Pedro A.M. Mediano, Fernando E Rosas, Filip Milisav, Laura Estefany Suarez, Silvia Gini, Daniel Gutierrez-Barragan, Alessandro Gozzi, Bratislav Misic, Gustavo Deco, Morten L Kringelbach
Published in: bioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.19.619194

TH-230. Mechanistic understanding of Alzheimer’s disease through hybrid brain models: from mesoscale to macroscale, and design of personalized stimulation protocols (opens in new window)

Author(s): R Sanchez-Todo, EL Sola, R Salvador, MC Biagi, G Deco, G Ruffini
Published in: 2022
Publisher: Clinical Neurophysiology
DOI: 10.1016/j.clinph.2022.07.416

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