The Energetics and Habitat of Metabolic Origin

Project Information

EcolMetabOrigin

Grant agreement ID: 101018894

DOI 10.3030/101018894

EC signature date 1 May 2021

Start date 1 November 2021

End date 31 October 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 490 000,00

EU contribution € 2 490 000,00

Coordinated by

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

Publications

Peer reviewed articles (14)

Serpentinization as the source of energy, electrons, organics, catalysts, nutrients and pH gradients for the origin of LUCA and life

Author(s): Schwander L, Brabender M, Mrnjavac N, Wimmer JLE, Preiner M, Martin WF
Published in: Frontiers in Microbiology, Issue 14, 2023, Page(s) 1257597, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2023.1257597

Gene Duplications Are At Least 50 Times Less Frequent than Gene Transfers in Prokaryotic Genomes

Author(s): Fernando D K Tria, William F Martin
Published in: Genome Biology and Evolution, Issue 13/10, 2021, ISSN 1759-6653
Publisher: Oxford University Press
DOI: 10.1093/gbe/evab224

Ambient temperature CO2 fixation to pyruvate and subsequently to citramalate over iron and nickel nanoparticles

Author(s): Beyazay T, Belthle KS, Farès C, Preiner M, Moran J, Martin WF, Tüysüz H
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-36088-w

Narrowing gaps between Earth and life

Author(s): Martin WF
Published in: Proc Natl Acad Sci USA, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2216017119

Pyrophosphate and Irreversibility in Evolution, or why PPi Is Not an Energy Currency and why Nature Chose Triphosphates

Author(s): Jessica L. E. Wimmer, Karl Kleinermanns, William F. Martin
Published in: Frontiers in Microbiology, Issue 12, 2021, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2021.759359

The ancestral mitotic state: Closed orthomitosis with intranuclear spindles in the syncytial last eukaryotic common ancestor.

Author(s): Bremer N, Tria FDK, Skejo J, Martin WF
Published in: Genome Biology and Evolution, 2023, ISSN 1759-6653
Publisher: Oxford University Press
DOI: 10.1093/gbe/evad016

A prebiotic Krebs cycle analog generates amino acids with H2 and NH3 over nickel

Author(s): Kaur H, Rauscher SA, Werner E, Song Y, Yi J, Kazöne W, Martin WF, Tüysüz H, Moran J
Published in: Chem, Issue 10, 2024, Page(s) 1-13, ISSN 2451-9294
Publisher: Cell Press
DOI: 10.1016/j.chempr.2024.02.001

Direct synthesis of formamide from CO2 and H2O with nickel–iron nitride heterostructures under mild hydrothermal conditions

Author(s): Beyazay T, Martin WF, Tüysüz H
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 19768–19779, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c05412

Ancestral state reconstructions trace mitochondria but not phagocytosis to the last eukaryotic common ancestor

Author(s): Bremer N, Tria FDK, Skejo J, Garg SG, Martin WF
Published in: Genome Biology and Evolution, 2022, ISSN 1759-6653
Publisher: Oxford University Press
DOI: 10.1093/gbe/evac079

Ferredoxin reduction by hydrogen with iron functions as an evolutionary precursor of flavin-based electron bifurcation

Author(s): Brabender M, Henriques Pereira DP, Mrnjavac N, Schlikker ML, Kimura Z-I, Sucharitakul J, Kleinermanns K, Tüysüz H, Buckel W, Preiner M, Martin WF
Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 121, 2024, Page(s) e2318969121, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2318969121

Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry

Author(s): Bishwa P. Subedi, William F. Martin, Vincenzo Carbone, Eduardus C. Duin, Bryan Cronin, Julia Sauter, Linley R. Schofield, Andrew J. Sutherland-Smith, Ron S. Ronimus
Published in: FEMS Microbes, 2021, ISSN 2633-6685
Publisher: Oxford University Press
DOI: 10.1093/femsmc/xtab012

Role of geochemical protoenzymes (geozymes) in primordial metabolism: specific abiotic hydride transfer by metals to the biological redox cofactor NAD+

Author(s): Delfina P. Henriques Pereira, Jana Leethaus, Tugce Beyazay, Andrey do Nascimento Vieira, Karl Kleinermanns, Harun Tüysüz, William F. Martin, Martina Preiner
Published in: The FEBS Journal, 2022, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.16329

Realistic Gene Transfer to Gene Duplication Ratios Identify Different Roots in the Bacterial Phylogeny Using a Tree Reconciliation Method.

Author(s): Nico Bremer; Michael Knopp; William F. Martin; Fernando D. K. Tria
Published in: Life; Volume 12; Issue 7; Pages: 995, Issue 1, 2022, ISSN 2075-1729
Publisher: MDPI AG
DOI: 10.3390/life12070995

Energy at Origins: Favorable Thermodynamics of Biosynthetic Reactions in the Last Universal Common Ancestor (LUCA)

Author(s): Jessica L. E. Wimmer; Joana C. Xavier; Andrey d. N. Vieira; Delfina P. H. Pereira; Jacqueline Leidner; Filipa L. Sousa; Karl Kleinermanns; Martina Preiner; William F. Martin
Published in: Frontiers in Microbiology, Issue 1, 2021, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2021.793664