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"Targeting the ""untargetable"" by merging biological and chemical compound libraries"

Publications

Solid-phase peptide synthesis in 384-well plates

Author(s): Mischa Schüttel, Edward Will, Gontran Sangouard, Anne Zarda, Sevan Habeshian, Alexander L. Nielsen, Christian Heinis
Published in: Journal of Peptide Science, 2024, ISSN 1075-2617
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/psc.3555

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Author(s): Zsolt Bognar; Ganesh K. Mothukuri; Alexander L. Nielsen; Manuel L. Merz; Peter M. F. Pânzar; Christian Heinis
Published in: Organic & Biomolecular Chemistry, Issue Volume 20, issue 29, 2022, Page(s) 5699-5703, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2ob00910b

De novo development of small cyclicpeptides that are orally bioavailable

Author(s): Manuel L. Merz, Sevan Habeshian, Bo Li, Jean-Alexandre G. L. David, Alexander L. Nielsen, Xinjian Ji, Khaled Il Khwildy, Maury M. Duany Benitez, Phoukham Phothirath, Christian Heinis
Published in: Nature Chemical Biology, 2023, ISSN 0000-0000
Publisher: Nature
DOI: 10.1038/s41589-023-01496-y

Cyclic Peptides for Drug Development

Author(s): Xinjian Ji; Alexander L. Nielsen; Christian Heinis
Published in: Angewandte Chemie International, Issue 1, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202308251

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