Death Receptors as Integrators of Stress-induced inflammation

Informations projet

DESTRESS

N° de convention de subvention: 101020534

DOI 10.3030/101020534

Date de signature de la CE 13 Août 2021

Date de début 1 Octobre 2021

Date de fin 30 Septembre 2026

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total € 2 499 386,25

Contribution de l’UE € 2 499 386,25

Coordonné par

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Publications

Peer reviewed articles (5)

Discriminating Between Apoptosis, Necrosis, Necroptosis, and Ferroptosis by Microscopy and Flow Cytometry

Auteurs: Aoife Costigan; Emilie Hollville; Seamus J. Martin
Publié dans: Current Protocols in Immunology, Numéro 2, 2023, Page(s) 1-31, ISSN 2691-1299
Éditeur: WILEY
DOI: 10.1002/cpz1.951

Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement

Auteurs: Graeme P Sullivan 1, Pavel Davidovich , Natalia Muñoz-Wolf 2 3 , Ross W Ward 2 , Yasmina E Hernandez Santana 4 , Danielle M Clancy 1 , Aoife Gorman 2 , Zaneta Najda 1 , Boris Turk 5 , Patrick T Walsh 4 5 , Ed C Lavelle 2 , Seamus J Martin 1
Publié dans: Science Immunology, Numéro 7, 2022, Page(s) 1-15, ISSN 2470-9468
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.ade5728

cFLIPL acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes

Auteurs: Davidovich, P., Higgins, C.A., Najda, Z., Longley, D.B. and Martin S.J.
Publié dans: Cell Reports, Numéro 42, 2023, Page(s) 1-17, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2023.113476

IL-1 family cytokines serve as 'activity recognition receptors' for aberrant protease activity indicative of danger

Auteurs: Seamus J, Martin; Valentina, Frezza; Pavel, Davidovich; Zaneta, Najda; Danielle M, Clancy
Publié dans: Cytokine, Numéro 157, 155935, 2022, Page(s) 1-10, ISSN 1043-4666
Éditeur: Academic Press
DOI: 10.1016/j.cyto.2022.155935

Unleashing dendritic cell-mediated tumor clearance by targeting Bcl-2

Auteurs: Seamus J. Martin
Publié dans: Trends in Immunology, Numéro 11, 2023, Page(s) 871-873, ISSN 1471-4906
Éditeur: Elsevier BV
DOI: 10.1016/j.it.2023.09.007