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Unlocking vital mysteries in respiratory biomechanics

Project description

Innovative model to study lung respiratory dynamics

The EU-funded BREATHE project aims to develop the first comprehensive computational model of the respiratory system, based on recent advances in high-performance simulation. The strategy will build on a recent model of an exascale-ready incompressible flow solver which will be modified for lung-specific challenges and will include capabilities to capture tissue interaction and gas transport. The respiratory zone will be represented by multiphase poroelastic media with specific pleural boundaries, and coupled pulmonary circulation will be represented by an embedded reduced dimensional network and additional phases. Individualisation of the model and adaptation to the conditions of disease progression will be achieved using a novel probabilistic learning approach. The developed model system will provide insights into the dynamic processes in human lungs for biomedical scientists and practitioners.

Host institution

TECHNISCHE UNIVERSITAET MUENCHEN
Net EU contribution
€ 2 499 160,00
Address
Arcisstrasse 21
80333 Muenchen
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Beneficiaries (1)

TECHNISCHE UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 2 499 160,00
Address
Arcisstrasse 21
80333 Muenchen

See on map

Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00