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Exosome inspired RNA communication between HiErarchicaL poLymer prOtocells

Project description

Artificial exosomes unveil important aspects of RNA communication

Engineering living systems that mimic key biological processes is a major challenge. At the same time, synthetic systems offer a powerful tool for studying cellular communication pathways and understanding cellular processes. The EU-funded RNAhello project seems to have found a way to study RNA-based communication in artificial protocells. The proposed approach is inspired by exosomes, cell-secreted vesicles that carry various macromolecules and facilitate intercellular communication. RNAhello will construct such vesicles from polymers and employ them as mRNA shuttles between distinct protocell populations. Results will provide fundamental knowledge about nucleic acid transfer and establish a powerful tool for drug discovery.

Coordinator

TECHNISCHE UNIVERSITEIT EINDHOVEN
Net EU contribution
€ 175 572,48
Address
Groene Loper 3
5612 AE Eindhoven
Netherlands

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Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Higher or Secondary Education Establishments
Other funding
€ 175 572,48