Description du projet
Aspects sociaux liés à l’introduction de nouvelles technologies de santé: le paradigme des vaccins COVID-19
La pandémie de COVID-19 a contraint les autorités réglementaires à prendre des mesures d’urgence et à ouvrir la voie à de nouvelles technologies de développement de vaccins. Bien que l’ARNm soit susceptible de révolutionner les domaines de la conception de vaccins et de médicaments, son acceptation sociale est un aspect à ne pas négliger. L’objectif du projet GENEVACRISIS, financé par l’UE, est de comprendre le rôle de la perception sociale dans l’introduction de nouvelles technologies. Les chercheurs collecteront des propos recueillis lors d’entrevues et de discussions de groupe avec des scientifiques, des décideurs politiques et des spécialistes de la communication scientifique, et étudieront de quelle manière ils ont pu affecter la réaction des gens à la technologie. Le projet aidera à aborder des situations similaires à l’avenir.
Objectif
The coronavirus pandemic has disrupted our ways of living across the globe. This research project will use social science and humanities approaches to analyse the enabling role of the coronavirus crisis in the development and (potential) deployment of emerging genetic vaccine technology, and associated transformations in social values and scientific research practices. Although traditional routes are being utilised to develop vaccine candidates, the pandemic has thrown open doors for the introduction of the state of the art genetic vaccines as an emergency response, e.g. Moderna Inc.’s vaccine candidate ‘mRNA-1273’. The underlying mRNA technology presents a completely new yet unproven therapeutic modality, which scientists believe has the potential to disrupt the drug development domain. In practice, only a few gene therapy approaches have received drug approval, and these are mainly aimed at treating rare hereditary conditions. In contrast, genetic vaccines would potentially be administered to the general population, both healthy and affected. They would hence normalise the mRNA medicine platforms. However, the state of the art mRNA therapeutics in general and genetic vaccine technology in particular is yet to undergo serious scrutiny and analysis from a social science perspective, a gap and original research problem that this project aims to address. The project will examine narratives around the Covid-19 pandemic, and through interviews and focus group discussions with scientists, policymakers, and science communicators will explore its enabling role in the introduction of genetic vaccine technology. Furthermore, it will analyse the ways in which these developments might shift social values and research practices. The research outcomes will provide key insights to policymakers for the governance of DNA and mRNA therapeutics platforms, and enhance social science understanding of how narratives of crisis co-shape our response to emerging science and technology.
Champ scientifique
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health sciencesmedical biotechnologygenetic engineeringgene therapy
- medical and health scienceshealth sciencespublic healthepidemiologypandemics
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
Mots‑clés
Programme(s)
Régime de financement
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)Coordinateur
EH8 9YL Edinburgh
Royaume-Uni