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The role of temperature and transmission route on parasite epidemiological, ecological and evolutionary dynamics

Project description

The role of the environment in host-parasite dynamics

Influenza outbreaks occur each winter, indicating that seasonality is a common characteristic of epidemic infections. However, little is known about the influence of different environmental factors such as temperature or other species in the community on host-parasite interactions. The EU-funded EpiEcoEvo project will employ the small crustacean Daphnia magna and its bacterial parasite Pasteuria ramosa as a model system for studying host-parasite relationships within the broader ecosystem. Researchers will combine experimentation and field observations with mathematical modelling to unveil the role of the biotic and abiotic environment in host-parasite dynamics. Results will provide important information on the ecological drivers of infectious diseases.

Objective

Despite their clear importance and potential to broadly influence host populations, little is known about pathogen interactions within a broader ecosystem. This project will use the well-studied Daphnia magna-Pasteuria ramosa host-parasite system as a model to investigate how various factors (temperature, route of transmission and selection for host resistance) interact to influence the repeatable seasonal epidemic dynamics observed in nature in order to further understand the ecological and evolutionary drivers of epidemics. The novelty offered by this project is that it will be using a combination of field observations, mesocosm and laboratory experiments along with mathematical modelling, aiming to quantify and measure the relative importance of factors that are often recognised to be important for epidemic dynamics, but not well understood. The originality offered by this project is that it will allow us to disentangle the complex relationships between hosts, parasites, the broader ecological community, and the abiotic environment and gain further insight to the rules that govern epidemic cycles and ecological feedback loops. By doing so, it allows to estimate the effect of climate change (in particular warmer summers) on the future dynamics of this host-parasite system. Understanding the drivers of infectious disease dynamics and the complex mechanisms of transmission and their relationship to the biotic and abiotic environment are more important than ever as we face the dual and linked challenges of global change and emerging infectious diseases.

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MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

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(opens in new window) H2020-MSCA-IF-2020

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Coordinator

UNIVERSITAT BASEL
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 191 149,44
Address
PETERSPLATZ 1
4051 Basel
Switzerland

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Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 191 149,44
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