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Nanolasers for in-vivo deep in tissue neuron activation and action potential sensing

Project description

Nanolasers offer great promise for deep imaging of living tissues

Interfacing biology at the nanometer scale with lasers will open new avenues for the integration of small sensors and actuators into biological tissue. Scientists are striving to create increasingly smaller laser systems that can concentrate high optical powers in small volumes and consume less energy. This is expected to lead to important insights about the brain and how to interface it, giving rise to more powerful emergent technologies for the next generation of Brain-Computer interfaces. Funded by the Marie Skłodowska-Curie Actions programme, the Neuralase project aims to extend nanolaser use to in vivo studies to bridge different scientific disciplines exploring the physics and engineering of biological sensing.

Objective

Summary
Nanolasers offer the ultimate photonic gadget with unique properties as biosensors and actuators. Lasers at the nanoscale can concentrate high optical powers in small volumes and use a fraction of the power required to drive a conventional laser. Recently, nanolasers and nanoresonators have seen use for biosensing, with the focus so far on in-vitro biochemistry. Translating this approach to in-vivo is complex but promises to link relevant in-vivo physiological information with chemical pathways. This project aims to integrate photonic architectures for in-vivo deep-tissue exploration and to translate this technology to areas where probing the local environment with light has an immediate impact, such as the Brain. My proposed research thus bridges different scientific disciplines exploring the physics of biological sensing.
I foresee 3 major efforts to succeed in this research:
1 – Design of micro- and nanocavities operating in the IR.
2 – In vitro characterization through highly scattering media.
3 – In vivo investigations for deep-tissue sensing.

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Topic(s)

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MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

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(opens in new window) H2020-MSCA-IF-2020

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Coordinator

UNIVERSITAT ZU KOLN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 174 806,40
Address
ALBERTUS MAGNUS PLATZ
50931 KOLN
Germany

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Region
Nordrhein-Westfalen Köln Köln, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 174 806,40
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