Scholars recently observe an increasing spatial disconnect between research and development (R&D) activities within global firms, in particular from emerging markets. These firms off-shore their research activities to centers of state-of-the-art knowledge while they might keep product development closer to their original locations. This is of major concern to our society because this spatial split channels global knowledge flows and affects the ability of regions to produce innovative output. This project aims at understanding the dynamics of spatial (re-)organization of R&D in relation to firm development. Because we still know too little about how stable this spatial disconnect is, based on initial evidence that it might only temporary exists, DISCO uses information from patents to build an indicator and a firm-typology revealing the global patterns of which type of R&D activity is performed at which locations and how this changes over time. The project provides a quantitative measure for the type of R&D activity that goes beyond the qualitative measures often used to study this phenomenon. Applying the indicator reveals for instance similarities and differences between the R&D internationalization of emerging and established market firms. This can yield new evidence on innovation capability building and successful development trajectories in R&D internationalization. The findings provide a more profound understanding of the temporality of globally splitting R&D activities, with implications for firms and the regional development of emerging as well as established markets.