Project description
New approach to synthesising saturated organic molecules
Carbon–carbon bond formation is a fundamental transformation of synthetic organic chemistry. Understanding the nature of these transformation processes is essential to improving our knowledge of chemical phenomena. Funded by the Marie Skłodowska-Curie Actions programme, the overall aim of the CatToSat project is to devise new organic chemical methods to access general, modular C(sp3)–C(sp3) bond-forming reactions that should result in highly saturated organic molecules. Transition metal catalysts and abundant reagents, such as ubiquitous alkyl carboxylic acids and feedstock olefins, will be used in the reactions. The resulting highly saturated compounds may prove to be of great significance to the pharmaceutical industry.
Objective
The construction of C-C bonds represents the foundation of synthetic organic chemistry. Specifically, the installation of (sp3)-hybridized carbons is among the most important transformations in an organic chemist’s toolbox due to the prevalence of alkyl-alkyl bonds in organic molecules. Furthermore, compounds featuring a high degree of saturation grant access to greater chemical space and are more likely to yield clinical success in drug discovery and development. The overall aim of the proposed research is to devise new technologies in organic chemistry to access general, modular and applicable C(sp3)-C(sp3) bond-forming reactions, providing high degrees of saturation in organic molecules. Transition metal catalysis will be the foundation for this proposal, in which the most accessible sources for reagents will be used, such as ubiquitous alkyl carboxylic acids and feedstock olefins. In order to accomplish the overarching goal of this research program, the outgoing phase of this fellowship will take place during the first two years in the laboratory of Prof. Phil Baran at Scripps Research, La Jolla, USA. The incoming phase will take place during the final third year in the laboratory of Prof. Bill Morandi at ETH Zürich, Switzerland.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
8092 Zuerich
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.