Project description
Predicting the impacts of climate change on plant-pathogen interactions
Numerous studies of molecular plant-pathogen interactions have probed the precise combinations of host and pathogen genes that lead to susceptibility or resistance. Although valuable, laboratory trials cannot directly predict when and where a disease will develop (pathogenesis) in natural or agricultural plant populations, as environmental factors also play a role. The EU-funded PathoGenoPredict project will create a framework that enables scientists to predict plant pathogenesis and account for spatiotemporal variation in both host and pathogen genetics over the landscape and through time. The research fellow will investigate the genetic interaction of Hyaloperonospora arabidopsidis, a model fungus-like organism known as an oomycete, and the model plant Arabidopsis thaliana across the landscape, producing maps both for today's climate and predicted future climate change.
Objective
Plants and their pathogens are locked in an ongoing coevolutionary battle, with outcomes affecting food and environmental security. Pathogenesis can occur when a host's resistance and pathogen's virulence genotypes are compatible with infection, while incompatible genotypes lead to resistance. A myriad of studies of molecular plant-pathogen interactions have probed the precise combinations of host (R) and pathogen (Avr) genes that lead to susceptibility or resistance. While laboratory trials are valuable, they cannot directly predict when and where pathogenesis will occur in natural or agricultural plant populations, as environmental factors also play a role. In this fellowship, I will build predictions of plant pathogenesis that account for spatiotemporal variation in both host and pathogen genetics over the landscape and through time.
I will investigate the model system of Hyaloperonospora arabidopsidis (Hpa; an oomycete) and Arabidopsis thaliana (Ath; a plant). Existing work in this system has identified the molecular mechanisms underlying multiple disease resistance phenotypes. I propose to extend this work by evaluating the genetic interaction of Hpa and Ath across the landscape. Specifically, I aim to
1) Determine the spatial distribution of genetic diversity across the landscape in both Ath and Hpa, investigating both neutral genome-wide patterns and R/Avr gene loci.
2) Model genetic variation in R/Avr genes across the landscape, producing maps both for today’s climate, and under predicted future climate change.
3) Predict how genetics interacts with a variable environment, including a changing climate, to produce disease, including future changes in the coevolutionary balance between plant and pathogen due to climate-induced range shifts.
These aims facilitate the projection of molecular plant-pathogen interactions onto the landscape, and provide a framework to examine the molecular mechanisms underlying ecological interaction of plants and their pathogens.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80539 MUNCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.