The role of bacteriocins in biofilm formation
Bacteriocins are a group of antimicrobial peptides produced by bacteria as a protection strategy against other bacteria. They are found in gene clusters that encompass genes involved in bacteriocin production, immunity and transport. The scope of the EU-funded BOB project is to map bacteriocin gene clusters with associated immunity proteins in oral streptococci. By combining experimental methods and bioinformatics, researchers will explore the role of bacteriocin immunity genes in bacteria interacting during biofilm formation. Moreover, considering that bacteriocins have been suggested as potential alternatives to antibiotics in the future, project results will have important consequences for the healthcare sector.