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Targeting human kallikreins involved in ovarian cancer pathogenesis: novel activity based probes and kallikrein-based therapeutic strategies.

Project description

Novel biomarkers for ovarian cancer diagnosis

Most patients with ovarian cancer present with metastases at the time of diagnosis, necessitating the identification of novel biomarkers for prompt diagnosis. The EU-funded KLKs4OvCa project will focus on kallikrein-related peptidases (KLKs), a family of enzymes that participate in a broad spectrum of biological processes. Since KLKs are upregulated in ovarian cancer and associated with dismal prognosis, scientists aim to unveil their role in the disease by investigating their activity. Project results will determine the prognostic and therapeutic value of these biomarkers and help address the challenge of prompt ovarian cancer diagnosis.

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Coordinator

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Net EU contribution
€ 212 933,76
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
United Kingdom
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00