Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS

Applying novel analytical methods to elucidate bio-nano interactions at individual cell level in plants

Project description

Studying the effect of nanotechnology on plant cells

The use of engineered nanomaterials (ENMs) in agriculture, known as phytonanotechnology, helps in the controlled release of agrochemicals and the target-specific delivery of biomolecules to boost disease resistance, nutrient utilisation and crop yield. The EU-funded PhytoENM project will examine potential key cellular processes involved in the delivery of ENMs to plants and determine the safe use and social acceptance of phytonanotechnology. This will involve assessing potential adverse effects, including the risks associated with the transfer of ENMs through the food chain. To that end, PhytoENM will develop novel isotope labelling techniques to study metal-based ENMs and their distribution within individual cells, leading to information on their potential toxicity.

Objective

Phytonanotechnology (use of Engineered Nanomaterial, ENMs, in agriculture) supports the controlled release of agrochemicals (e.g. fertilizers, pesticides) and target-specific delivery of biomolecules (e.g. nucleotides, proteins, and activators) for increased disease resistance, nutrient utilization, and crop yield. Along with the groundbreaking potential of such techniques, one should be careful about their trophic transfer to plants. This topic has been rarely studied, compared to the toxic effect of ENMs in human systems. However, assessment of ENM toxicity to plant cells is critical to the implementation of nanotechnology in agriculture and support of global sustainability and the EC's European Green Deal. The proposed project addresses potential key cellular processes involved in the delivery of ENMs to plants and the safe use and social acceptance of phytonanotechnology, assessing potential adverse effects, including the risks associated with the transfer of ENMs through the food chain. To do so, novel analytical techniques are essential that could study metal-based ENMs and their distribution within individual cells. The development of Single Particle ICP-MS (SP-ICP-MS) is a new area of research which allows rapid detection and analysis of ENMs in a variety of matrices and applications, as it allows discrete pulses of positively charged ions to be detected and measured in a time resolved manner using microsecond data acquisition rates. PhytoENM will go beyond, applying the concept of Single Cell ICP-MS (SC-ICP-MS), where individual cells are rapidly analyzed for their particulate & ionic content, something that has not been done before in plants. The project will also use novel stable-isotope labelling techniques pioneered by the applicant team. This would allow the understanding of the interaction of metal-based ENMs in single cells spatially, and the related mechanistic pathways, leading to information on their distribution and potential toxicity.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

You need to log in or register to use this function

Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

See all projects funded under this funding scheme

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2020

See all projects funded under this call

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 224 933,76
Address
Edgbaston
B15 2TT Birmingham
United Kingdom

See on map

Region
West Midlands (England) West Midlands Birmingham
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 224 933,76
My booklet 0 0