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Nanomechanical spectrometry as an early alert system of the presence of airborne pathogens in critical settings

Project description

Detection device for airborne pathogens in hospitals

Hospitals pose a great risk for contracting infections often caused by more virulent or drug-resistant microorganisms. Preventing the spread requires an in-depth understanding of the transmission route of the pathogens. The EU-funded VirAIR project aims to bring to the clinic the first optomechanical device for the detection and identification of viruses in air and liquid samples. Airborne organisms are particularly dangerous as they can be directly inhaled or indirectly transmitted to patients through surfaces. Preliminary results are very promising, and in light of the SARS-CoV-2 pandemic, the VirAIR device may serve as an alert system for preventative medicine in hospital units.

Objective

Hospital acquired infections have been recognised as a healthcare associated risk for patients for at least a hundred years. The hospital environment may be contaminated with various environmental pathogens and with more virulent organisms. Airborne organisms can be inhaled, fall directly onto wounds or instruments or survive on surfaces and then be indirectly transmitted to patients. During the recent pandemic related to SARS-COV-2 and the Covid-19 disease, we have been aware that understanding the transmission routes is critical to stop the virus spread. In the framework of FET-PROACT-VIRUSCAN-731868 an optonanomechanical system for spectrometry of viruses from liquid samples is under development, bringing optomechanical devices to a diagnostic clinical application for the first time. IMN-CSIC has already registered two patents related to its work in the framework of VIRUSCAN, demonstrating the capability to identify unique intrinsic mechanical modes of pathogens and setting the adequate method to extract several parameters from the devices for their unequivocal identification. With the aim to contribute to minimize as much as possible the impact the current COVID-19 pandemic is having around the world, we decided to test the technology with inorganic nanoparticles present in the air environment. Results demonstrate that our mechano-optic system and method of analysis, also work for the identification and detection of viruses in air samples, being the aim of VirAIR to demonstrate and exploit its applicability for detecting SARS-COV-2 viral particles from the air environment as an early alert system of much interest for the preventive medicine units at hospitals. Such aim is out of the framework of VIRUSCAN, which is focused only on diagnostic applications and liquid samples. Thus, VirAIR main objective is to turn results from VIRUSCAN project into genuine societal and economic innovations, much needed now to contribute to stop the current COVID-19 pandemic spread.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

CSA - Coordination and support action

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Call for proposal

(opens in new window) H2020-FETOPEN-2018-2020

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Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Net EU contribution
€ 100 000,00
Address
CALLE SERRANO 117
28006 Madrid
Spain
Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Links
Total cost
No data