Using templates to direct enzymatic synthesis
In nature, biomolecular templates define the outcomes of enzymatic reactions in some of the most fundamental biological processes, such as DNA replication, transcription and translation. The EU-funded ENZYME-DCC project will investigate the possibility of using synthetic (artificial) templates to direct enzymatic reactions and access different products to those formed in nature. The researchers will explore a conceptually new approach to using enzymes for chemical synthesis that involves combining tools and concepts from synthetic chemistry with enzymology. In this new methodology, enzymes catalyse reversible reactions and generate complex dynamic mixtures of interconverting products. Artificial template molecules will then be added to recognise and select the desired products from the mixtures.
Fields of science
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Call for proposalSee other projects for this call
Funding SchemeERC - Support for frontier research (ERC)
2800 Kongens Lyngby
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