Objective
MiCRoARTiS is the blueprint for a five-year program of frontier research to develop a sophisticated spectroscopic approach to study artificial molecular motors. The ultimate goal will be to demonstrate the harnessing of conformational dynamics of molecular motors in the gas phase using microwave spectroscopy. My recent research has shown we can measure broadband microwave spectra of molecular motors in idle mode. Such achievement was remarkable not only because rotationally resolved studies of molecules of this size were out of reach until now, but also because it opens a gateway to a new research line that is risky and ambitious, but its potential is clear. Emerging from a static frame to studies of molecular motors in action in the gas phase will unlock their structural dynamics with unprecedented control over the environment. Molecular nanotechnology will gain a new experimental tool that is highly compatible with theoretical modelling approaches. The significance of this project emerges from the current lack of high-resolution probes that are able to capture a complete structural picture of the mechanical steps of these architectures. An evolved structure-solving tool will be developed, exploiting the unrivalled abilities of microwave spectroscopy to recover three-dimensional structures from rotationally resolved spectra. The virtual isolation created in gas phase molecular ensembles will be exploited to disclose intrinsic and interfacial structural manoeuvres of molecular motors. For the first time, rotationally resolved studies of molecular motors will be carried out in geared-mode, and in the gas phase. A new technology for thermal and optical control of samples will be developed to augment the molecular library at reach, carving a path for this methodology to extend beyond the five-year lifetime of the project. A new vision for spectroscopy of artificial molecular machinery will emerge and significantly advance this frontier of research.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2021-STG
See all projects funded under this callHost institution
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3004-531 COIMBRA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.