Deciphering cellular and viral determinants of lytic HSV-1 infection, latency and reactivation

Project Information

DecipherHSV

Grant agreement ID: 101041177

DOI

10.3030/101041177

EC signature date 27 April 2022

Start date 1 May 2022

End date 30 April 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 998 008,75

EU contribution

€ 1 998 008,75

Coordinated by

MEDIZINISCHE HOCHSCHULE HANNOVER
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Herpes simplex virus 1 inhibits phosphorylation of RNA polymerase II CTD serine-7

Author(s): Adam W. Whisnant, Oliver Dyck Dionisi, Valeria Salazar Sanchez, Julia M. Rappold, Lara Djakovic, Arnhild Grothey, Ana Luiza Marante, Patrick Fischer, Shitao Peng, Katharina Wolf, Thomas Hennig, Lars Dölken
Published in: Journal of Virology, Issue 98, 2024, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.01178-24

The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes

Author(s): Lara Djakovic, Thomas Hennig, Katharina Reinisch, Andrea Milić, Adam W. Whisnant, Katharina Wolf, Elena Weiß, Tobias Haas, Arnhild Grothey, Christopher S. Jürges, Michael Kluge, Elmar Wolf, Florian Erhard, Caroline C. Friedel, Lars Dölken
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-023-40217-W

HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes

Author(s): Elena Weiß, Thomas Hennig, Pilar Graßl, Lara Djakovic, Adam W. Whisnant, Christopher S. Jürges, Franziska Koller, Michael Kluge, Florian Erhard, Lars Dölken, Caroline C. Friedel
Published in: Journal of Virology, Issue 97, 2023, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.00381-23

Time-resolved single-cell RNA-seq using metabolic RNA labelling

Author(s): Florian Erhard, Antoine-Emmanuel Saliba, Alexandra Lusser, Christophe Toussaint, Thomas Hennig, Bhupesh K. Prusty, Daniel Kirschenbaum, Kathleen Abadie, Eric A. Miska, Caroline C. Friedel, Ido Amit, Ronald Micura, Lars Dölken
Published in: Nature Reviews Methods Primers, Issue 2, 2023, ISSN 2662-8449
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S43586-022-00157-Z

Other (1)

Identifying Modulators of Cellular Responses by Heterogeneity-sequencing

Author(s): Kevin Berg, Lygeri Sakellaridi, Teresa Rummel, Thomas Hennig, Adam Whisnant, Manivel Lodha, Tobias Krammer, Bhupesh K Prusty, Lars Dölken, Antoine-Emmanuel Saliba, Florian Erhard
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.28.620481