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TexTOM - X-ray texture tomography as a tool to enable, multi-scale, in-situ imaging of the enthesis, a biological hinge between bone and tendon

Objective

Hierarchical structures are signature elements of many biological and technical materials. The orientational distribution of their crystalline constituents (the crystallographic texture) is important for their mechanical properties. Resolving the local structure and orientation spatially while keeping a large field of view is an unsolved problem. I will solve this by introducing texture tomography, a new 3D x-ray diffraction imaging method, the core of the TexTOM project. It will enable to study the enthesis, the biological connection between tendon and bone, and by in-situ deformation and micromechanical modelling, couple its hierarchical structure with the mechanical behaviour.
I will use the brilliance gain of 4th generation synchrotrons to develop texture tomography as a tool to image complex crystallographic textures in 3D and overcome the spatial resolution barriers of current approaches.
I will develop the reconstruction approach for the crystallographic texture and use it to image the whole enthesis structure with 100nm spatial resolution and, with high energy x-rays, image the enthesis structure during in-situ tensile deformation with µm resolution at several load steps. The unique combination of 3D texture information and loading will allow to build a micromechanical enthesis model.
The novelty lies in the structural 3D characterization of the enthesis under deformation. This is enabled by the development of texture tomography to reconstruct the 3D textures, which will be useful for many other scientific problems. I will build an accurate micromechanical enthesis model and this will shed light on the unknown load transfer mechanism in the enthesis on the nano- and crystal level.
The flexible, open-source approach of TexTOM will ensure adaptation for new users and scientific problems. 4th generation synchrotrons will propel texture tomography to the forefront of (bio)materials science, revolutionizing our study of crystallographic textures.

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution
€ 1 499 694,00
Address
Rue Michel Ange 3
75794 Paris
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00