Dissecting the role of sperm transcriptome dynamics in intergenerational inheritance through native RNA nanopore sequencing

Project Information

EpiSperm

Grant agreement ID: 101042103

DOI

10.3030/101042103

EC signature date 12 July 2022

Start date 1 October 2022

End date 30 September 2027

Funded under

• European Research Council (ERC)

Total cost

€ 1 499 428,00

EU contribution

€ 1 499 428,00

Coordinated by

FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Comprehensive map of ribosomal 2-O-methylation and C/D box snoRNAs in <i>Drosophila melanogaster</i>

Author(s): Athena Sklias; Sonia Cruciani; Virginie Marchand; Mariangela Spagnuolo; Guillaume Lavergne; Valrie Bourguignon; Alessandro Brambilla; Ren Dreos; StevenJ Marygold; EvaMaria Novoa; Yuri Motorin; Jean-Yves Roignant
Published in: Nucleic acids research, Issue vol. 52, no. 6, pp. 2848-2864, 2024, ISSN 1362-4962
Publisher: Oxford Academic
DOI: 10.1093/nar/gkae139

Spectral libraries from nucleobases and deoxyribonucleosides facilitate the identification of ribonucleosides by nanoflow liquid chromatographytandem mass spectrometry

Author(s): Guadalupe Espadas; Laia Llovera; Alexane Ollivier; Francesca Tuorto; Eva Maria Novoa; Eduard Sabid
Published in: Rapid Commun Mass Spectrom, 2024, ISSN 1097-0231
Publisher: Wiley
DOI: 10.1002/rcm.9759

Exploring the epitranscriptome by native RNA sequencing

Author(s): Oguzhan Begik; John S. Mattick; Eva Maria Novoa
Published in: RNA, 2022, ISSN 1469-9001
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.079404.122

The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity, and memory deficits in Down syndrome

Author(s): Cesar Sierra; Miguel Sabariego-Navarro; lvaro Fernndez-Blanco; Sonia Cruciani; Alfonsa Zamora-Moratalla; Eva Maria Novoa; Mara Dierssen
Published in: Mol Psychiatry, 2023, ISSN 1476-5578
Publisher: Springer Nature
DOI: 10.21203/rs.3.rs-3184329/v1

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart

Author(s): Ivan Milenkovic, Helaine Graziele SantosVieira, Morghan C Lucas, Jorge Ruiz-Orera, Giannino Patone, Scott Kesteven, Jianxin Wu, Michael Feneley, Guadalupe Espadas, Eduard Sabid, Norbert Hbner, Sebastiaan vanHeesch, Mirko Vlkers, Eva Maria Novoa
Published in: Nucleic Acids Research, Issue 51, 2023, ISSN 0305-1048
Publisher: Oxford University Press (OUP)
DOI: 10.1093/nar/gkad121

Nature Communications

Author(s): Belinda Baquero-Prez; Ivaylo D. Yonchev; Anna Delgado-Tejedor; Rebeca Medina; Mireia Puig-Torrents; Ian Sudbery; Oguzhan Begik; Stuart A. Wilson; Eva Maria Novoa; Juana Dez
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/2023.10.13.561839

Long-read sequencing in the era of epigenomics and epitranscriptomics

Author(s): Morghan C. Lucas, Eva Maria Novoa
Published in: Nature Methods, Issue 20, 2023, ISSN 1548-7091
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41592-022-01724-8

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

Author(s): Morghan C. Lucas, Leszek P. Pryszcz, Rebeca Medina, Ivan Milenkovic, Noelia Camacho, Virginie Marchand, Yuri Motorin, Lluís Ribas de Pouplana, Eva Maria Novoa
Published in: Nature Biotechnology, Issue 42, 2023, ISSN 1087-0156
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41587-023-01743-6

Elucidation of the Epitranscriptomic RNA Modification Landscape of Chikungunya Virus

Author(s): Belinda Baquero-Prez, Enrico Bortoletto, Umberto Rosani, Anna Delgado-Tejedor, Rebeca Medina, Eva Maria Novoa, Paola Venier, Juana Dez
Published in: Viruses, Issue 16, 2024, ISSN 1999-4915
Publisher: MDPI AG
DOI: 10.3390/v16060945

Nature Methods

Author(s): Oguzhan Begik, Gregor Diensthuber, Huanle Liu, Anna Delgado-Tejedor, Cassandra Kontur, Adnan Muhammad Niazi, Eivind Valen, Antonio J. Giraldez, Jean-Denis Beaudoin, John S. Mattick, Eva Maria Novoa
Published in: Nature Methods, Issue 20, 2023, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-022-01714-w

Other (6)

De novo basecalling of m6A modifications at single molecule and single nucleotide resolution

Author(s): Sonia Cruciani, Anna Delgado-Tejedor, Leszek P. Pryszcz, Rebeca Medina, Laia Llovera, Eva Maria Novoa
Published in: bioRxiv, 2023
Publisher: Cold Spring Harbour

SeqTagger, a rapid and accurate tool to demultiplex direct RNA nanopore sequencing datasets

Author(s): Leszek P Pryszcz, Gregor Diensthuber, Laia Llovera, Rebeca Medina, Anna Delgado-Tejedor, Luca Cozzuto, Julia Ponomarenko, Eva Maria Novoa
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.29.620808

Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures

Author(s): Ivan Milenkovic, Sonia Cruciani, Laia Llovera, Morghan C Lucas, Rebeca Medina, Cornelius Pauli, Daniel Heid, Thomas Muley, Marc A. Schneider, Laura V. Klotz, Michael Allguer, Ruben Lattuca, Denis LJ LaFontaine, Carsten Mller-Tidow, Eva Maria Novoa
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.03.616461

Enhanced detection of RNA modifications and mappability with high-accuracy nanopore RNA basecalling models

Author(s): Gregor Diensthuber, Leszek Pryszcz, Laia Llovera, Morghan C Lucas, Anna Delgado-Tejedor, Sonia Cruciani, Jean-Yves Roignant, Oguzhan Begik, Eva Maria Novoa
Published in: 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.11.28.568965

Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites

Author(s): Anna Delgado-Tejedor; Rebeca Medina; Oguzhan Begik; Luca Cozzuto; Julia Ponomarenko; Eva Maria Novoa
Published in: bioRxiv, 2023, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.03.21.533606

Nanopore Direct RNA Sequencing Data Processing and Analysis Using MasterOfPores

Author(s): Luca Cozzuto, Anna Delgado-Tejedor, Toni Hermoso Pulido, Eva Maria Novoa, Julia Ponomarenko
Published in: Methods in Molecular Biology, Computational Epigenomics and Epitranscriptomics, 2023
Publisher: Springer US
DOI: 10.1007/978-1-0716-2962-8_13