Decoding the path to cellular variation within pathogen populations

Project Information

switchDecoding

Grant agreement ID: 101044320

DOI

10.3030/101044320

EC signature date 19 April 2022

Start date 1 April 2023

End date 31 March 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 999 825,00

EU contribution

€ 1 999 825,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Nature Communications

Author(s): Claudia Rabuffo; Markus R. Schmidt; Prateek Yadav; Pin Tong; Roberta Carloni; Anna Barcons-Simon; Raúl O. Cosentino; Stefan Krebs; Keith R. Matthews; Robin C. Allshire; T. Nicolai Siegel
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/S41467-024-55285-9

Decoding the impact of nuclear organization on antigenic variation in parasites

Author(s): Anna Barcons-Simon; Mark Carrington; T. Nicolai Siegel
Published in: Nature Microbiology, 2023, ISSN 2058-5276
Publisher: Nature Portfolio
DOI: 10.1038/S41564-023-01424-9

Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei

Author(s): Alexander K. Beaver; Zhibek Keneskhanova; Raúl O. Cosentino; Brian L. Weiss; Erick O. Awuoche; Gretchen M. Smallenberger; Gracyn Y. Buenconsejo; Nathan P. Crilly; Jaclyn E. Smith; Jill M. C. Hakim; Bailin Zhang; Bryce Bobb; Filipa Rijo-Ferreira; Luisa M. Figueiredo; Serap Aksoy; T. Nicolai Siegel; Monica R. Mugnier
Published in: Nature, 2024, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/S41586-024-08151-Z

SLAM-seq reveals independent contributions of RNA processing and stability to gene expression in African trypanosomes

Author(s): Vanessa Luzak; Esteban Osses; Anna Danese; Christoff Odendaal; Raúl O Cosentino; Stefan H Stricker; Jurgen R Haanstra; Florian Erhard; T Nicolai Siegel
Published in: Nucleic Acids Research, 2024, ISSN 1362-4962
Publisher: Oxford University Press
DOI: 10.1093/NAR/GKAE1203

Smoother: on-the-fly processing of interactome data using prefix sums

Author(s): Markus R Schmidt; Anna Barcons-Simon; Claudia Rabuffo; T Nicolai Siegel
Published in: Nucleic Acids Research, 2024, ISSN 1362-4962
Publisher: Oxford University Press
DOI: 10.1093/NAR/GKAE008

Genomic determinants of antigen expression hierarchy in African trypanosomes

Author(s): Zhibek Keneskhanova, Kirsty R. McWilliam, Raúl O. Cosentino, Anna Barcons-Simon, Atai Dobrynin, Jaclyn E. Smith, Ines Subota, Monica R. Mugnier, Maria Colomé-Tatché, T. Nicolai Siegel
Published in: Nature, 2025, ISSN 0028-0836
Publisher: Springer Nature
DOI: 10.1038/S41586-025-08720-W