Objective Despite of the successful advances achieved to date in the fight against the COVID-19 pandemic with the development of vaccines and therapy, the worldwide propagation of SARS-CoV-2 has resulted in the rapid evolution of this virus and in the emergence of variants of concern (VOC) that may dampen the efficacy of the first generation vaccines. To tackle the challenges associated with the VOC, the CoVICIS program is proposing a global approach with a powerful state-of-the-art virologic and immunologic platforms coupled with large genomic surveillance studies and diverse cohorts in EU and SSA. This allows CoVICIS to contribute to the early identification of emerging VOC and address key unanswered questions regarding i) the susceptibility to infection with VOC after a prior infection in the setting of a long-COVID or after vaccination with different vaccines, ii) the risk posed by VOC in immunocompromised patients, and iii) the modalities of infection and immune responses in children. The diversity of the cohorts provides a unique opportunity to study virus evolution in different settings, where SARS-CoV-2-specific humoral and cellular immune responses are predicted to vary very significantly. Beyond the genomic surveillance, the ground-breaking research and innovation of the program is the characterization of virologic and immunologic properties of VOC and the identification of immune correlates of protection after disease or vaccination. CoVICIS’ ambitious goals are only achievable thanks to the existing population studies and cohorts funded by national and international public agencies and public-private partnerships, and the combined collective expertise of CoVICIS partners in the fields of epidemiology, genomics, virology, immunology, data science and public health. Fields of science natural sciencesbiological sciencesgeneticsmutationvirus mutationmedical and health sciencesbasic medicineimmunologymedical and health scienceshealth sciencesinfectious diseasesRNA virusescoronavirusesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Keywords Emerging VOC vaccination study long-COVID genomic virologic and immunologic surveillance Programme(s) HORIZON.2.1 - Health Main Programme HORIZON.2.1.4 - Infectious Diseases, including poverty-related and neglected diseases Topic(s) HORIZON-HLTH-2021-CORONA-01-02 - Cohorts united against COVID-19 variants of concern Call for proposal HORIZON-HLTH-2021-CORONA-01 See other projects for this call Funding Scheme HORIZON-RIA - HORIZON Research and Innovation Actions Coordinator CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS Net EU contribution € 1 885 117,00 Address Rue du bugnon 21 1011 Lausanne Switzerland See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,13 Participants (15) Sort alphabetically Sort by Net EU contribution Expand all Collapse all SOUTH AFRICAN MEDICAL RESEARCH COUNCIL South Africa Net EU contribution € 650 000,00 Address Francie van zijl drive - parowvalley 7505 Tygerberg See on map Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France Net EU contribution € 1 003 406,00 Address Rue de tolbiac 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,25 WITS HEALTH CONSORTIUM (PTY) LTD South Africa Net EU contribution € 250 000,00 Address Princess of wales terrace, parktown, 31 2193 Johannesburg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF CAPE TOWN South Africa Net EU contribution € 650 000,00 Address Private bag x3 7701 Rondebosch See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Germany Net EU contribution € 0,00 Address Geschwister scholl platz 1 80539 Muenchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. KLINIKUM DER UNIVERSITAT MUNCHEN Germany Net EU contribution € 560 875,00 Address Marchioninistrasse 15 81377 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE Switzerland Net EU contribution € 700 000,00 Address Batiment ce 3316 station 1 1015 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STIFTUNG SWISS SCHOOL OF PUBLIC HEALTH PLUS (SSPH) Participation ended Switzerland Net EU contribution € 0,00 Address Hirschengraben 82 8001 Zurich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA DEGLI STUDI DI MILANO Italy Net EU contribution € 1 511 016,00 Address Via festa del perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,25 EUROVACC FOUNDATION Switzerland Net EU contribution € 293 750,00 Address Place saint-francois 1 etude kellerhals carrard 1003 Lausanne See on map Region Schweiz/Suisse/Svizzera Région lémanique Vaud Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STICHTING INTERNATIONAL AIDS VACCINE INITIATIVE THE NETHERLANDS Netherlands Net EU contribution € 158 782,00 Address Van diemenstraat 20, 200 unit 48 1013 NH Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 JIMMA UNIVERSITY Ethiopia Net EU contribution € 438 625,00 Address Jimma university Jimma See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STELLENBOSCH UNIVERSITY South Africa Net EU contribution € 450 000,00 Address Victoria street administration b building 7600 Stellenbosch See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,05 UNIVERSITE DE GENEVE Switzerland Net EU contribution € 500 000,00 Address Rue du general dufour 24 1211 Geneve See on map Region Schweiz/Suisse/Svizzera Région lémanique Genève Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT ZURICH Switzerland Net EU contribution € 997 400,00 Address Ramistrasse 71 8006 Zurich See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
