Project description
An AI-based device to prevent epilepsy-derived mortality
Sudden unexpected death in epilepsy (SUDEP) is an important concern for people living with epilepsy. The causes of SUDEP remain unknown while research has so far focused on the cardiac, respiratory, and autonomic nervous systems impairment in patients. The working hypothesis of the EIC-funded NEUROSENSE project is that neuroendocrine processes of epileptic seizures are implicated in SUDEP. It is therefore essential to control seizures to lower SUDEP risk. To achieve this, researchers will develop a device that uses AI to recognise life-threatening seizures and automatically administer drugs in patients to prevent SUDEP
Objective
NEUROSENSE proposes a novel and visionary technology resulting from the demonstration of the upstream role of arousal in the sudden unexpected death in epilepsy (SUDEP). SUDEP is a societal challenge for which there is neither prediction nor prevention. Research in the field has for long been refining classic concepts based on the cardiac, respiratory and autonomic nervous systems impairment. Our vision is different and based on the neuroendocrine processes of epileptic seizures and arousal, which are expected to be impaired in SUDEP. The NEUROSENSE project will develop the first SUDEP Medical Device (SMD) prototype supported by artificial intelligence (AI) to anticipate life-threatening seizures and trigger automatic emergency drug administration to prevent SUDEP. This represents the very first viable solution towards a societal-friendly management of epilepsy-derived mortality, thus enabling the prevention of SUDEP worldwide. This will be achieved through the combination of expertise and innovative ideas in epilepsy and SUDEP, biosensors for medical devices, animal models of epilepsy and SUDEP and mathematical modelling. To tackle the objectives of the NEUROSENSE project, a multidisciplinary group of European leading experts in key technological areas will ensure that the complete chain of value is enclosed in a multifaceted analysis. The high-risk character of this joint science and technology research is offset by the multidisciplinary nature of the Consortium, by strong and extensive preliminary data and by the high socio-economic gain resulting from its successful execution. Based in the new SMD technology, we will build a diverse portfolio of future projects that will result in a long-term benefit for people with epilepsy, their families, the economy and society.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- medical and health sciences basic medicine neurology epilepsy
- social sciences sociology demography mortality
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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HORIZON.3.1.1 - The Pathfinder for Advanced Research
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2021-PATHFINDEROPEN-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4200-135 PORTO
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.