Fluid Biomarkers for Neurodegenerative Dementias

Project Information

FLUBIODEM

Grant agreement ID: 101053962

DOI

10.3030/101053962

EC signature date 4 August 2022

Start date 1 September 2022

End date 31 August 2027

Funded under

• European Research Council (ERC)

Total cost

€ 2 422 973,00

EU contribution

€ 2 422 973,00

Coordinated by

GOETEBORGS UNIVERSITET
Sweden

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Publications

Peer reviewed articles (11)

Synaptic protein CSF levels relate to memory scores in individuals without dementia

Author(s): Kirsten E. J. Wesenhagen, Diederick M. de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Stephanie J. B. Vos, Pablo Martinez-Lage, Mikel Tainta, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Rik Vandenberghe, Yvonne Freund-Levi, Frans Verhey, Simon Lovestone, Johannes Streffer, Valerija Dobricic, Kaj Blennow, Philip Scheltens, August B. Smit, Lars Bertram, Charlotte E. Teunissen, Henrik Zetterberg, Betty M. Tijms, Pieter Jelle Visser, null null
Published in: Alzheimer's Research & Therapy, Issue 17, 2025, ISSN 1758-9193
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13195-025-01703-Z

Hallmarks of neurodegenerative diseases

Author(s): David M. Wilson, Mark R. Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David M. Holtzman, Ilse Dewachter
Published in: Cell, Issue 186, 2023, ISSN 0092-8674
Publisher: Elsevier BV
DOI: 10.1016/J.CELL.2022.12.032

Plasma biomarkers of Alzheimer's disease and related dementias in American Indians: The Strong Heart Study

Author(s): Astrid M. Suchy‐Dicey, W. T. Longstreth, Kristoffer Rhoads, Jason Umans, Dedra Buchwald, Thomas Grabowski, Kaj Blennow, Eric Reiman, Henrik Zetterberg
Published in: Alzheimer's & Dementia, Issue 20, 2024, ISSN 1552-5260
Publisher: Wiley
DOI: 10.1002/ALZ.13664

A comparison of p‐tau assays for the specificity to detect tau changes in Alzheimer's disease

Author(s): Shorena Janelidze, Nicholas J. Ashton, Anna Orduña Dolado, Ulrika Nordström, Divya Bali, Karin M. E. Forsberg, Isil Keskin, Andrea Mastrangelo, Veria Vacchiano, Rocco Liguori, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson‐Carlgren, Fernando Gonzalez‐Ortiz, Piero Parchi, Peter Munch Andersen, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 21, 2025, ISSN 1552-5260
Publisher: Wiley
DOI: 10.1002/ALZ.70208

Acceptability and feasibility of plasma phosphorylated‐tau181 in two memory services

Author(s): Jemma Hazan; Simon Hall; Alex Pemberton; Ian Sherriffs; Suzanne Joels; Amanda Heslegrave; Elena Veleva; Mamoona Ghauri; Rhiannon Laban; Emily Abel; Henrik Zetterberg; Nick C. Fox; Robert Howard
Published in: International Journal of Geriatric Psychiatry, 2023, ISSN 1099-1166
Publisher: John Wiley & Sons Ltd
DOI: 10.1002/GPS.5897

Amyloid is associated with accelerated atrophy in cognitively unimpaired individuals

Author(s): Henry Gilreath Stephenson, Tobey J. Betthauser, Rebecca Langhough, Erin Jonaitis, Lianlian Du, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Nathaniel A. Chin, Ozioma C. Okonkwo, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 17, 2025, ISSN 2352-8729
Publisher: Wiley
DOI: 10.1002/DAD2.70089

Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

Author(s): Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, Yara Yakoub, Julia K. Gundersen, Lene Pålhaugen, Knut Waterloo, Per Selnes, Jonas Alexander Jarholm, Berglind Gísladóttir, Arvid Rongve, Ragnhild Eide Skogseth, Geir Bråthen, Dag Aarsland, Michael Turton, Peter Harrison, Henrik Zetterberg, Sylvia Villeneuve, Tormod Fladby, Kaj Blennow
Published in: Neurology, Issue 104, 2025, ISSN 0028-3878
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1212/WNL.0000000000213676

Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid

Author(s): Francisco J. Meda, Kathryn Knowles, Imogen J. Swift, Aitana Sogorb-Esteve, Jonathan D. Rohrer, Anna Dittrich, Ingmar Skoog, Silke Kern, Bruno Becker, Kaj Blennow, Ulf Andreasson, Hlin Kvartsberg, Henrik Zetterberg
Published in: BMJ Neurology Open, Issue 5, 2024, ISSN 2632-6140
Publisher: BMJ
DOI: 10.1136/BMJNO-2022-000395

Cerebrospinal fluid proteome profiling across the Alzheimer’s disease continuum: a step towards solving the equation for ‘X’

Author(s): Sophia Weiner, Mathias Sauer, Laia Montoliu-Gaya, Andrea L. Benedet, Nicholas J. Ashton, Fernando Gonzalez-Ortiz, Joel Simrén, Nesrine Rahmouni, Cecile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Ville Leinonen, Tuomas Rauramaa, Mikko Hiltunen, Pedro Rosa-Neto, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Published in: Molecular Neurodegeneration, Issue 20, 2025, ISSN 1750-1326
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13024-025-00841-0

Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration

Author(s): Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikari
Published in: Brain, Issue 146, 2023, ISSN 0006-8950
Publisher: Oxford University Press (OUP)
DOI: 10.1093/BRAIN/AWAC407

Applying machine learning to high-dimensional proteomics datasets for the identification of Alzheimer’s disease biomarkers

Author(s): Christoffer Ivarsson Orrelid, Oscar Rosberg, Sophia Weiner, Fredrik D. Johansson, Johan Gobom, Henrik Zetterberg, Newton Mwai, Lena Stempfle
Published in: Fluids and Barriers of the CNS, Issue 22, 2025, ISSN 2045-8118
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12987-025-00634-Z