Fluid Biomarkers for Neurodegenerative Dementias

Informazioni relative al progetto

FLUBIODEM

ID dell’accordo di sovvenzione: 101053962

DOI

10.3030/101053962

Data della firma CE 4 Agosto 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2027

Finanziato da

• European Research Council (ERC)

Costo totale

€ 2 422 973,00

Contributo UE

€ 2 422 973,00

Coordinato da

GOETEBORGS UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Data Management Plan (1)

Data Management Plan

Pubblicazioni

Peer reviewed articles (11)

Synaptic protein CSF levels relate to memory scores in individuals without dementia

Autori: Kirsten E. J. Wesenhagen, Diederick M. de Leeuw, Jori Tomassen, Johan Gobom, Isabelle Bos, Stephanie J. B. Vos, Pablo Martinez-Lage, Mikel Tainta, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Rik Vandenberghe, Yvonne Freund-Levi, Frans Verhey, Simon Lovestone, Johannes Streffer, Valerija Dobricic, Kaj Blennow, Philip Scheltens, August B. Smit, Lars Bertram, Charlotte E. Teunissen, Henrik Zetterberg, Betty M. Tijms, Pieter Jelle Visser, null null
Pubblicato in: Alzheimer's Research & Therapy, Numero 17, 2025, ISSN 1758-9193
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S13195-025-01703-Z

Hallmarks of neurodegenerative diseases

Autori: David M. Wilson, Mark R. Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David M. Holtzman, Ilse Dewachter
Pubblicato in: Cell, Numero 186, 2023, ISSN 0092-8674
Editore: Elsevier BV
DOI: 10.1016/J.CELL.2022.12.032

Plasma biomarkers of Alzheimer's disease and related dementias in American Indians: The Strong Heart Study

Autori: Astrid M. Suchy‐Dicey, W. T. Longstreth, Kristoffer Rhoads, Jason Umans, Dedra Buchwald, Thomas Grabowski, Kaj Blennow, Eric Reiman, Henrik Zetterberg
Pubblicato in: Alzheimer's & Dementia, Numero 20, 2024, ISSN 1552-5260
Editore: Wiley
DOI: 10.1002/ALZ.13664

A comparison of p‐tau assays for the specificity to detect tau changes in Alzheimer's disease

Autori: Shorena Janelidze, Nicholas J. Ashton, Anna Orduña Dolado, Ulrika Nordström, Divya Bali, Karin M. E. Forsberg, Isil Keskin, Andrea Mastrangelo, Veria Vacchiano, Rocco Liguori, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson‐Carlgren, Fernando Gonzalez‐Ortiz, Piero Parchi, Peter Munch Andersen, Oskar Hansson
Pubblicato in: Alzheimer's & Dementia, Numero 21, 2025, ISSN 1552-5260
Editore: Wiley
DOI: 10.1002/ALZ.70208

Acceptability and feasibility of plasma phosphorylated‐tau181 in two memory services

Autori: Jemma Hazan; Simon Hall; Alex Pemberton; Ian Sherriffs; Suzanne Joels; Amanda Heslegrave; Elena Veleva; Mamoona Ghauri; Rhiannon Laban; Emily Abel; Henrik Zetterberg; Nick C. Fox; Robert Howard
Pubblicato in: International Journal of Geriatric Psychiatry, 2023, ISSN 1099-1166
Editore: John Wiley & Sons Ltd
DOI: 10.1002/GPS.5897

Amyloid is associated with accelerated atrophy in cognitively unimpaired individuals

Autori: Henry Gilreath Stephenson, Tobey J. Betthauser, Rebecca Langhough, Erin Jonaitis, Lianlian Du, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Nathaniel A. Chin, Ozioma C. Okonkwo, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson, Kaj Blennow, Henrik Zetterberg, Barbara B. Bendlin
Pubblicato in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Numero 17, 2025, ISSN 2352-8729
Editore: Wiley
DOI: 10.1002/DAD2.70089

Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

Autori: Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, Yara Yakoub, Julia K. Gundersen, Lene Pålhaugen, Knut Waterloo, Per Selnes, Jonas Alexander Jarholm, Berglind Gísladóttir, Arvid Rongve, Ragnhild Eide Skogseth, Geir Bråthen, Dag Aarsland, Michael Turton, Peter Harrison, Henrik Zetterberg, Sylvia Villeneuve, Tormod Fladby, Kaj Blennow
Pubblicato in: Neurology, Numero 104, 2025, ISSN 0028-3878
Editore: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1212/WNL.0000000000213676

Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid

Autori: Francisco J. Meda, Kathryn Knowles, Imogen J. Swift, Aitana Sogorb-Esteve, Jonathan D. Rohrer, Anna Dittrich, Ingmar Skoog, Silke Kern, Bruno Becker, Kaj Blennow, Ulf Andreasson, Hlin Kvartsberg, Henrik Zetterberg
Pubblicato in: BMJ Neurology Open, Numero 5, 2024, ISSN 2632-6140
Editore: BMJ
DOI: 10.1136/BMJNO-2022-000395

Cerebrospinal fluid proteome profiling across the Alzheimer’s disease continuum: a step towards solving the equation for ‘X’

Autori: Sophia Weiner, Mathias Sauer, Laia Montoliu-Gaya, Andrea L. Benedet, Nicholas J. Ashton, Fernando Gonzalez-Ortiz, Joel Simrén, Nesrine Rahmouni, Cecile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Ville Leinonen, Tuomas Rauramaa, Mikko Hiltunen, Pedro Rosa-Neto, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Pubblicato in: Molecular Neurodegeneration, Numero 20, 2025, ISSN 1750-1326
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S13024-025-00841-0

Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration

Autori: Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikari
Pubblicato in: Brain, Numero 146, 2023, ISSN 0006-8950
Editore: Oxford University Press (OUP)
DOI: 10.1093/BRAIN/AWAC407

Applying machine learning to high-dimensional proteomics datasets for the identification of Alzheimer’s disease biomarkers

Autori: Christoffer Ivarsson Orrelid, Oscar Rosberg, Sophia Weiner, Fredrik D. Johansson, Johan Gobom, Henrik Zetterberg, Newton Mwai, Lena Stempfle
Pubblicato in: Fluids and Barriers of the CNS, Numero 22, 2025, ISSN 2045-8118
Editore: Springer Science and Business Media LLC
DOI: 10.1186/S12987-025-00634-Z