HLA-homozygous iPSC-cardiomyocytE Aggregate manufacturing technoLogies for allogenic cell therapy to the heart

Project Information

HEAL

Grant agreement ID: 101056712

DOI 10.3030/101056712

EC signature date 23 May 2022

Start date 1 September 2022

End date 28 February 2026

Funded under

• Health

Total cost € 5 824 075,00

EU contribution € 5 824 074,00

Coordinated by

MEDIZINISCHE HOCHSCHULE HANNOVER
Germany

Deliverables

Websites, patent fillings, videos etc. (1)

Launch of project website

D6.2Launch of project website

Publications

Peer reviewed articles (5)

Abstract 23 HLA-Homozygous iPSC from Cord Blood for the Generation of Cardiomyocytes for Allogeneic Cell Therapy to the Heart

Author(s): Fabienne Becker, Stefanie Liedtke, Boris Greber, Nils Kriedemann, Ulrich Martin, Robert Zweigerdt, Gesine Kögler
Published in: Stem Cells Translational Medicine, 2023, ISSN 2157-6564
Publisher: STEM CELLS Translatinal Medicine
DOI: 10.1093/stcltm/szad047.024

High prevalence of acquired cancer-related mutations in 146 human pluripotent stem cell lines and their differentiated derivatives

Author(s): Lezmi, E.; Jung, J.; Benvenisty, N.
Published in: Nature Biotechnology, 2024, ISSN 1546-1696
Publisher: Springer Nature
DOI: 10.1038/s41587-023-02090-2

EpiTyping: analysis of epigenetic aberrations in parental imprinting and X-chromosome inactivation using RNA-seq

Author(s): Sarel-Gallily,R.; Keshet, G.; Benvenisty, N.
Published in: Nature Protocols, Issue 18, 2023, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-023-00898-5

Advances in extracellular vesicle research over the past decade: Source and isolation method are connected with cargo and function

Author(s): Rodolphe Poupardin, Martin Wolf, Nicole Maeding, Liliia Paniushkina, Sven Geissler, Paolo Bergese, Kenneth W Witwer, Katharina Schallmoser, Gregor Fuhrmann, Dirk Strunk
Published in: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Publisher: Wiley
DOI: 10.1002/adhm.202303941

Cell therapy with human iPSC-derived cardiomyocyte aggregates leads to efficient engraftment and functional recovery after myocardial infarction in non-human

Author(s): Ina Gruh, Andreas Martens, Serghei Cebotari, Annette Schrod, Alexandra Haase, Caroline Halloin, Wiebke Triebert, Tobias Goecke, Morsi Arar, Klaus Hoeffler, Paul Frank, Karen Lampe, Amir Moussavi, Veronika Fricke, Nils Kriedemann, Monika Szepes, Kerstin Mä
Published in: bioRxiv, 2024, ISSN 1231-5737
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.12.31.573775