HLA-homozygous iPSC-cardiomyocytE Aggregate manufacturing technoLogies for allogenic cell therapy to the heart

Informazioni relative al progetto

HEAL

ID dell’accordo di sovvenzione: 101056712

DOI 10.3030/101056712

Data della firma CE 23 Maggio 2022

Data di avvio 1 Settembre 2022

Data di completamento 28 Febbraio 2026

Finanziato da

• Health

Costo totale € 5 824 075,00

Contributo UE € 5 824 074,00

Coordinato da

MEDIZINISCHE HOCHSCHULE HANNOVER
Germany

Risultati finali

Websites, patent fillings, videos etc. (1)

Launch of project website

D6.2Launch of project website

Pubblicazioni

Peer reviewed articles (5)

Abstract 23 HLA-Homozygous iPSC from Cord Blood for the Generation of Cardiomyocytes for Allogeneic Cell Therapy to the Heart

Autori: Fabienne Becker, Stefanie Liedtke, Boris Greber, Nils Kriedemann, Ulrich Martin, Robert Zweigerdt, Gesine Kögler
Pubblicato in: Stem Cells Translational Medicine, 2023, ISSN 2157-6564
Editore: STEM CELLS Translatinal Medicine
DOI: 10.1093/stcltm/szad047.024

High prevalence of acquired cancer-related mutations in 146 human pluripotent stem cell lines and their differentiated derivatives

Autori: Lezmi, E.; Jung, J.; Benvenisty, N.
Pubblicato in: Nature Biotechnology, 2024, ISSN 1546-1696
Editore: Springer Nature
DOI: 10.1038/s41587-023-02090-2

EpiTyping: analysis of epigenetic aberrations in parental imprinting and X-chromosome inactivation using RNA-seq

Autori: Sarel-Gallily,R.; Keshet, G.; Benvenisty, N.
Pubblicato in: Nature Protocols, Numero 18, 2023, ISSN 1754-2189
Editore: Nature Publishing Group
DOI: 10.1038/s41596-023-00898-5

Advances in extracellular vesicle research over the past decade: Source and isolation method are connected with cargo and function

Autori: Rodolphe Poupardin, Martin Wolf, Nicole Maeding, Liliia Paniushkina, Sven Geissler, Paolo Bergese, Kenneth W Witwer, Katharina Schallmoser, Gregor Fuhrmann, Dirk Strunk
Pubblicato in: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Editore: Wiley
DOI: 10.1002/adhm.202303941

Cell therapy with human iPSC-derived cardiomyocyte aggregates leads to efficient engraftment and functional recovery after myocardial infarction in non-human

Autori: Ina Gruh, Andreas Martens, Serghei Cebotari, Annette Schrod, Alexandra Haase, Caroline Halloin, Wiebke Triebert, Tobias Goecke, Morsi Arar, Klaus Hoeffler, Paul Frank, Karen Lampe, Amir Moussavi, Veronika Fricke, Nils Kriedemann, Monika Szepes, Kerstin Mä
Pubblicato in: bioRxiv, 2024, ISSN 1231-5737
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.12.31.573775