Risk and Resilience in Developmental Diversity and Mental Health

Project Information

R2D2-MH

Grant agreement ID: 101057385

DOI

10.3030/101057385

EC signature date 23 May 2022

Start date 1 September 2022

End date 31 August 2027

Funded under

• Health

Total cost

€ 8 456 507,50

EU contribution

€ 8 456 503,75

Coordinated by

INSTITUT PASTEUR
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Dissemination and Communication Plan

Dissemination and Communication PlanTo be updated regularly

R2D2-MH Data Management Plan

Websites, patent fillings, videos etc. (2)

R2D2-MH Website
R2D2-MH Online information and training platform

Publications

Peer reviewed articles (40)

Breastfeeding Duration and Child Development

Author(s): Inbal Goldshtein; Yair Sadaka; Guy Amit; Nitsa Kasir; Thomas Bourgeron; Varun Warrier; Pinchas Akiva; Meytal Avgil Tsadok; Deena R. Zimmerman
Published in: JAMA Network Open, 2025, ISSN 2574-3805
Publisher: JAMA
DOI: 10.1001/JAMANETWORKOPEN.2025.1540

Associations between early language, motor abilities, and later autism traits in infants with typical and elevated likelihood of autism

Author(s): Leyan Li; Greg Pasco; Jannath Begum Ali; Mark H. Johnson; Emily J. H. Jones; Tony Charman
Published in: Autism Research, 2023, ISSN 1939-3806
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/aur.3023

Socioeconomic outcomes in very preterm/very low birth weight adults: individual participant data meta-analysis

Author(s): Yanlin Zhou, Marina Mendonça, Nicole Tsalacopoulos, Peter Bartmann, Brian A. Darlow, Sarah L. Harris, John Horwood, Lianne J. Woodward, Peter J. Anderson, Lex W. Doyle, Jeanie L. Y. Cheong, Eero Kajantie, Marjaana Tikanmäki, Samantha Johnson, Neil Marlow, Chiara Nosarti, Marit S. Indredavik, Kari Anne I. Evensen, Katri Räikkönen, Kati Heinonen, Sylvia van der Pal, Dieter Wolke
Published in: Pediatric Research, 2025, ISSN 0031-3998
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41390-025-04082-1

High level of immunoglobulin G targeting mycoplasma or cytomegalovirus in the newborn increases risk of ADHD

Author(s): Nis Borbye-Lorenzen, Solveig Holmgaard, Filip Ottosson, Ron Nudel, Vivek Appadurai, Thomas Munk Laursen, Marie Bækvad-Hansen, Jonas Bybjerg-Grauholm, Merete Nordentoft, Anders D Børglum, Preben Bo Mortensen, Thomas Werge, Michael E Benros, David Michael Hougaard, Kristin Skogstrand
Published in: Brain, Behavior, and Immunity, Issue 123, 2025, ISSN 0889-1591
Publisher: Elsevier BV
DOI: 10.1016/J.BBI.2024.09.009

Phenotypic effects of genetic variants associated with autism

Author(s): Thomas Rolland; Freddy Cliquet; Richard J. L. Anney; Clara Moreau; Nicolas Traut; Alexandre Mathieu; Guillaume Huguet; Jinjie Duan; Varun Warrier; Swan Portalier; Louise Dry; Claire S. Leblond; Elise Douard; Frédérique Amsellem; Simon Malesys; Anna Maruani; Roberto Toro; Anders D. Børglum; Jakob Grove; Simon Baron-Cohen; Alan Packer; Wendy K. Chung; Sébastien Jacquemont; Richard Delorme; Thomas Bourgeron
Published in: "Nature Medicine, 2023, ⟨10.1038/s41591-023-02408-2⟩", 2023, ISSN 1546-170X
Publisher: Nature portfolio
DOI: 10.1038/s41591-023-02408-2

Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses

Author(s): Trine Tollerup Nielsen, Paraskevi Bali, Jakob Grove, Christina Mohr-Jensen, Thomas Werge, Søren Dalsgaard, Anders D. Børglum, Edmund Sonuga-Barke, Helen Minnis, Ditte Demontis, null null, Elizabeth C. Corfield, Ludger Tbartz van Elst, Manuel Mattheisen, Melanie M. de Wit, Mohammed Jashim Uddin, Richard J. L. Anney, Stephen W. Scherer, Thomas Bourgeron, Tinca J. C. Polderman
Published in: JAMA Psychiatry, Issue 82, 2025, ISSN 2168-622X
Publisher: American Medical Association (AMA)
DOI: 10.1001/JAMAPSYCHIATRY.2025.0828

Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD

Author(s): Trine Tollerup Nielsen, Jinjie Duan, Daniel F. Levey, G. Bragi Walters, Emma C. Johnson, Thorgeir Thorgeirsson, null null, Daniel F. Levey, Joel Gelernter, Thomas Werge, Preben Bo Mortensen, Hreinn Stefansson, Kari Stefansson, David M. Hougaard, Arpana Agrawal, Joel Gelernter, Jakob Grove, Anders D. Børglum, Ditte Demontis
Published in: Nature Mental Health, Issue 2, 2024, ISSN 2731-6076
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44220-024-00277-3

Fostering positive mental health outcomes in vulnerable children: Pathways to resilience after preterm birth

Author(s): E. Sabrina Twilhaar, Dieter Wolke
Published in: Journal of Child Psychology and Psychiatry, 2025, ISSN 0021-9630
Publisher: Wiley
DOI: 10.1111/JCPP.70002

Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity

Author(s): Lucía de Hoyos, Ellen Verhoef, Aysu Okbay, Janne R. Vermeulen, Celeste Figaroa, Miriam Lense, Simon E. Fisher, Reyna L. Gordon, Beate St Pourcain
Published in: npj Science of Learning, Issue 10, 2025, ISSN 2056-7936
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41539-025-00329-Y

Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics

Author(s): Christine Ecker, Charlotte M. Pretzsch, Johanna Leyhausen, Lisa M. Berg, Caroline Gurr, Hanna Seelemeyer, Grainne McAlonan, Nicolaas A. Puts, Eva Loth, Flavio Dell’Aqua, Luke Mason, Tony Charman, Bethany Oakley, Thomas Bourgeron, Christian Beckmann, Jan K. Buitelaar, Celso Arango, Tobias Banaschewski, Andreas G. Chiocchetti, Christine M. Freitag, Elke Hattingen, Dilja Krueger-Burg, Michael J. Schmeisser, Jonathan Repple, Andreas Reif, Declan G. Murphy
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-61927-3

Parent–child similarity on autism and <scp>ADHD</scp> traits and children's social functioning and psychological well‐being at 3 years

Author(s): Daniel L. Wechsler, Emily J. H. Jones, Greg Pasco, Tessel Bazelmans, Jannath Begum‐Ali, Mark H. Johnson, Tony Charman, null null
Published in: Journal of Child Psychology and Psychiatry, 2025, ISSN 0021-9630
Publisher: Wiley
DOI: 10.1111/JCPP.70014

From Symptomatology to Functioning - Applying the ICF to Autism Measures to Facilitate Neurodiversity-Affirmative Data Harmonization

Author(s): Black, M.H., Remnélius, K.L., Alehagen, L. et al.
Published in: J Autism Dev Disord, 2025, ISSN 1573-3432
Publisher: Springer
DOI: 10.1007/S10803-023-06204-2

Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Author(s): Yuanjun Gu; Eva Maria-Stauffer; Saashi A. Bedford; Deep Adhya; Carrie Allison; Bonnie Ayeung; Rosie Bamford; Richard Bethlehem; Tal Biron-Shental; Graham Burton; Jonathan Davies; Joanna Davis; Dori Floris; Alice Franklin; Lidia Gabis; Daniel Geschwind; David M. Greenberg; Alexandra Havdahl; Alexander Heazell; Rosemary Holt; Matthew Hurles; Yumnah Khan; Meng-Chuan Lai; Madeline Lancaster; Michael Lombardo; Jose Gonzalez Martinez; Jonathan Mill; Mahmoud Koko Musa; Kathy Niakan; Adam Pavlinek; Lucia Dutan Polit; Marcin Radecki; David Rowitch; Laura Sichlinger; Deepak Srivastava; Alexandros Tsompanidis; Florina Uzefovsky; Elizabeth Weir; Xinhe Zhang; Anders Borglum; Jonas Bybjerg-Grauholm; David M. Hougaard; Ole Mors; Preben Bo Mortensen; Merete Nordentoft; Thomas Werge; Rafael Romero-Garcia; Jakob Grove; Anders D. Børglum; Hilary Martin; Simon Baron-Cohen; Richard A. I. Bethlehem; Varun Warrier
Published in: Molecular Psychiatry, 2025, ISSN 1476-5578
Publisher: Nature
DOI: 10.17863/CAM.116118

Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders

Author(s): Strom, Nora I.; Halvorsen, Matthew W.; Grove, Jakob; Ásbjörnsdóttir, Bergrún; Luðvígsson, Pétur; Thorarensen, Ólafur; de Schipper, Elles; Bäckmann, Julia; Andrén, Per; Tian, Chao; Yu, Dongmei; Sul, Jae Hoon; Tsetsos, Fotis; Nawaz, Muhammad S.; Huang, Alden Y.; Zelaya, Ivette; Illmann, Cornelia; Osiecki, Lisa; Darrow, Sabrina M.; Hirschtritt, Matthew E.; Greenberg, Erica; Muller-Vahl, Kirsten R.; Stuhrmann, Manfred; Dion, Yves; Rouleau, Guy; Aschauer, Harald; Stamenkovic, Mara; Schlögelhofer, Monika; Sandor, Paul; Barr, Cathy L.; Grados, Marco; Singer, Harvey S.; Nöthen, Markus M.; Hebebrand, Johannes; Hinney, Anke; King, Robert A.; Fernandez, Thomas V.; Barta, Csaba; Tarnok, Zsanett; Nagy, Peter; Depienne, Christel; Worbe, Yulia; Hartmann, Andreas; Budman, Cathy L.; Rizzo, Renata; Lyon, Gholson J.; McMahon, William M.; Batterson, James R.; Cath, Danielle C.; Malaty, Irene A.; Okun, Michael S.; Berlin, Cheston; Woods, Douglas W.; Lee, Paul C.; Jankovic, Joseph; Robertson, Mary M.; Gilbert, Donald L.; Brown, Lawrence W.; Coffey, Barbara J.; Dietrich, Andrea; Hoekstra, Pieter J.; Kuperman, Samuel; Zinner, Samuel H.; Luðvigsson, Pétur; Sæmundsen, Evald; Thorarensen, Ólafur; Atzmon, Gil; Barzilai, Nir; Wagner, Michael; Moessner, Rainald; Ophoff, Roel; Pato, Carlos N.; Pato, Michele T.; Knowles, James A.; Roffman, Joshua L.; Smoller, Jordan W.; Buckner, Randy L.; Willsey, Jeremy A.; Tischfield, Jay A.; Heiman, Gary A.; Stefansson, Hreinn; Stefansson, Kári; Posthuma, Danielle; Cox, Nancy J.; Pauls, David L.; Freimer, Nelson B.; Neale, Benjamin M.; Davis, Lea K.; Paschou, Peristera; Coppola, Giovanni; Mathews, Carol A.; Scharf, Jeremiah M.; Agee, Michelle; Auton, Adam; Bell, Robert K.; Bryc, Katarzyna; Elson, Sarah L.; Fontanillas, Pierre; Furlotte, Nicholas A.; Hicks, Barry; Huber, Karen E.; Jewett, Ethan M.; Jiang, Yunxuan; Kleinman, Aaron; Lin, Keng-Han; Litterman, Nadia K.; McCreight, Jey C.; McIntyre, Matthew H.; McManus, Kimberly F.; Mountain, Joanna L.; Noblin, Elizabeth S.; Northover, Carrie A. M.; Pitts, Steven J.; Poznik, G. David; Sathirapongsasuti, J. Fah; Shelton, Janie F.; Shringarpure, Suyash; Tung, Joyce Y.; Vacic, Vladimir; Wang, Xin; Als, Thomas Damm; Nissen, Judith Becker; Meier, Sandra M.; Bybjerg-Grauholm, Jonas; Hougaard, David M.; Werge, Thomas; Børglum, Anders D.; Hinds, David A.; Rück, Christian; Mataix-Cols, David; Stefánsson, Hreinn; Stefansson, Kari; Crowley, James J.; Mattheisen, Manuel
Published in: Biological Psychiatry, 2024, ISSN 1873-2402
Publisher: Elsevier
DOI: 10.1016/J.BIOPSYCH.2024.07.025

Effectiveness of a positive psychology and mindfulness-based app on mental health for parents of children with a neurodevelopmental disorder: study protocol of a pragmatic international randomized controlled trial

Author(s): Kim J. M. Tönis, Constance H. C. Drossaert, Peter M. ten Klooster, Marie Schaer, Thomas Bourgeron, Jan K. Buitelaar, Yair Sadaka, Christine M. Freitag, Keren Mayer Lapidus, Andreas G. Chiocchetti, Wouter G. Staal, Ernst T. Bohlmeijer
Published in: Trials, Issue 25, 2024, ISSN 1745-6215
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13063-024-08256-W

Risk and resilience in developmental diversity: Protocol of developing ICF core sets

Author(s): Melissa H. Black; Leni Van Goidsenhoven; Kristien Hens; Thomas Bourgeron; Sven Bölte
Published in: Neurodiversity, 2023, ISSN 1573-3432
Publisher: Springer
DOI: 10.1177/27546330231190235

Application of the international classification of functioning, disability, and health in autism and attention-deficit hyperactivity disorder: A scoping review

Author(s): Lovisa Alehagen; Sven Bölte; Melissa H Black
Published in: Autism, 2024, ISSN 1461-7005
Publisher: Sage
DOI: 10.1177/13623613241272044

The neuroanatomical substrates of autism and ADHD and their link to putative genomic underpinnings

Author(s): Berg, L.M., Gurr, C., Leyhausen, J. et al.
Published in: Molecular Autism, 2023, ISSN 2040-2392
Publisher: BioMed Central
DOI: 10.1186/s13229-023-00568-z

Harmonizing Big Data in Mental Health Research: A Proof-of-Principle in the R2D2-MH Consortium Using the International Classification of Functioning (ICF)

Author(s): Melissa Black; Jan Buitelaar; Tony Charman; Christine Ecker; Louise Gallagher; Kristien Hens; Emily Jones; Declan Murphy; Marie Schaer; Yair Sadaka; Beate St-Pourcain; Dieter Wolke; Stéf Bonnot-Briey; Thomas Bougeron; Sven Bölte
Published in: Crossref, 2023, ISSN 2693-5015
Publisher: Research Square
DOI: 10.21203/RS.3.RS-3672113/V1

From cells to selves and back: human neurodiversity at single cell resolution

Author(s): Manuel Lessi, Nicolò Caporale, Giuseppe Testa
Published in: Physiology, 2025, ISSN 1548-9213
Publisher: American Physiological Society
DOI: 10.1152/PHYSIOL.00010.2025

Developmental diversity: Putting the development back into research about developmental conditions

Author(s): Kristien, Hens; Leni, Van Goidsenhoven
Published in: 1664-0640, 2023, ISSN 1664-0640
Publisher: frontiers
DOI: 10.3389/fpsyt.2022.986732

Patterns of Brain Maturation in Autism and Their Molecular Associations

Author(s): Charlotte M. Pretzsch; Martina Arenella; Jason P. Lerch; Michael V. Lombardo; Christian Beckmann; Tim Schaefer; Johanna Leyhausen; Caroline Gurr; Anke Bletsch; Lisa M. Berg; Hanna Seelemeyer; Dorothea L. Floris; Bethany Oakley; Eva Loth; Thomas Bourgeron; Tony Charman; Jan Buitelaar; Grainne McAlonan; Declan Murphy; Christine Ecker; Jumana Ahmad; Sara Ambrosino; Bonnie Auyeung; Tobias Banaschewski; Simon Baron-Cohen; Sarah Baumeister; Christian F. Beckmann; Sven Bölte; Thomas Bourgeron; Carsten Bours; Michael Brammer; Daniel Brandeis; Claudia Brogna; Yvette de Bruijn; Jan K. Buitelaar; Bhismadev Chakrabarti; Tony Charman; Ineke Cornelissen; Daisy Crawley; Flavio Dell'Acqua; Guillaume Dumas; Sarah Durston; Christine Ecker; Jessica Faulkner; Vincent Frouin; Pilar Garcés; David Goyard; Lindsay Ham; Hannah Hayward; Joerg Hipp; Rosemary Holt; Mark H. Johnson; Emily J.H. Jones; Prantik Kundu; Meng-Chuan Lai; Xavier Liogier D'Ardhuy; Michael V. Lombardo; Eva Loth; David J. Lythgoe; René Mandl; Andre Marquand; Luke Mason; Maarten Mennes; Andreas Meyer-Lindenberg; Carolin Moessnang; Nico Mueller; Declan GM Murphy; Bethany Oakley; Laurence O'Dwyer; Marianne Oldehinkel; Bob Oranje; Gahan Pandina; Antonio M. Persico; Barbara Ruggeri; Amber Ruigrok; Jessica Sabet; Roberto Sacco; Antonia San José Cáceres; Emily Simonoff; Will Spooren; Julian Tillmann; Roberto Toro; Heike Tost; Jack Waldman; Steve CR Williams; Caroline Wooldridge; Marcel Zwiers
Published in: JAMA Psychiatry, 2024, ISSN 2168-6238
Publisher: JAMA
DOI: 10.1001/JAMAPSYCHIATRY.2024.3194

More Than a Lick of Paint. State Neuro-Neutrality Requires Structural Social Change

Author(s): Emma Moormann, Gert-Jan Vanaken
Published in: AJOB Neuroscience, Issue 15, 2025, ISSN 2150-7740
Publisher: Informa UK Limited
DOI: 10.1080/21507740.2024.2402222

Advancing health-care equity for autistic people: mental health as a key priority

Author(s): Daniel L Wechsler, William Mandy, Meng-Chuan Lai, Brian Boyd, Matthew S Goodwin, Gauri Divan, Virginia Carter Leno
Published in: The Lancet, Issue 405, 2025, ISSN 0140-6736
Publisher: Elsevier BV
DOI: 10.1016/S0140-6736(25)00667-1

A systematic review of conceptualizations and statistical methods in longitudinal studies of resilience

Author(s): Dieter Wolke, Yanlin Zhou, Yiwen Liu, Robert Eves, Marina Mendonça, E. Sabrina Twilhaar
Published in: Nature Mental Health, Issue 3, 2025, ISSN 2731-6076
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S44220-025-00479-3

Resilience in the face of neurodivergence: A scoping review of resilience and factors promoting positive outcomes

Author(s): Black, Melissa H.; Helander, Johan; Segers, Julie; Ingard, Cecilia; Bervoets, Jo; de Puget, Vincent Grimaldi; Bölte, Sven
Published in: Clinical Psychology Review, 2024, ISSN 1873-7811
Publisher: Elsevier
DOI: 10.1016/J.CPR.2024.102487

Conceptual framework for data harmonisation in mental health using the International Classification of Functioning, Disability and Health: an example with the R2D2-MH consortium

Author(s): Melissa H Black; Jan Buitelaar; Tony Charman; Christine Ecker; Louise Gallagher; Kristien Hens; Emily Jones; Declan Murphy; Yair Sadaka; Marie Schaer; Beate St Pourcain; Dieter Wolke; Stef Bonnot-Briey; Thomas Bourgeron; Sven Bölte
Published in: BMJ Mental Health, 2024, ISSN 2755-9734
Publisher: BMJ
DOI: 10.1136/BMJMENT-2024-301283

Developmental trajectories of internalizing problems among individuals born very preterm/very low birthweight: early risk and resilience factors

Author(s): Yanlin Zhou, Peter Bartmann, Nicole Tsalacopoulos, Dieter Wolke
Published in: European Child &amp; Adolescent Psychiatry, 2025, ISSN 1018-8827
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S00787-025-02736-3

Developmental trajectories of internalizing problems among individuals born very preterm/very low birthweight: early risk and resilience factors

Author(s): Yanlin Zhou, Peter Bartmann, Nicole Tsalacopoulos, Dieter Wolke
Published in: European Child &amp; Adolescent Psychiatry, 2025, ISSN 1018-8827
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/S00787-025-02736-3

Early prediction of autistic spectrum disorder using developmental surveillance data

Author(s): Guy Amit, Yonatan Bilu, Tamar Sudry, Meytal Avgil Tsadok, Deena R. Zimmerman, Ravit Baruch, Nitsa Kasir, Pinchas Akiva, Yair Sadaka
Published in: JAMA Network Open, Issue 7, 1, 2024, ISSN 2574-3805
Publisher: Jama network
DOI: 10.1001/jamanetworkopen.2023.51052

Twenty‐four‐month effortful control predicts emerging autism characteristics

Author(s): Roisin C. Perry, Mark H. Johnson, Tony Charman, Greg Pascoe, Andrew Tolmie, Michael S. C. Thomas, Iroise Dumontheil, Emily J. H. Jones, null null
Published in: Developmental Science, Issue 27, 2025, ISSN 1363-755X
Publisher: Wiley
DOI: 10.1111/DESC.13560

Child Hyperactivity, Mother–Child Negativity, and Sibling Dyad Negativity: A Transactional Family Systems Approach

Author(s): Slava Dantchev, Dieter Wolke, Martina Zemp
Published in: J. Fam. Psychol, 2024, ISSN 0893-3200
Publisher: American Psychological Association
DOI: 10.1037/FAM0001090

A Genetic Bridge Between Medicine and Neurodiversity for Autism

Author(s): Claire S. Leblond, Thomas Rolland, Eli Barthome, Zakaria Mougin, Mathis Fleury, Christine Ecker, Stéf Bonnot-Briey, Freddy Cliquet, Anne-Claude Tabet, Anna Maruani, Boris Chaumette, Jonathan Green, Richard Delorme, and Thomas Bourgeron
Published in: Annual Reviews, 2024, ISSN 1545-2948
Publisher: Annual Reviews
DOI: 10.1146/ANNUREV-GENET-111523-102614

Population-Based Risk of Psychiatric Disorders Associated With Recurrent Copy Number Variants

Author(s): Morteza Vaez; Simone Montalbano; Xabier Calle Sánchez; Kajsa-Lotta Georgii Hellberg; Saeid Rasekhi Dehkordi; Morten Dybdahl Krebs; Joeri Meijsen; John Shorter; Jonas Bybjerg-Grauholm; Preben B. Mortensen; Anders D. Børglum; David M. Hougaard; Merete Nordentoft; Daniel H. Geschwind; Alfonso Buil; Andrew J. Schork; Dorte Helenius; Armin Raznahan; Wesley K. Thompson; Thomas Werge; Andrés Ingason; Anders D. Børglum; David M. Hougaard; Merete Nordentoft; Ole Mors; Preben B. Mortensen; Thomas Werge; Jakob Grove; Thomas D. Als; Alfonso Buil; Anders Rosengren; Andrés Ingason; Andrew J. Schork; Dorte Helenius; Jesper Gådin; Richard Zetterberg; Vivek Appadurai; Joeri Meijsen; Kajsa-Lotta Georgii Hellberg; Bjarni J. Vilhjálmsson; Carsten B. Pedersen; Esben Agerbo; Jakob Christensen; Liselotte V. Petersen; Marianne Gjørtz Pedersen; Jonas Byberg-Grauholm; Marie Bækvad-Hansen
Published in: JAMA Psychiatry, 2024, ISSN 2168-6238
Publisher: JAMA
DOI: 10.1001/JAMAPSYCHIATRY.2024.1453

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Author(s): Nora I. Strom, Zachary F. Gerring, Marco Galimberti, Dongmei Yu, Matthew W. Halvorsen, Abdel Abdellaoui, Cristina Rodriguez-Fontenla, Julia M. Sealock, Tim Bigdeli, Jonathan R. Coleman, Behrang Mahjani, Jackson G. Thorp, Katharina Bey, Christie L. Burton, Jurjen J. Luykx, Gwyneth Zai, Silvia Alemany, Christine Andre, Kathleen D. Askland, Julia Bäckman, Nerisa Banaj, Cristina Barlassina, Judith Becker Nissen, O. Joseph Bienvenu, Donald Black, Michael H. Bloch, Sigrid Børte, Rosa Bosch, Michael Breen, Brian P. Brennan, Helena Brentani, Joseph D. Buxbaum, Jonas Bybjerg-Grauholm, Enda M. Byrne, Judit Cabana-Dominguez, Beatriz Camarena, Adrian Camarena, Carolina Cappi, Angel Carracedo, Miguel Casas, Maria Cristina Cavallini, Valentina Ciullo, Edwin H. Cook, Jesse Crosby, Bernadette A. Cullen, Elles J. De Schipper, Richard Delorme, Srdjan Djurovic, Jason A. Elias, Xavier Estivill, Martha J. Falkenstein, Bengt T. Fundin, Lauryn Garner, Christina Gironda, Fernando S. Goes, Marco A. Grados, Jakob Grove, Wei Guo, Jan Haavik, Kristen Hagen, Kelly Harrington, Alexandra Havdahl, Kira D. Höffler, Ana G. Hounie, Donald Hucks, Christina Hultman, Magdalena Janecka, Eric Jenike, Elinor K. Karlsson, Kara Kelley, Julia Klawohn, Janice E. Krasnow, Kristi Krebs, Christoph Lange, Nuria Lanzagorta, Daniel Levey, Kerstin Lindblad-Toh, Fabio Macciardi, Brion Maher, Brittany Mathes, Evonne McArthur, Nathaniel McGregor, Nicole C. McLaughlin, Sandra Meier, Euripedes C. Miguel, Maureen Mulhern, Paul S. Nestadt, Erika L. Nurmi, Kevin S. O’Connell, Lisa Osiecki, Olga Therese Ousdal, Teemu Palviainen, Nancy L. Pedersen, Fabrizio Piras, Federica Piras, Sriramya Potluri, Raquel Rabionet, Alfredo Ramirez, Scott Rauch, Abraham Reichenberg, Mark A. Riddle, Stephan Ripke, Maria C. Rosário, Aline S. Sampaio, Miriam A. Schiele, Anne Heidi Skogholt, Laura G. Sloofman, Jan Smit, María Soler Artigas, Laurent F. Thomas, Eric Tifft, Homero Vallada, Nathanial van Kirk, Jeremy Veenstra-VanderWeele, Nienke N. Vulink, Christopher P. Walker, Ying Wang, Jens R. Wendland, Bendik S. Winsvold, Yin Yao, Hang Zhou, null null, Andres Metspalu, Tõnu Esko, Reedik Mägi, Mari Nelis, Georgi Hudjashov, null null, Chris German, Arpana Agrawal, Pino Alonso, Götz Berberich, Kathleen K. Bucholz, Cynthia M. Bulik, Danielle Cath, Damiaan Denys, Valsamma Eapen, Howard Edenberg, Peter Falkai, Thomas V. Fernandez, Abby J. Fyer, J. M. Gaziano, Dan A. Geller, Hans J. Grabe, Benjamin D. Greenberg, Gregory L. Hanna, Ian B. Hickie, David M. Hougaard, Norbert Kathmann, James Kennedy, Dongbing Lai, Mikael Landén, Stéphanie Le Hellard, Marion Leboyer, Christine Lochner, James T. McCracken, Sarah E. Medland, Preben B. Mortensen, Benjamin M. Neale, Humberto Nicolini, Merete Nordentoft, Michele Pato, Carlos Pato, David L. Pauls, John Piacentini, Christopher Pittenger, Danielle Posthuma, Josep Antoni Ramos-Quiroga, Steven A. Rasmussen, Margaret A. Richter, David R. Rosenberg, Stephan Ruhrmann, Jack F. Samuels, Sven Sandin, Paul Sandor, Gianfranco Spalletta, Dan J. Stein, S. Evelyn Stewart, Eric A. Storch, Barbara E. Stranger, Maurizio Turiel, Thomas Werge, Ole A. Andreassen, Anders D. Børglum, Susanne Walitza, Kristian Hveem, Bjarne K. Hansen, Christian Rück, Nicholas G. Martin, Lili Milani, Ole Mors, Ted Reichborn-Kjennerud, Marta Ribasés, Gerd Kvale, David Mataix-Cols, Katharina Domschke, Edna Grünblatt, Michael Wagner, John-Anker Zwart, Gerome Breen, Gerald Nestadt, Jaakko Kaprio, Paul D. Arnold, Dorothy E. Grice, James A. Knowles, Helga Ask, Karin J. Verweij, Lea K. Davis, Dirk J. Smit, James J. Crowley, Jeremiah M. Scharf, Murray B. Stein, Joel Gelernter, Carol A. Mathews, Eske M. Derks, Manuel Mattheisen
Published in: Nature Genetics, Issue 57, 2025, ISSN 1061-4036
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41588-025-02189-Z

Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single-cell resolution

Author(s): Nicolò Caporale; Davide Castaldi; Marco Tullio Rigoli; Cristina Cheroni; Alessia Valenti; Sarah Stucchi; Manuel Lessi; Davide Bulgheresi; Sebastiano Trattaro; Martina Pezzali; Alessandro Vitriolo; Alejandro Lopez-Tobon; Matteo Bonfanti; Dario Ricca; Katharina T. Schmid; Matthias Heinig; Fabian J. Theis; Carlo Emanuele Villa; Giuseppe Testa
Published in: Nature Methods, 2024, ISSN 1548-7105
Publisher: Nature Publishing Group
DOI: 10.1038/S41592-024-02555-5

Decomposing the Brain in Autism: Linking Behavioral Domains to Neuroanatomical Variation and Genomic Underpinnings

Author(s): Hanna Seelemeyer, Caroline Gurr, Johanna Leyhausen, Lisa M. Berg, Charlotte M. Pretzsch, Tim Schäfer, Bassem Hermila, Christine M. Freitag, Eva Loth, Bethany Oakley, Luke Mason, Jan K. Buitelaar, Christian F. Beckmann, Dorothea L. Floris, et al
Published in: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2024, ISSN 2451-9030
Publisher: Elsevier
DOI: 10.1016/J.BPSC.2024.12.003

Parsing Autism Heterogeneity: Transcriptomic Subgrouping of Imaging-Derived Phenotypes in Autism

Author(s): Johanna Leyhausen, Caroline Gurr, Lisa M. Berg, Hanna Seelemeyer, Bassem Hermila, Tim Schäfer, Andreas G. Chiocchetti, Charlotte M. Pretzsch, Eva Loth, Bethany Oakley, Jan K. Buitelaar, Christian F. Beckmann, Tony Charman, Thomas Bourgeron, Eli Barthome, Tobias Banaschewski, Emily JH. Jones, Jumana Ahmad, Sara Ambrosino, Bonnie Auyeung, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian F. Beckmann, Sven Bölte, Thomas Bourgeron, Carsten Bours, Michael Brammer, Daniel Brandeis, Claudia Brogna, Yvette de Bruijn, Jan K. Buitelaar, Bhismadev Chakrabarti, Tony Charman, Ineke Cornelissen, Daisy Crawley, Flavio Dell’Acqua, Guillaume Dumas, Sarah Durston, Christine Ecker, Jessica Faulkner, Vincent Frouin, Pilar Garcés, David Goyard, Lindsay Ham, Hannah Hayward, Joerg Hipp, Rosemary Holt, Mark H. Johnson, Emily J.H. Jones, Prantik Kundu, Meng-Chuan Lai, Xavier Liogier D’ardhuy, Michael V. Lombardo, Eva Loth, David J. Lythgoe, René Mandl, Andre Marquand, Luke Mason, Maarten Mennes, Andreas Meyer-Lindenberg, Carolin Moessnang, Nico Bast, Declan G.M. Murphy, Bethany Oakley, Laurence O’Dwyer, Marianne Oldehinkel, Bob Oranje, Gahan Pandina, Antonio M. Persico, Barbara Ruggeri, Amber Ruigrok, Jessica Sabet, Roberto Sacco, Antonia San José Cáceres, Emily Simonoff, Will Spooren, Julian Tillmann, Roberto Toro, Heike Tost, Jack Waldman, Steve C.R. Williams, Caroline Wooldridge, Marcel P. Zwiers, Declan Murphy, Christine Ecker
Published in: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2025, ISSN 2451-9022
Publisher: Elsevier BV
DOI: 10.1016/J.BPSC.2025.07.001

Mid-childhood autism sibling recurrence in infants with a family history of autism

Author(s): Tessel Bazelmans, Rowan Arthur, Greg Pasco, Elizabeth Shephard, Bosiljka Milosavljevic, Jannath Begum Ali, Andrew Pickles, Mark H. Johnson, Emily J. H. Jones, Tony Charman
Published in: Autism Research, 2024, ISSN 1939-3806
Publisher: Wiley
DOI: 10.1002/AUR.3182

Differences in Intrinsic Gray Matter Connectivity and Their Genomic Underpinnings in Autism Spectrum Disorder

Author(s): Leyhausen J, Schäfer T, Gurr C, Berg LM, Seelemeyer H, Pretzsch CM, Loth E, Oakley B, Buitelaar JK, Beckmann CF, Floris DL, Charman T, Bourgeron T, Banaschewski T, Jones EJH, Tillmann J, Chatham C; EU-AIMS LEAP Group; Murphy DG, Ecker C.
Published in: Biol Psychiatry, 2023, ISSN 0006-3223
Publisher: The Society of Biological Psychiatry
DOI: 10.1016/J.BIOPSYCH.2023.06.010

Book chapters (1)

Neurodiverse Research Collaboration Within a European Biomedical Project: Limits and Possibilities

Author(s): Joke Struyf, Cecilia Ingard & Hanna Bertilsdotter Rosqvist
Published in: The Palgrave Handbook of Research Methods and Ethics in Neurodiversity Studies, 2024
Publisher: Palgrave Macmillan, Cham
DOI: 10.1007/978-3-031-66127-3_5