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CORDIS

Improve Safety in Polymedication by Managing Drug-Drug-Gene Interactions

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Publications

European Journal of Human Genetics (opens in new window)

Author(s): Hanna Maria Kariis; Dage Särg; Kristi Krebs; Maarja Jõeloo; Kadri Kõiv; Kairit Sirts; Georgi Hudjashov; Dage Särg; Maris Alver; Kelli Lehto; Lili Milani
Published in: European Journal of Human Genetics, Issue 33, 2025, ISSN 1018-4813
Publisher: nature
DOI: 10.1038/S41431-025-01894-X

CPT: Pharmacometrics and Systems Pharmacology (opens in new window)

Author(s): Helena Leonie Hanae Loer; Christina Kovar; Simeon Rüdesheim; Fatima Zahra Marok; Laura Maria Fuhr; Dominik Selzer; Matthias Schwab; Thorsten Lehr
Published in: CPT: Pharmacometrics & Systems Pharmacology, Issue 13, 2024, ISSN 2163-8306
Publisher: Nature Publishing Group
DOI: 10.22028/D291-42669

CPT: Pharmacometrics and Systems Pharmacology (opens in new window)

Author(s): Christina Kovar; Helena Leonie Hanae Loer; Simeon Rüdesheim; Laura Maria Fuhr; Fatima Zahra Marok; Dominik Selzer; Matthias Schwab; Thorsten Lehr
Published in: CPT: Pharmacometrics & Systems Pharmacology, Issue 13, 2024, ISSN 2163-8306
Publisher: Nature Publishing Group
DOI: 10.22028/D291-42685

Model‐Based Prediction of Clinically Relevant Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation (opens in new window)

Author(s): Katharina M. Götz, Amin T. Turki, Katharina Och, Dominik Selzer, Christian Brossette, Norbert Graf, Jochen Rauch, Stefan Theobald, Yvonne Braun, Kerstin Rohm, Gabriele Weiler, Simeon Rüdesheim, Matthias Schwab, Lisa Eisenberg, Nico Pfeifer, Stephan Kiefer, Ulf Schwarz, Claudia Riede, Sigrun Smola, Dietrich W. Beelen, Dominic Kaddu‐Mulindwa, Jürgen Rissland, Jörg Bittenbring, Thorsten Lehr
Published in: Clinical Pharmacology & Therapeutics, Issue 117, 2025, ISSN 0009-9236
Publisher: Wiley
DOI: 10.1002/CPT.3580

A Comprehensive <scp>CYP2D6</scp> Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development (opens in new window)

Author(s): Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Dominik Selzer, Donato Teutonico, Annika R. P. Schneider, Juri Solodenko, Sebastian Frechen, Maaike van der Lee, Dirk Jan A. R. Moes, Jesse J. Swen, Matthias Schwab, Thorsten Lehr
Published in: Clinical Pharmacology &amp; Therapeutics, Issue 117, 2025, ISSN 0009-9236
Publisher: Wiley
DOI: 10.1002/CPT.3604

Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset (opens in new window)

Author(s): Jakob Sommer; Justyna Wozniak; Judith Schmitt; Jana Koch; Julia C. Stingl; Katja S. Just
Published in: Biomedicines, Issue 12, 2024, ISSN 2227-9059
Publisher: MDPI
DOI: 10.18154/RWTH-CONV-253072

Pharmacogenetic Panel Testing: A Review of Current Practice and Potential for Clinical Implementation (opens in new window)

Author(s): R. Mosch, M. van der Lee, H.J. Guchelaar, J.J. Swen
Published in: Annual Review of Pharmacology and Toxicology, Issue 65, 2025, ISSN 0362-1642
Publisher: Annual Reviews
DOI: 10.1146/ANNUREV-PHARMTOX-061724-080935

Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases (opens in new window)

Author(s): Tuomo Kiiskinen, Pyry Helkkula, Kristi Krebs, Juha Karjalainen, Elmo Saarentaus, Nina Mars, Arto Lehisto, Wei Zhou, Mattia Cordioli, Sakari Jukarainen, Joel T. Rämö, Juha Mehtonen, Kumar Veerapen, Markus Räsänen, Sanni Ruotsalainen, Mutaamba Maasha, F
Published in: Nature Medicine, Issue 29, 2023, ISSN 1078-8956
Publisher: Nature Medicine (Nat Med)
DOI: 10.1038/s41591-022-02122-5

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