Project description DEENESFRITPL Towards a more sustainable European pharmaceutical production of APIs Pharmaceuticals comprise a wide variety of chemical compounds designed to guarantee safe and effective therapies. The active pharmaceutical ingredients (APIs) are those that deliver the beneficial health effects experienced by patients. The goal of the EU-funded TransPharm project is to develop more sustainable and greener APIs that simultaneously reduce the environmental footprint and the dependence on third countries for API production. TransPharm will deliver digital tools and guidelines based on artificial intelligence for the development of greener pharmaceutical products and APIs, as well as models to judge their impact. The result will be a more independent and competitive European pharmaceutical industry, which can ensure the timely delivery of sustainable and green therapeutics to its citizens. Show the project objective Hide the project objective Objective TransPharm two-track approach focusses on the one hand on the compounds itself by identifying greener and more sustainable-by-design Active Pharmaceutical Ingredients (APIs) and on the other hand reducing the environmental impact and resilience of the manufacturing process by optimizing the synthesis route of new APIs in continuous flow and by proposing greener alternative solvents.The aim of the project is to (i) analyse and predict flow behaviour and environmental biodegradability of APIs and their synthesis pathways; (ii) identify greener and more sustainable alternatives to pharmaceutical products / APIs of concern; (iii) reduce the footprint and create important shortcuts in synthetic schemes of APIs; and (iv) assess the sustainability of pharmaceuticals over their entire life cycle. To reach the envisaged aims, the project will deliver four toolboxes (consisting of digital tools and guidelines) for the development of greener pharmaceutical products and APIs. These toolboxes will be used to (v) assess the potential to move towards the transition to greener, more agile pharmaceutical production. In addition, TransPharm will elaborate on the business case for sustainable pharmaceutical products or APIs and what is needed to bring them to the market. The project will also make sure that (vi) key project results and knowledge are properly transferred towards targeted stakeholders.TransPharm?s outcome contribute to a Europe, that is self-sufficient by reducing dependence on API production in third countries; making the EU healthcare industry more competitive, sustainable and reliable, ensuring timely supply of essential medicines from particularly complex or critical supply and distribution chains and positioning EU as a leader in innovative technologies. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugssocial scienceseconomics and businessbusiness and managementbusiness modelssocial scienceseconomics and businesseconomicsproduction economicsproductivitysocial scienceseconomics and businesseconomicssustainable economy Keywords Active Pharmaceutical Ingredient Benign-by-Design Biodegradability Flow-chemistry Artificial Intelligence Predictive tool Integrated sustainability assessment Programme(s) HORIZON.2.1 - Health Main Programme HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine Topic(s) HORIZON-HLTH-2021-IND-07-01 - Green pharmaceuticals Call for proposal HORIZON-HLTH-2021-IND-07 See other projects for this call Funding Scheme HORIZON-RIA - HORIZON Research and Innovation Actions Coordinator UNIVERSITEIT GENT Net EU contribution € 2 037 908,75 Address Sint pietersnieuwstraat 25 9000 Gent Belgium See on map Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (10) Sort alphabetically Sort by Net EU contribution Expand all Collapse all HELSINGIN YLIOPISTO Finland Net EU contribution € 1 254 345,00 Address Yliopistonkatu 3 00014 Helsingin yliopisto See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CIRCA GROUP AS Norway Net EU contribution € 385 052,00 Address Sjolyst plass 2 0278 Oslo See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Norge Oslo og Viken Oslo Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,50 STICHTING RADBOUD UNIVERSITEIT Netherlands Net EU contribution € 971 487,00 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,50 LEUPHANA UNIVERSITAT LUNEBURG Germany Net EU contribution € 778 895,00 Address Scharnhorststrasse 1 21335 Luneburg See on map Region Niedersachsen Lüneburg Lüneburg, Landkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 KELADA PHARMACHEM LIMITED Ireland Net EU contribution € 1 218 778,75 Address 161 rathmines road lower A94 Dublin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ORION OYJ Finland Net EU contribution € 0,00 Address Orionintie 1 02200 Espoo See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 37 500,00 RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Netherlands Net EU contribution € 557 185,00 Address Antonie van leeuwenhoeklaan 9 3721 MA Bilthoven See on map Region West-Nederland Utrecht Utrecht Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ECOLOGIC INSTITUT gemeinnützige GmbH Germany Net EU contribution € 216 532,50 Address Pfalzburger strasse 43-44 10717 Berlin See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Berlin Berlin Berlin Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BENKEI France Net EU contribution € 194 356,25 Address Zac bir hakeim/gambetta 97 cours gambetta et 1 avenue jules jusserand 69003 Lyon See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LATVIJAS ORGANISKAS SINTEZES INSTITUTS Latvia Net EU contribution € 425 060,00 Address Aizkraukles 21 LV-1006 Riga See on map Region Latvija Latvija Rīga Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSITY OF YORK United Kingdom Net EU contribution € 0,00 Address Heslington YO10 5DD York north yorkshire See on map Region Yorkshire and the Humber North Yorkshire York Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data
