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Next generation toolbox for greener pharmaceuticals design & manufacturing towards reduced environmental impact

Objective

Pharmaceuticals have undoubtably made our world a better place, ensuring longer and healthier lives. However, pharmaceuticals and their active metabolites are rapidly emerging environmental toxicants. It is thus critical that we fully understand, and mitigate where nec-essary, the environmental impact resulting from their production, use and disposal. In this direction, ENVIROMED addresses two aspects of the environmental impact of pharmaceuticals, a) impact of the processes in manufacturing the compound, and b) impact of the compound itself, during its lifecycle. The project narrows the knowledge gap when it comes to the effect of pharmaceutical compounds, and their derivatives, in the environment as it enables the better understanding the environmental impact of such compounds, throughout their lifecycle. It aims to offer (via extensive monitoring campaigns & scientific studies) information regarding occurrence of pharmaceuticals in the environment, their persistence, environmental fate, and toxicity (via in-vitro & in-vivo models) as well as application of in-silico methods to provide information about the basic risk management and fate prediction in the environment. Brief ideas about toxicity endpoints, available ecotoxicity databases, and expert systems employed for rapid toxicity predictions of ecotoxicity of pharmaceuticals will also be taken into account, in order to have a comprehensive approach to pharmaceuticals' Lifecycle Assessment (LCA). Moreover, the project aims at developing a set of technologies that enable greener and overall, more efficient pharmaceuticals production, which include: a) Green-by-design in-silico drug development; b) Novel sensing to allow reduction of rinsing chemicals and cycles; c) a robust Continuous Biomanufacturing line (CBM), which makes use of AI-enabled process optimisation and prediction, using data assimilation based on chemical sensing and energy disaggregation/monitoring. Training activities and a robust exploitation

Coordinator

RISA SICHERHEITSANALYSEN GMBH
Net EU contribution
€ 902 500,00
Address
Xantener Strasse 11
10707 Berlin
Germany

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Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00

Participants (14)

PFIZER IRELAND PHARMACEUTICALS
Ireland
Net EU contribution
€ 382 500,00
Address
Ringaskiddy Operations Support Group
T12 Cork

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Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CLOUDPHARM PRIVATE COMPANY
Greece
Net EU contribution
€ 533 375,00
Address
Leoforos Kifissias 44
15125 Maroussi

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Βόρειος Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
NOVO NORDISK A/S
Denmark
Net EU contribution
€ 424 250,00
Address
Novo Alle 1
2880 Bagsvaerd

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Region
Danmark Hovedstaden Københavns omegn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
TECHNISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 1 155 937,00
Address
Karlsplatz 13
1040 Wien

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,50
PLEGMA LABS TECHNOLOGIKES LYSEIS ANONYMOS ETAIRIA
Greece
Net EU contribution
€ 271 250,00
Address
Fragkoklisias 7
151 25 Marousi

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Βόρειος Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,06
UNIVERSITAET ULM
Germany
Net EU contribution
€ 675 000,00
Address
Helmholtzstrasse 16
89081 Ulm

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Region
Baden-Württemberg Tübingen Ulm, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
MITERA IDIOTIKI GENIKI, MAIEYTIKI,GYNAIKOLOGIKI KAI PAIDIATRIKI KLINIKI ANONYMI ETAIREIA
Greece
Net EU contribution
€ 408 125,00
Address
Odos Leof Kifisias And Er Stavrou 6
151 23 Marousi Athina

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Region
Βόρειος Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UAB METIS BALTIC
Lithuania
Net EU contribution
€ 288 125,00
Address
Jogailos G 4
01116 Vilnius

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Lietuva Sostinės regionas Vilniaus apskritis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD
Cyprus
Net EU contribution
€ 365 000,00
Address
Agias Elenis 6 Agias Elenis Building 4th Floor Flat Office 43
1060 Lefkosia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Κύπρος Κύπρος Κύπρος
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ETAIREIA YDREYSEOS KAI APOCHETEFSEOS PROTEYOYSIS ANONIMI ETAIREIA
Greece
Net EU contribution
€ 312 375,00
Address
Oropou - Galatsi 156
11146 Athina

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 552 625,00
Address
Piazzale Aldo Moro 7
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
INNOVATION IN RESEARCH & ENGINEERING SOLUTIONS
Belgium
Net EU contribution
€ 378 750,00
Address
Rue Koningin Astridlaan 59b/9
1780 Wemmel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Halle-Vilvoorde
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
RESEARCH CENTER FOR NON DESTRUCTIVE TESTING GMBH
Austria
Net EU contribution
€ 488 250,00
Address
Altenberger Strasse 69 Science Park 2/2 Og
4040 Linz

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Region
Westösterreich Oberösterreich Linz-Wels
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ETHNICON METSOVION POLYTECHNION
Greece
Net EU contribution
€ 380 000,00
Address
Heroon Polytechniou 9 Zographou Campus
157 80 Athina

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00