Project description DEENESFRITPL Turning medicines green to reduce pollution The medicines that save us could end up harming us if not disposed of properly. Unfortunately, the concentration of pharmaceuticals in waterways is reaching dangerous levels. In this context, the EU-funded ENVIROMED project will narrow the knowledge gap when it comes to the effect of pharmaceutical compounds, and their derivatives, on the environment. ENVIROMED will shed light on the environmental impact of such compounds, throughout their lifecycle. The findings will provide information about the occurrence of pharmaceuticals in the environment, their persistence and environmental fate. The project will also aim to develop a set of technologies that enable greener and overall, more efficient pharmaceutical production. Show the project objective Hide the project objective Objective Pharmaceuticals have undoubtably made our world a better place, ensuring longer and healthier lives. However, pharmaceuticals and their active metabolites are rapidly emerging environmental toxicants. It is thus critical that we fully understand, and mitigate where nec-essary, the environmental impact resulting from their production, use and disposal. In this direction, ENVIROMED addresses two aspects of the environmental impact of pharmaceuticals, a) impact of the processes in manufacturing the compound, and b) impact of the compound itself, during its lifecycle. The project narrows the knowledge gap when it comes to the effect of pharmaceutical compounds, and their derivatives, in the environment as it enables the better understanding the environmental impact of such compounds, throughout their lifecycle. It aims to offer (via extensive monitoring campaigns & scientific studies) information regarding occurrence of pharmaceuticals in the environment, their persistence, environmental fate, and toxicity (via in-vitro & in-vivo models) as well as application of in-silico methods to provide information about the basic risk management and fate prediction in the environment. Brief ideas about toxicity endpoints, available ecotoxicity databases, and expert systems employed for rapid toxicity predictions of ecotoxicity of pharmaceuticals will also be taken into account, in order to have a comprehensive approach to pharmaceuticals' Lifecycle Assessment (LCA). Moreover, the project aims at developing a set of technologies that enable greener and overall, more efficient pharmaceuticals production, which include: a) Green-by-design in-silico drug development; b) Novel sensing to allow reduction of rinsing chemicals and cycles; c) a robust Continuous Biomanufacturing line (CBM), which makes use of AI-enabled process optimisation and prediction, using data assimilation based on chemical sensing and energy disaggregation/monitoring. Training activities and a robust exploitation Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencescomputer and information sciencesdatabasesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencescomputer and information sciencesartificial intelligenceexpert systemssocial sciencessociologygovernancecrisis management Keywords laser-based sensors Green-by-design compounds ecotoxicity studies artificial intelligence life cycle analysis Programme(s) HORIZON.2.1 - Health Main Programme HORIZON.2.1.5 - Tools, Technologies and Digital Solutions for Health and Care, including personalised medicine Topic(s) HORIZON-HLTH-2021-IND-07-01 - Green pharmaceuticals Call for proposal HORIZON-HLTH-2021-IND-07 See other projects for this call Funding Scheme RIA - Research and Innovation action Coordinator RISA SICHERHEITSANALYSEN GMBH Net EU contribution € 902 500,00 Address Xantener strasse 11 10707 Berlin Germany See on map Region Berlin Berlin Berlin Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (14) Sort alphabetically Sort by Net EU contribution Expand all Collapse all PFIZER IRELAND PHARMACEUTICALS Ireland Net EU contribution € 382 500,00 Address Ringaskiddy operations support group T12 Cork See on map Region Ireland Eastern and Midland Dublin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CLOUDPHARM PRIVATE COMPANY Greece Net EU contribution € 533 375,00 Address Leoforos kifissias 44 15125 Maroussi See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NOVO NORDISK A/S Denmark Net EU contribution € 424 250,00 Address Novo alle 1 2880 Bagsvaerd See on map Region Danmark Hovedstaden Københavns omegn Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TECHNISCHE UNIVERSITAET WIEN Austria Net EU contribution € 1 155 937,00 Address Karlsplatz 13 1040 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,50 PLEGMA LABS TECHNOLOGIKES LYSEIS ANONYMOS ETAIRIA Greece Net EU contribution € 271 250,00 Address Neratziotissis 115 151 24 Marousi See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,06 UNIVERSITAET ULM Germany Net EU contribution € 675 000,00 Address Helmholtzstrasse 16 89081 Ulm See on map Region Baden-Württemberg Tübingen Ulm, Stadtkreis Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MITERA IDIOTIKI GENIKI, MAIEYTIKI,GYNAIKOLOGIKI KAI PAIDIATRIKI KLINIKI ANONYMI ETAIREIA Greece Net EU contribution € 408 125,00 Address Odos leof kifisias and er stavrou 6 151 23 Marousi athina See on map Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UAB METIS BALTIC Lithuania Net EU contribution € 288 125,00 Address Jogailos g 4 01116 Vilnius See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Lietuva Sostinės regionas Vilniaus apskritis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD Cyprus Net EU contribution € 365 000,00 Address Agias elenis 6 agias elenis building 4th floor flat office 43 1060 Lefkosia See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Κύπρος Κύπρος Κύπρος Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ETAIREIA YDREYSEOS KAI APOCHETEFSEOS PROTEYOYSIS ANONIMI ETAIREIA Greece Net EU contribution € 312 375,00 Address Oropou - galatsi 156 11146 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CONSIGLIO NAZIONALE DELLE RICERCHE Italy Net EU contribution € 552 625,00 Address Piazzale aldo moro 7 00185 Roma See on map Region Centro (IT) Lazio Roma Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INNOVATION IN RESEARCH & ENGINEERING SOLUTIONS Belgium Net EU contribution € 378 750,00 Address Rue koningin astridlaan 59b/9 1780 Wemmel See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Halle-Vilvoorde Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 RESEARCH CENTER FOR NON DESTRUCTIVE TESTING GMBH Austria Net EU contribution € 488 250,00 Address Altenberger strasse 69 science park 2/2 og 4040 Linz See on map Region Westösterreich Oberösterreich Linz-Wels Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ETHNICON METSOVION POLYTECHNION Greece Net EU contribution € 380 000,00 Address Heroon polytechniou 9 zographou campus 157 80 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all ALPES LASERS SA Switzerland Net EU contribution € 0,00 Address Avenue des paquiers 1 2072 Saint-blaise See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 AGILENT TECHNOLOGIES LDA UK LIMITED United Kingdom Net EU contribution € 0,00 Address 5500 lakeside cheadle royal business park SK8 3GR Cheadle See on map Region North West (England) Greater Manchester Greater Manchester South East Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00