Centre of Excellence for the Technologies of Gene and Cell Therapy

Project Information

CTGCT

Grant agreement ID: 101059842

DOI

10.3030/101059842

EC signature date 25 April 2023

Start date 1 September 2023

End date 31 August 2029

Funded under

• Widening participation and spreading excellence

Total cost

€ 14 067 762,50

EU contribution

€ 14 067 762,50

Coordinated by

KEMIJSKI INSTITUT
Slovenia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (3)

List of CTGCT’s products and services

Detailed list of products and services offered by CTGCT

Plan for dissemination and exploitation including communication activities

Thorough communication and dissemination plan in order to gain the visibility of the CTGCT

Advanced therapies learning box launch

Report on learning material about the advanced therapies, to be used in communication and dissemination activities, published

Publications

Peer reviewed articles (12)

CTGCT, Centre of Excellence for the Technologies of Gene and Cell Therapy: Collaborative translation of scientific discoveries into advanced treatments for neurological rare genetic diseases and cancer

Author(s): Darja Marolt Presen; Duško Lainšček; Jane Kinghorn; Zsolt Sebestyen; Jurgen Kuball; Leila Amini; Petra Reinke; Anke Fuchs; Roman Jerala; Mojca Benčina
Published in: Computational and Structural Biotechnology Journal, Issue 27, 2025, ISSN 2001-0370
Publisher: Elsevier
DOI: 10.1016/J.CSBJ.2024.11.051

Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors

Author(s): Sara Orehek, Taja Železnik Ramuta, Duško Lainšček, Špela Malenšek, Martin Šala, Mojca Benčina, Roman Jerala, Iva Hafner-Bratkovič
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-55083-3

Coupling of Spectrin Repeat Modules for the Assembly of Nanorods and Presentation of Protein Domains

Author(s): Klemen Mezgec, Jaka Snoj, Liza Ulčakar, Ajasja Ljubetič, Magda Tušek Žnidarič, Miha Škarabot, Roman Jerala
Published in: ACS Nano, Issue 18, 2024, ISSN 1936-0851
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.4C07701

The art of designed coiled-coils for the regulation of mammalian cells

Author(s): Tjaša Plaper, Erik Rihtar, Taja Železnik Ramuta, Vida Forstnerič, Vid Jazbec, Filip Ivanovski, Mojca Benčina, Roman Jerala
Published in: Cell Chemical Biology, Issue 31, 2024, ISSN 2451-9456
Publisher: Elsevier BV
DOI: 10.1016/J.CHEMBIOL.2024.06.001

Ultrasound-mediated spatial and temporal control of engineered cells in vivo

Author(s): Filip Ivanovski, Maja Meško, Tina Lebar, Marko Rupnik, Duško Lainšček, Miha Gradišek, Roman Jerala, Mojca Benčina
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-51620-2

Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

Author(s): Erik Rihtar, Tina Fink, Tina Lebar, Duško Lainšček, Živa Kolenc, Lucija Kadunc Polajnar, Roman Jerala
Published in: Cell Chemical Biology, Issue 32(3), 2025, ISSN 2451-9448
Publisher: Elsevier Ltd.
DOI: 10.1016/J.CHEMBIOL.2025.01.007

Protein Gas Vesicles of <i>Bacillus megaterium</i> as Enhancers of Ultrasound-Induced Transcriptional Regulation

Author(s): Vid Jazbec, Nina Varda, Ernest Šprager, Maja Meško, Sara Vidmar, Rok Romih, Marjetka Podobnik, Andreja Kežar, Roman Jerala, Mojca Benčina
Published in: ACS Nano, Issue 18, 2024, ISSN 1936-0851
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSNANO.4C01498

Ultrasound-responsive mammalian cell synthetic biology

Author(s): Filip Ivanovski; Vid Jazbec; Nina Varda; Roman Jerala; Mojca Benèina
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2025, ISSN 1525-8955
Publisher: IEEE
DOI: 10.1109/TUFFC.2025.3570813

Paving the way toward treatment solutions for CTNNB1 syndrome: a patient organization perspective

Author(s): Špela Miroševič, Shivang Khandelwal, Emily Amerson, Effie Parks, Mariana Parks, Lauren Cochran, Ana González Hernández, Mirela Ferraro, Leszek Lisowski, Andrea Perez-Iturralde, Wendy Chung, Michele H. Jacob, Nina Žakelj, Duško Lainšček, Vida Forstnerič, P
Published in: Therapeutic Advances in Rare Disease, Issue 6, 2025, ISSN 2633-0040
Publisher: SAGE
DOI: 10.1177/26330040251318355

MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis

Author(s): Duško Lainšček, Simon Horvat, Klemen Dolinar, Filip Ivanovski, Rok Romih, Sergej Pirkmajer, Roman Jerala, Mateja Manček-Keber
Published in: Cell Communication and Signaling, Issue 22, 2024, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1186/S12964-024-01930-1

Mucoadhesive film for oral delivery of vaccines for protection of the respiratory tract

Author(s): Hana Esih, Klemen Mezgec, Martina Billmeier, Špela Malenšek, Mojca Benčina, Blaž Grilc, Sara Vidmar, Mirjana Gašperlin, Marjan Bele, Mihaela Zidarn, Tatjana Lejko Zupanc, Tina Morgan, Ingo Jordan, Volker Sandig, Silke Schrödel, Christian Thirion,
Published in: Journal of controlled release, Issue 371, 2024, ISSN 0168-3659
Publisher: Elsevier B.V.
DOI: 10.1016/J.JCONREL.2024.05.041

Designed allosteric protein logic

Author(s): Tjaša Plaper, Estera Merljak, Tina Fink, Tadej Satler, Ajasja Ljubetič, Duško Lainšček, Vid Jazbec, Mojca Benčina, Sintija Stevanoska, Sašo Džeroski, Roman Jerala
Published in: Cell Discovery, Issue 10, 2024, ISSN 2056-5968
Publisher: Springer Nature
DOI: 10.1038/S41421-023-00635-Y

Intellectual Property Rights

Trademark (3)

CTGCT

Application/Publication number: 202370936 1
Date: 2023-10-30
Applicant(s): KEMIJSKI INSTITUT

CTGCT CENTRE FOR THE TECHNOLOGIES OF GENE AND CELL THERAPY

Application/Publication number: 202370937 1
Date: 2023-10-30
Applicant(s): KEMIJSKI INSTITUT

CTGCT

Application/Publication number: 202370935 1
Date: 2023-10-30
Applicant(s): KEMIJSKI INSTITUT