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Improved control of priority animal diseases: Novel vaccines and companion diagnostic tests for African horse sickness, peste des petits ruminants and foot-and-mouth disease

Project description

Novel vaccines for priority farm animal diseases

Currently available vaccines for African horse sickness (AHS), peste des petits ruminants (PPR) and foot-and-mouth disease (FMD) demonstrate shortcomings, leaving the EU vulnerable to these transboundary farm animal diseases. The EU-funded SPIDVAC project is bringing together 13 international industry partners for the development of veterinary vaccines and diagnostic tools. The goal is to develop novel vaccines against AHS, PPR and FMD and, after evaluation in vitro, demonstrate their safety and efficacy in small-animal models and the target species. In addition, the consortium will develop a companion diagnostic test to identify infected and vaccinated animals. The project will increase understanding of infection mechanisms and evaluate the acceptability of vaccines for stakeholders in endemic areas.

Objective

Current vaccines for African horse sickness (AHS), peste des petits ruminants (PPR) and foot-and-mouth disease (FMD) have critical shortcomings that leave the European Union vulnerable to these category A transboundary animal diseases, but control strategies that rely on culling alone are increasingly rejected by the public. At the same time, the risk of an introduction of AHS, PPR or FMD into Europe is growing, driven by climate change, global trade and long-distance travel. Innovative vaccines and companion diagnostics that are grounded in an increased knowledge of pathogenesis and immunity are urgently required to improve the capacity to prevent introductions and contain outbreaks, which are a major threat to European agriculture. The SPIDVAC (Safe Priority Infectious Diseases VACcines) consortium consists of 13 partners from Germany, France, Spain, the United Kingdom, the Netherlands, South Africa and Senegal, who will develop innovative vaccines against AHS, PPR and FMD and evaluate their capabilities in vitro, demonstrate the safety and efficacy of the candidate vaccines in small-animal models and in the target species and develop companion diagnostic to reliably differentiate between infected and vaccinated animals (DIVA). In addition, the project will increase knowledge on the mechanisms of infection, virulence and immunity and study the acceptability of vaccines for stakeholders in endemic areas. The consortium includes industry partners for veterinary vaccines and diagnostic tools, who will ensure the technological readiness and market relevance of the newly developed tools, which will help policy makers, veterinary services and business operators reduce the burden of infectious animal diseases, contribute to a sustainable livestock industry and promote public and animal health from farm to fork.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-IA - HORIZON Innovation Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-CL6-2021-FARM2FORK-01

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Coordinator

FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 388 037,50
Address
SUDUFER 10
17493 Greifswald-Insel Riems
Germany

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Region
Mecklenburg-Vorpommern Mecklenburg-Vorpommern Vorpommern-Greifswald
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 388 037,50

Participants (9)

Partners (3)

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