Project description DEENESFRITPL Introducing the new era of gene therapy Gene therapy holds great promise for revolutionising modern medicine. It represents a paradigm shift in approaching disease treatment, as it address the root causes of diseases instead of focusing on treating their symptoms. With unparalleled potential for both cure and economic impact, this groundbreaking medical biotechnology demands cutting-edge research and innovation to address the thousands of severe human diseases. With this in mind, the EU-funded GeneT project will establish a unique gene therapy research and innovation hub in the Centro region of Portugal. Anchored at the University of Coimbra, GeneT unites scientific excellence with international cooperation to pioneer new gene therapy solutions capable of alleviating suffering and fostering economic growth. Show the project objective Hide the project objective Objective The main goal of the present project is the creation of a Gene Therapy research & innovation hub rooted in a Center of Excellence (CoE) located in the CENTRO (center) region of Portugal – the GeneT. This CoE will capitalize on the already existing RD&I capacity in the field at the University of Coimbra (UC) – the regional (and national) pivot of the innovation potential and knowledge transfer in Red Biotechnology – and act as an (inter)national enabler of scientific and business excellence in Gene Therapy innovation and manufacturing.Gene Therapy is the latest revolution in the treatment of severe human diseases with the highest curative and economic potential in the health sector. Extraordinary results have already been achieved in the treatment of a few neurological, ophthalmic, hepatic, oncological and hematological disorders with outstanding clinical and economic impacts. UC, notably its Center for Neuroscience and Cell Biology, has proven scientific excellence in specific areas of the field, and a matchless ecosystem to strive in this high added-value sector, which encompasses the Coimbra University Hospitals and the Biotechnology Park BIOCANT, recognized as the epicenter of the biotech industry in Portugal.To achieve its goal, the project will team-up with the University of Sheffield, home of the Gene Therapy Innovation and Manufacturing Centre, a UK pioneer hub dedicated to advancing the clinical development of new genetic treatments, and the University of Eastern Finland, which hosts the Finish National Virus Vector Laboratory with viral vector GMP production capacity and scale-up (key to gene therapy development). These two top European institutions are international references in the field at fundamental, translational and innovation levels.GeneT will thus become a beacon of excellent in Gene Therapy R&I, with enormous impact in the decrease of mortality and suffering, while contributing to the economic recovery and growth of Portugal and the EU. Fields of science medical and health sciencesmedical biotechnologygenetic engineeringgene therapysocial scienceseconomics and businessbusiness and managementinnovation managementsocial sciencespolitical sciencespolitical transitionsnatural sciencesbiological sciencescell biology Keywords Gene Therapy Red Biotechnology Frontier research Manufacturing innovation Investigator-initiated Clinical Studies (IICS) Programme(s) HORIZON.4.1 - Widening participation and spreading excellence Main Programme HORIZON.4.1.1 - Teaming Topic(s) HORIZON-WIDERA-2022-ACCESS-01-01-two-stage - Teaming for Excellence Call for proposal HORIZON-WIDERA-2022-ACCESS-01-two-stage See other projects for this call Funding Scheme HORIZON-CSA - HORIZON Coordination and Support Actions Coordinator UNIVERSIDADE DE COIMBRA Net EU contribution € 13 102 152,50 Address PACO DAS ESCOLAS 3004-531 Coimbra Portugal See on map Region Continente Centro (PT) Região de Coimbra Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 13 102 152,50 Participants (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all ITA-SUOMEN YLIOPISTO Finland Net EU contribution € 901 552,50 Address YLIOPISTONRANTA 8 70211 KUOPIO See on map Region Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 901 552,50 Partners (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all THE UNIVERSITY OF SHEFFIELD United Kingdom Net EU contribution € 0,00 Address FIRTH COURT WESTERN BANK S10 2TN Sheffield See on map Region Yorkshire and the Humber South Yorkshire Sheffield Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA EPE Portugal Net EU contribution € 0,00 Address AV DE BISSAYA, PRACETA DE MOTA PINTO 3000-075 Coimbra See on map Region Continente Centro (PT) Região de Coimbra Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost No data
