Centre for Digitalisation of Biology Towards the Next-Generation of Biosustainable Products

Informations projet

DIGIBIO

N° de convention de subvention: 101060066

DOI

10.3030/101060066

Date de signature de la CE 26 Avril 2023

Date de début 1 Septembre 2023

Date de fin 31 Août 2029

Financé au titre de

• Widening participation and spreading excellence

Coût total

€ 14 942 500,00

Contribution de l’UE

€ 14 942 500,00

Coordonné par

TARTU ULIKOOL
Estonia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Publications

Peer reviewed articles (47)

Stomatal CO2 responses at sub- and above-ambient CO2 levels employ different pathways in Arabidopsis

Auteurs: Kaspar Koolmeister, Ebe Merilo, Hanna Hõrak, Hannes Kollist
Publié dans: Plant Physiology, Numéro 196, 2024, ISSN 0032-0889
Éditeur: Oxford University Press (OUP)
DOI: 10.1093/PLPHYS/KIAE320

Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness

Auteurs: Henri Ingelman, James K. Heffernan, Audrey Harris, Steven D. Brown, Kurshedaktar Majibullah Shaikh, Asfand Yar Saqib, Marina J. Pinheiro, Lorena Azevedo de Lima, Karen Rodriguez Martinez, Ricardo A. Gonzalez-Garcia, Grant Hawkins, Jim Daleiden, Loan Tran, Hunter Zeleznik, Rasmus O. Jensen, Vinicio Reynoso, Heidi Schindel, Jürgen Jänes, Séan D. Simpson, Michael Köpke, Esteban Marcellin, Kaspar Valgepea
Publié dans: New Biotechnology, Numéro 83, 2024, ISSN 1871-6784
Éditeur: Elsevier BV
DOI: 10.1016/J.NBT.2024.06.002

The PAZ domain of Aedes aegypti Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs.

Auteurs: Melinda Reuter, Rhys H. Parry, Melanie McDonald, Rommel J. Gestuveo, Rozeena Arif, Alexander A. Khromykh, Benjamin Brennan, Margus Varjak, Alfredo Castello, Lars Redecke, Esther Schnettler, Alain Kohl
Publié dans: RNA, 2025, ISSN 1355-8382
Éditeur: Cold Spring Harbor Laboratory
DOI: 10.1261/RNA.080149.124

Evaluation of enzyme-constrained genome-scale model through metabolic engineering of anaerobic co-production of 2,3-butanediol and glycerol by Saccharomyces cerevisiae

Auteurs: Gustav Sjöberg, Alīna Reķēna, Matilda Fornstad, Petri-Jaan Lahtvee, Antonius J.A. van Maris
Publié dans: Metabolic Engineering, Numéro 82, 2024, ISSN 1096-7176
Éditeur: Elsevier BV
DOI: 10.1016/J.YMBEN.2024.01.007

Exploring the resilience and stability of a defined human gut microbiota consortium: An isothermal microcalorimetric study

Auteurs: Anna Kattel, Valter Aro, Petri‐Jaan Lahtvee, Jekaterina Kazantseva, Arvi Jõers, Ranno Nahku, Isma Belouah
Publié dans: MicrobiologyOpen, Numéro 13, 2024, ISSN 2045-8827
Éditeur: Wiley
DOI: 10.1002/MBO3.1430

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

Auteurs: Sainan Wang, Suresh Mahalingam, Andres Merits
Publié dans: Reviews in Medical Virology, Numéro 35, 2025, ISSN 1052-9276
Éditeur: Wiley
DOI: 10.1002/RMV.70030

FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design

Auteurs: Wern Hann Ng, Xiang Liu, Zheng L. Ling, Camilla N. O. Santos, Lucas S. Magalhães, Andrew J. Kueh, Marco J. Herold, Adam Taylor, Joseph R. Freitas, Sandra Koit, Sainan Wang, Andrew R. Lloyd, Mauro M. Teixeira, Andres Merits, Roque P. Almeida, Nicholas J. C. King, Suresh Mahalingam
Publié dans: Nature Communications, Numéro 14, 2023, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-023-42330-2

LDLR is used as a cell entry receptor by multiple alphaviruses

Auteurs: Xiaofeng Zhai, Xiaoling Li, Michael Veit, Ningning Wang, Yu Wang, Andres Merits, Zhiwen Jiang, Yan Qin, Xiaoguang Zhang, Kaili Qi, Houqi Jiao, Wan-Ting He, Ye Chen, Yang Mao, Shuo Su
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-44872-5

Ultrasound effect on a biorefinery lignin-cellulose mixture

Auteurs: Kait Kaarel Puss, Peeter Paaver, Mart Loog, Siim Salmar
Publié dans: Ultrasonics Sonochemistry, Numéro 111, 2025, ISSN 1350-4177
Éditeur: Elsevier BV
DOI: 10.1016/J.ULTSONCH.2024.107071

Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria

Auteurs: Elisabetta Cacace, Manuela Tietgen, Meike Steinhauer, André Mateus, Tilman G. Schultze, Marina Eckermann, Marco Galardini, Vallo Varik, Alexandra Koumoutsi, Jordan J. Parzeller, Federico Corona, Askarbek Orakov, Michael Knopp, Amber Brauer-Nikonow, Peer Bork, Celia V. Romao, Michael Zimmermann, Peter Cloetens, Mikhail M. Savitski, Athanasios Typas, Stephan Göttig
Publié dans: Nature Communications, Numéro 16, 2025, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-58730-5

Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles

Auteurs: Wael Kamel, Vincenzo Ruscica, Azman Embarc-Buh, Zaydah R. de Laurent, Manuel Garcia-Moreno, Yana Demyanenko, Richard J. Orton, Marko Noerenberg, Meghana Madhusudhan, Louisa Iselin, Aino I. Järvelin, Maximilian Hannan, Eduardo Kitano, Samantha Moore, Andres Merits, Ilan Davis, Shabaz Mohammed, Alfredo Castello
Publié dans: Molecular Cell, Numéro 84, 2025, ISSN 1097-2765
Éditeur: Elsevier BV
DOI: 10.1016/J.MOLCEL.2024.11.015

Exploring Barmah Forest virus pathogenesis: molecular tools to investigate non-structural protein 3 nuclear localization and viral genomic determinants of replication

Auteurs: Ailar Omler, Margit Mutso, Mihkel Vaher, Joseph R. Freitas, Adam Taylor, Cassandra T. David, Gregory W. Moseley, Xiang Liu, Andres Merits, Suresh Mahalingam
Publié dans: mBio, Numéro 15, 2024, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/MBIO.00993-24

Phenotypic Variation and Relationships between Grain Yield, Protein Content and Unmanned Aerial Vehicle-Derived Normalized Difference Vegetation Index in Spring Wheat in Nordic–Baltic Environments

Auteurs: Zaiga Jansone, Zigmārs Rendenieks, Andris Lapāns, Ilmar Tamm, Anne Ingver, Andrii Gorash, Andrius Aleliūnas, Gintaras Brazauskas, Sahameh Shafiee, Tomasz Mróz, Morten Lillemo, Hannes Kollist, Māra Bleidere
Publié dans: Agronomy, Numéro 14, 2025, ISSN 2073-4395
Éditeur: MDPI AG
DOI: 10.3390/AGRONOMY14010051

Novel coronaviruses identified in livestock: The urgent need to enhance coronavirus surveillance to mitigate zoonotic risks

Auteurs: Kaili Qi, Jie Chen, Xing Ma, Dongyan Li, Guy Baele, Xinxin Li, Ying Qin, Xiang Ji, Mengmeng Zhu, Xin-xin Li, Dawei Guo, Andres Merits, Michael Veit, Xiaofeng Zhai, Jin Tian, Ningning Wang, Houqi Jiao
Publié dans: Journal of Infection, Numéro 91, 2025, ISSN 0163-4453
Éditeur: Elsevier BV
DOI: 10.1016/J.JINF.2025.106512

Novel universal vaccines to mitigate emerging avian influenza viruses

Auteurs: Yu Liu, Lifang Wang, Alexander Lai, Mei Kang, Yangrui Qi, Andres Merits, Xinyi Jiao, Xinyu Wang, Xiangrong Yu, Shuo Su, Zhiwen Jiang
Publié dans: Trends in Molecular Medicine, 2025, ISSN 1471-4914
Éditeur: Elsevier BV
DOI: 10.1016/J.MOLMED.2025.03.001

ALMT‐independent guard cell R‐type anion currents

Auteurs: Justyna Jaślan, Irene Marten, Liina Jakobson, Triinu Arjus, Rosalia Deeken, Cecilia Sarmiento, Alexis De Angeli, Mikael Brosché, Hannes Kollist, Rainer Hedrich
Publié dans: New Phytologist, Numéro 239, 2023, ISSN 0028-646X
Éditeur: Wiley
DOI: 10.1111/NPH.19124

Synthesis and import of GDP‐<scp>l</scp>‐fucose into the Golgi affect plant–water relations

Auteurs: Cezary Waszczak, Dmitry Yarmolinsky, Marina Leal Gavarrón, Triin Vahisalu, Maija Sierla, Olena Zamora, Ross Carter, Tuomas Puukko, Nina Sipari, Airi Lamminmäki, Jörg Durner, Dieter Ernst, J. Barbro Winkler, Lars Paulin, Petri Auvinen, Andrew J. Fleming, Mats X. Andersson, Hannes Kollist, Jaakko Kangasjärvi
Publié dans: New Phytologist, Numéro 241, 2025, ISSN 0028-646X
Éditeur: Wiley
DOI: 10.1111/NPH.19378

The catalytic tetrad of Aedes aegypti argonaute 2 is critical for the antiviral activity of the exogenous siRNA pathway

Auteurs: Krittika Dummunee, Rhys H. Parry, Lars Redecke, Margus Varjak, Benjamin Brennan, Alain Kohl, Melanie McFarlane
Publié dans: Journal of Biological Chemistry, Numéro 301, 2025, ISSN 0021-9258
Éditeur: Elsevier BV
DOI: 10.1016/J.JBC.2025.108332

4′-Fluorouridine inhibits alphavirus replication and infection <i>in vitro</i> and <i>in vivo</i>

Auteurs: Peiqi Yin, Nicholas A. May, Laura Sandra Lello, Atef Fayed, M. Guston Parks, Adam M. Drobish, Sainan Wang, Meghan Andrews, Zachary Sticher, Alexander A. Kolykhalov, Michael G. Natchus, George R. Painter, Andres Merits, Margaret Kielian, Thomas E. Morrison
Publié dans: mBio, Numéro 15, 2024, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/MBIO.00420-24

Dengue Virus Inhibitors as Potential Broad-Spectrum Flavivirus Inhibitors

Auteurs: Larisa Ivanova, Krystyna Naumenko, Margus Varjak, Sandra Koit, Yehudit Morozovsky, Andres Merits, Mati Karelson, Eva Zusinaite
Publié dans: Pharmaceuticals, Numéro 18, 2025, ISSN 1424-8247
Éditeur: MDPI AG
DOI: 10.3390/PH18030283

Genome-wide association study reveals 18 QTL for major agronomic traits in a Nordic–Baltic spring wheat germplasm

Auteurs: Andrius Aleliūnas, Andrii Gorash, Rita Armonienė, Ilmar Tamm, Anne Ingver, Māra Bleidere, Valentīna Fetere, Hannes Kollist, Tomasz Mroz, Morten Lillemo, Gintaras Brazauskas
Publié dans: Frontiers in Plant Science, Numéro 15, 2024, ISSN 1664-462X
Éditeur: Frontiers Media SA
DOI: 10.3389/FPLS.2024.1393170

Boosting photosynthesis opens new opportunities for agriculture sustainability and circular economy: The <scp>BEST</scp>‐<scp>CROP</scp> research and innovation action

Auteurs: Paolo Pesaresi, Pierre Bono, Stephane Corn, Cristina Crosatti, Sara Daniotti, Jens Due Jensen, Ivo Frébort, Eder Groli, Claire Halpin, Mats Hansson, Goetz Hensel, David S. Horner, Kelly Houston, Ahmed Jahoor, Miloš Klíma, Hannes Kollist, Clément Lacoste, Boubker Laidoudi, Susanna Larocca, Caterina Marè, Nicolas Le Moigne, Chiara Mizzotti, Tomas Morosinotto, Klaus Oldach, Laura Rossini, Sebastian Raubach, Miguel Sanchez‐Garcia, Paul D. Shaw, Rodolphe Sonnier, Alessandro Tondelli, Robbie Waugh, Andreas P.M. Weber, Dmitry Yarmolinsky, Alessandro Zeni, Luigi Cattivelli
Publié dans: The Plant Journal, Numéro 121, 2025, ISSN 0960-7412
Éditeur: Wiley
DOI: 10.1111/TPJ.17264

A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants

Auteurs: Xiang Liu, Wern Hann Ng, Eva Zusinaite, Joseph Freitas, Adam Taylor, Venugopal Yerragunta, Shukra Madhaha Aavula, Sambaiah Gorriparthi, Santhakumar Ponsekaran, Rama Lakshmi Bonda, Priyanka Mani, Sridevi V. Nimmagadda, Sainan Wang, Laura Sandra Lello, Ali Zaid, Ujjwal Dua, Sharon A. Taft-Benz, Elizabeth Anderson, Victoria K. Baxter, Sanjay Sarkar, Zheng L. Ling, Thomas M. Ashhurst, Samuel M. S. Cheng, Priyabrata Pattnaik, Anand Kumar Kanakasapapathy, Ralph S. Baric, Felicity J. Burt, Malik Peiris, Mark T. Heise, Nicholas J. C. King, Andres Merits, Rajendra Lingala, Suresh Mahalingam
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-51535-Y

Exploring the potential of microbial biomass and microbial extracted oils in tribology: a sustainable frontier for environmentally acceptable lubricants

Auteurs: Szymon Bernat, Francesca Di Bartolomeo, Sergio Armada, Emil Valaker, Nemailla Bonturi, Deni Koseto, Tone Haugen, Ann-Karin Kvernbråten, Petr Stavárek, Marek Večeř, Ladislav Zelenka
Publié dans: Green Chemistry Letters and Reviews, Numéro 17, 2024, ISSN 1751-8253
Éditeur: Informa UK Limited
DOI: 10.1080/17518253.2024.2330644

The Synthetic Peptide GA-Hecate and Its Analogs Inhibit Multiple Steps of the Chikungunya Virus Infection Cycle In Vitro

Auteurs: Gabriela Miranda Ayusso, Paulo Ricardo da Silva Sanches, Tamara Carvalho, Igor Andrade Santos, Daniel Oliveira Silva Martins, Maria Letícia Duarte Lima, Pâmela Jóyce Previdelli da Conceição, Cíntia Bittar, Andres Merits, Eduardo Maffud Cilli, Ana Carolina Gomes Jardim, Paula Rahal, Marilia Freitas Calmon
Publié dans: Pharmaceuticals, Numéro 16, 2025, ISSN 1424-8247
Éditeur: MDPI AG
DOI: 10.3390/PH16101389

SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs

Auteurs: Siwen Long, Mykhailo Guzyk, Laura Perez Vidakovics, Xiao Han, Renhua Sun, Megan Wang, Marc D. Panas, Egon Urgard, Jonathan M. Coquet, Andres Merits, Adnane Achour, Gerald M. McInerney
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-54996-3

PanKB: An interactive microbial pangenome knowledgebase for research, biotechnological innovation, and knowledge mining

Auteurs: Binhuan Sun, Liubov Pashkova, Pascal Aldo Pieters, Archana Sanjay Harke, Omkar Satyavan Mohite, Alberto Santos, Daniel C Zielinski, Bernhard O Palsson, Patrick Victor Phaneuf
Publié dans: Nucleic Acids Research, Numéro 53, 2025, ISSN 0305-1048
Éditeur: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAE1042

Phenotypic diversity of key adaptive traits in advanced Nordic and Baltic spring wheat (Triticum aestivum L.) breeding material

Auteurs: Anne Ingver, Andrii Gorash, Elena Ivandi, Vija Strazdina, Andrius Aleliūnas, Tanel Kaart, Valentina Fetere, Egon Meigas, Zaiga Jansone, Sahameh Shafiee, Tomasz Mroz, Mara Bleidere, Ebe Merilo, Morten Lillemo, Hannes Kollist, Gintaras Brazauskas, Ilmar Tamm
Publié dans: Euphytica, Numéro 220, 2024, ISSN 0014-2336
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S10681-024-03404-4

Validation of flavivirus infectious clones carrying fluorescent markers for antiviral drug screening and replication studies

Auteurs: Liubov Cherkashchenko, Nathalie Gros, Alice Trausch, Aymeric Neyret, Mathilde Hénaut, Gregor Dubois, Matthieu Villeneuve, Christine Chable-Bessia, Sébastien Lyonnais, Andres Merits, Delphine Muriaux
Publié dans: Frontiers in Microbiology, Numéro 14, 2023, ISSN 1664-302X
Éditeur: Frontiers Media SA
DOI: 10.3389/FMICB.2023.1201640

CDK signaling via nonconventional CDK phosphorylation sites

Auteurs: Ervin Valk, Mihkel Örd, Ilona Faustova, Mart Loog
Publié dans: Molecular Biology of the Cell, Numéro 34, 2023, ISSN 1059-1524
Éditeur: American Society for Cell Biology (ASCB)
DOI: 10.1091/MBC.E22-06-0196

LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy

Auteurs: Ningning Wang, Andres Merits, Michael Veit, Laura Sandra Lello, Shuhan Kong, Houqi Jiao, Jie Chen, Yu Wang, Georgi Dobrikov, Félix A. Rey, Shuo Su
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-49301-1

Constitutive activation of ABA receptors in Arabidopsis reveals unique regulatory circuitries

Auteurs: Oded Pri‐Tal, Yufei Sun, Armin Dadras, Janine M. R. Fürst‐Jansen, Gil Zimran, Daphna Michaeli, Akila Wijerathna‐Yapa, Michal Shpilman, Ebe Merilo, Dmitry Yarmolinsky, Idan Efroni, Jan de Vries, Hannes Kollist, Assaf Mosquna
Publié dans: New Phytologist, Numéro 241, 2025, ISSN 0028-646X
Éditeur: Wiley
DOI: 10.1111/NPH.19363

Stomatal CO ₂ /bicarbonate sensor consists of two interacting protein kinases, Raf-like HT1 and non-kinase-activity requiring MPK12/MPK4

Auteurs: Yohei Takahashi, Krystal C. Bosmans, Po-Kai Hsu, Karnelia Paul, Christian Seitz, Chung-Yueh Yeh, Yuh-Shuh Wang, Dmitry Yarmolinsky, Maija Sierla, Triin Vahisalu, Cezary Waszczak, J. Andrew McCammon, Jaakko Kangasjärvi, Li Zhang, Hannes Kollist, Thien Trac, Julian I. Schroeder
Publié dans: Science Advances, Numéro 8, 2024, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ABQ6161

Adaptive laboratory evolution of <i>Clostridium autoethanogenum</i> to metabolize CO₂ and H₂ enhances growth rates in chemostat and unravels proteome and metabolome alterations

Auteurs: James Heffernan, R. Axayactl Garcia Gonzalez, Vishnu Mahamkali, Tim McCubbin, Dara Daygon, Lian Liu, Robin Palfreyman, Audrey Harris, Michael Koepke, Kaspar Valgepea, Lars Keld Nielsen, Esteban Marcellin
Publié dans: Microbial Biotechnology, Numéro 17, 2024, ISSN 1751-7915
Éditeur: Wiley
DOI: 10.1111/1751-7915.14452

Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study

Auteurs: Erlend Ravlo, Aleksandr Ianevski, Eirin Starheim, Wei Wang, Ping Ji, Hilde Lysvand, Teemu Smura, Gaily Kivi, Maia-Liisa Voolaid, Kati Plaan, Mart Ustav, Mart Ustav, Eva Zusinaite, Tanel Tenson, Reet Kurg, Valentyn Oksenych, Kirsti Walstad, Svein Arne Nordbø, Mari Kaarbø, Karin Ernits, Magnar Bjørås, Denis E. Kainov, Mona Høysæter Fenstad
Publié dans: International Journal of Infectious Diseases, Numéro 137, 2024, ISSN 1201-9712
Éditeur: Elsevier BV
DOI: 10.1016/J.IJID.2023.10.011

Evidence of Differences in Cellular Regulation of Wolbachia-Mediated Viral Inhibition between Alphaviruses and Flaviviruses

Auteurs: Stephanie M. Rainey, Daniella A. Lefteri, Christie Darby, Alain Kohl, Andres Merits, Steven P. Sinkins
Publié dans: Viruses, Numéro 16, 2024, ISSN 1999-4915
Éditeur: MDPI AG
DOI: 10.3390/V16010115

Translational control of <i>MPS1</i> links protein synthesis with the initiation of cell division and spindle pole body duplication in <i>Saccharomyces cerevisiae</i>

Auteurs: Heidi M Blank, Annabel Alonso, Amy S Fabritius, Ervin Valk, Mart Loog, Mark Winey, Michael Polymenis
Publié dans: GENETICS, Numéro 227, 2025, ISSN 1943-2631
Éditeur: Oxford University Press (OUP)
DOI: 10.1093/GENETICS/IYAE069

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Auteurs: Nazgul Sakenova, Elisabetta Cacace, Askarbek Orakov, Florian Huber, Vallo Varik, George Kritikos, Jan Michiels, Peer Bork, Pascale Cossart, Camille V. Goemans, Athanasios Typas
Publié dans: Nature Microbiology, Numéro 10, 2025, ISSN 2058-5276
Éditeur: Springer Science and Business Media LLC
DOI: 10.1038/S41564-024-01857-W

Correction to: Phenotypic diversity of key adaptive traits in advanced Nordic and Baltic spring wheat (Triticum aestivum L.) breeding material

Auteurs: Anne Ingver, Andrii Gorash, Elena Ivandi, Vija Strazdina, Andrius Aleliūnas, Tanel Kaart, Valentina Fetere, Egon Meigas, Zaiga Jansone, Sahameh Shafiee, Tomasz Mroz, Mara Bleidere, Ebe Merilo, Morten Lillemo, Hannes Kollist, Gintaras Brazauskas, Ilmar Tamm
Publié dans: Euphytica, Numéro 220, 2024, ISSN 0014-2336
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S10681-024-03412-4

Kaurenoic acid is a potent inhibitor of SARS-CoV-2 RNA synthesis, virion assembly, and release in vitro

Auteurs: Igor Andrade Santos, Victoria Riquena Grosche, Natasha Marques Cassani, Rodrigo Cássio Sola Veneziani, Gustavo Lima Ribeiro, Jairo Kenupp Bastos, Nilson Nicolau-Junior, Andres Merits, Carlos Henrique Gomes Martins, Mark Harris, Ana Carolina Gomes Jardim
Publié dans: Frontiers in Microbiology, Numéro 16, 2025, ISSN 1664-302X
Éditeur: Frontiers Media SA
DOI: 10.3389/FMICB.2025.1540934

Enhanced and copper concentration dependent virucidal effect against SARS-CoV-2 of electrospun poly(vinylidene difluoride) filter materials

Auteurs: Hanna Bulgarin, Thomas Thomberg, Andres Lust, Jaak Nerut, Miriam Koppel, Tavo Romann, Rasmus Palm, Martin Månsson, Marko Vana, Heikki Junninen, Marian Külaviir, Päärn Paiste, Kalle Kirsimäe, Marite Punapart, Liane Viru, Andres Merits, Enn Lust
Publié dans: iScience, Numéro 27, 2025, ISSN 2589-0042
Éditeur: Elsevier BV
DOI: 10.1016/J.ISCI.2024.109835

Characterization of duck tembusu virus NS2A membrane topology and functional residues in transmembrane domain-3 on viral proliferation

Auteurs: Wei Zhang, Miao Zeng, Bowen Jiang, Yao Cheng, Yu He, Zhen Wu, Tao Wang, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Di Sun, Andres Merits, Anchun Cheng, Shun Chen
Publié dans: Poultry Science, Numéro 103, 2025, ISSN 0032-5791
Éditeur: Elsevier BV
DOI: 10.1016/J.PSJ.2024.104423

Genome-wide association analysis identifies a consistent QTL for powdery mildew resistance on chromosome 3A in Nordic and Baltic spring wheat

Auteurs: Min Lin, Bulat Islamov, Andrius Aleliūnas, Rita Armonienė, Andrii Gorash, Egon Meigas, Anne Ingver, Ilmar Tamm, Hannes Kollist, Vija Strazdiņa, Māra Bleidere, Gintaras Brazauskas, Morten Lillemo
Publié dans: Theoretical and Applied Genetics, Numéro 137, 2024, ISSN 0040-5752
Éditeur: Springer Science and Business Media LLC
DOI: 10.1007/S00122-023-04529-1

Low electric current in a bioelectrochemical system facilitates ethanol production from CO using CO-enriched mixed culture

Auteurs: Chaeho Im, Minsoo Kim, Jung Rae Kim, Kaspar Valgepea, Oskar Modin, Yvonne Nygård, Carl Johan Franzén
Publié dans: Frontiers in Microbiology, Numéro 15, 2024, ISSN 1664-302X
Éditeur: Frontiers Media SA
DOI: 10.3389/FMICB.2024.1438758

Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine

Auteurs: Peiqi Yin, Elizabeth B. Sobolik, Nicholas A. May, Sainan Wang, Atef Fayed, Dariia Vyshenska, Adam M. Drobish, M. Guston Parks, Laura Sandra Lello, Andres Merits, Thomas E. Morrison, Alexander L. Greninger, Margaret Kielian
Publié dans: PLOS Pathogens, Numéro 21, 2025, ISSN 1553-7374
Éditeur: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PPAT.1012859

The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants

Auteurs: Aleksandr Ianevski, Irene Trøen Frøysa, Hilde Lysvand, Carlemi Calitz, Teemu Smura, Hans-Johnny Schjelderup Nilsen, Erling Høyer, Jan Egil Afset, Adithya Sridhar, Katja C. Wolthers, Eva Zusinaite, Tanel Tenson, Reet Kurg, Valentyn Oksenych, Angel S. Galabov, Adelina Stoyanova, Magnar Bjørås, Denis E. Kainov
Publié dans: Antiviral Research, Numéro 224, 2024, ISSN 0166-3542
Éditeur: Elsevier BV
DOI: 10.1016/J.ANTIVIRAL.2024.105842

Attenuated Getah virus confers protection against multiple arthritogenic alphaviruses

Auteurs: Zhiwen Jiang, Andres Merits, Ying Qin, Gang Xing, Letian Zhang, Jie Chen, Ningning Wang, Margus Varjak, Xiaofeng Zhai, Dongyan Li, Wanjie Song, Shuo Su
Publié dans: PLOS Pathogens, Numéro 20, 2024, ISSN 1553-7374
Éditeur: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PPAT.1012700