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Strengthening the European Chain of sUpply for next generation medical RadionuclidEs

Objective

SECURE project aims to make a major contribution to the sustainability of medical isotope production and its safe application in Europe. It is focusing on promising developments in the design of irradiation targets, production routes for existing and new isotopes in nuclear therapy and diagnostics. Isotopes critical in the success of nuclear medicine are selected and research activities are identified to address some of the major challenges in securing its future availability, with the objectives: 1. to remove critical barriers along the production of its selected alpha and beta emitting isotopes that restrict a sustainable production, 2. to develop a framework of guidance and recommendations that enables exploring the full clinical potential of alpha and beta particle therapy and its safe application 3. to provide important lessons learned that act as a demonstration case for addressing issues in upscaling and sustained isotope production. At present, Ra-223 is the only radiopharmaceutical which has been granted marketing authorization to treat adults with prostate cancer. This has paved the way for a wider use of other alpha emitters such as Ac-225 or Bi-213. The expected demand of nuclear medicine for novel alpha emitters and beta- emitters requires re-evaluation of their production methods and inventories of target materials and parent radionuclides. The ambition of SECURE consortium is to identify and efficiently use the current resources for new radionuclides, in particular for alpha emitters and the relevant beta emitting theranostic radionuclides. The development of alternative technologies for production of such therapeutic radionuclides for improved patient treatment requires multidisciplinary scientific and technological knowledge including physics, chemistry, material science, machining of target materials, chemistry, biology and radiobiology, radiopharmacy and nuclear medicine. All this chain of expertise is present in SECURE consortium.

Coordinator

NARODOWE CENTRUM BADAN JADROWYCH
Net EU contribution
€ 296 937,50
Other funding
€ 0,00

Participants (16)

NUCLEAR RESEARCH AND CONSULTANCY GROUP
Netherlands
Net EU contribution
€ 584 803,75
Address
Westerduinweg 3
1755 LE Petten

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Region
West-Nederland Noord-Holland Kop van Noord-Holland
Activity type
Other
Other funding
€ 0,00
INSTITUT MAX VON LAUE - PAUL LANGEVIN
France
Net EU contribution
€ 336 665,00
Address
71 Avenue Des Martyrs
38000 Grenoble

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Region
Auvergne-Rhône-Alpes Rhône-Alpes Isère
Activity type
Research Organisations
Other funding
€ 0,00
INSTITUT JOZEF STEFAN
Slovenia
Net EU contribution
€ 234 875,00
Address
Jamova 39
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Research Organisations
Other funding
€ 0,00
EUROPEAN NUCLEAR EDUCATION NETWORK
Belgium
Net EU contribution
€ 150 625,00
Address
Egmontstraat 11
1000 Brussel

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Research Organisations
Other funding
€ 0,00
ENERGIATUDOMANYI KUTATOKOZPONT
Hungary
Net EU contribution
€ 126 250,00
Address
Konkoly Thege Miklos Ut 29-33
1121 Budapest

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Region
Közép-Magyarország Budapest Budapest
Activity type
Research Organisations
Other funding
€ 0,00
EUROPEAN FEDERATION OF ORGANISATIONS FOR MEDICAL PHYSICS
Netherlands
Net EU contribution
€ 123 750,00
Address
Mercatorlaan 1200
3528 BL Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Other
Other funding
€ 0,00
AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE
Italy
Net EU contribution
€ 370 718,75
Address
Lungotevere Grande Ammiraglio Thaon Di Revel 76
00196 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Other funding
€ 0,00
STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE
Belgium
Net EU contribution
€ 394 238,00
Address
Avenue Herrmann Debroux 40
1160 Bruxelles

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Research Organisations
Other funding
€ 1 749,50
EVALION SRO
Czechia
Net EU contribution
€ 125 000,00
Address
Na Berance 57/2
16000 Praha

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Praha Hlavní město Praha
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM
Hungary
Net EU contribution
€ 87 187,50
Address
Muegyetem Rakpart 3
1111 Budapest

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Region
Közép-Magyarország Budapest Budapest
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
CLUST ER INDUSTRIE DELLA SALUTE E DEL BENESSERE
Italy
Net EU contribution
€ 51 250,00
Address
Via P Gobetti 101
40129 Bologna

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Emilia-Romagna Bologna
Activity type
Other
Other funding
€ 0,00
CLUSTERUL REGIONAL INOVATIV DE IMAGISTICA MOLECULARA SI STRUCTURALA NORD-EST (IMAGO-MOL)
Romania
Net EU contribution
€ 61 000,00
Address
16 Universitatii St Building A1 Ground Floor
700115 Iasi

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Region
Macroregiunea Doi Nord-Est Iaşi
Activity type
Research Organisations
Other funding
€ 0,00
ISTITUTO ROMAGNOLO PER LO STUDIO DEI TUMORI DINO AMADORI - IRST SRL
Italy
Net EU contribution
€ 307 500,00
Address
Via Maroncelli 40
47014 Meldola

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Region
Nord-Est Emilia-Romagna Forlì-Cesena
Activity type
Research Organisations
Other funding
€ 0,00
UNIVERSITE DE BRETAGNE OCCIDENTALE
France
Net EU contribution
€ 282 500,00
Address
Rue Des Archives 3
29238 Brest

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Region
Bretagne Bretagne Finistère
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERZITETNI KLINICNI CENTER LJUBLJANA
Slovenia
Net EU contribution
€ 97 125,00
Address
Zaloska Cesta 002
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION
Belgium
Net EU contribution
€ 0,00
Address
Rue De La Loi 200
1049 Brussels

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Research Organisations
Other funding
€ 25 000,00

Partners (1)

NATIONAL NUCLEAR LABORATORY LIMITED
United Kingdom
Net EU contribution
€ 0,00
Address
Chadwick House Warrington Road
WA3 6AE Warrington

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Region
North West (England) Cheshire Warrington
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data