Objective
To conquer land, vascular plants evolved a sophisticated root system, which consists of primary and lateral roots (LRs). The de novo LR organogenesis represents a major evolutionary innovation, which has provided sessile organisms like plants with the capacity to forage for water and nutrients. The host lab is a pioneer in demonstrating that LR formation requires de novo specification of stem cells inside the primary root. They also discovered that the early stages of LR initiation are regulated by an oscillatory mechanism where the phytohormone auxin plays a major role. Despite these advances, the exact molecular mechanisms underlying lateral root stem cell (LRSC) specification remain largely elusive and it is not known how these mechanisms emerged during plant evolution. To address these fundamental questions, I will use an emerging model system Ceratopteris richardii (C-fern), which is an evolutionary pivotal, yet underexplored model plant. Based on fossil records, ferns and seed plants diverged during the middle Devonian period from a common ancestor suggesting that several key regulators might be conserved among them, despite some differences in their root ontogeny. In C-fern, the formation of LRSCs is clearly visible at the anatomic level. C-fern has ancestral and possibly simpler mechanisms underlying LRSC specification. In this project, I aim to identify key transcription factors controlling LRSC specification in C-fern. To achieve this goal, I will combine my expertise in molecular and developmental biology with multidisciplinary approaches including single cell RNA sequencing, CRISPR/Cas9-based genome editing and top-notch confocal imaging. This project has a strong potential to introduce novel concepts in the field of plant stem cells and their evolution. It will also open new perspectives for me to become an independent researcher in the field of evo-devo of plant stem cells.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology cells technologies stem cells
- natural sciences biological sciences genetics RNA
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
9052 ZWIJNAARDE - GENT
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.