Objective
DrugCer proposes a paradigm shift in drug delivery for bone restoration by making drugs an inherent part of a biodegradable ceramic implant. Such a new approach would require drug loading during ceramic sintering, which in turn requires multidisciplinary research and development of low-temperature/cold ceramic processing. Accordingly, the main research goal of DrugCer is to apply a novel pressure-assisted “Cold Sintering Process” (CSP) for co-sintering of biodegradable ceramics with drugs. To achieve the goal, the researcher will receive advanced training in CSP and develop the co-sintering process by establishing a relationship between the processing parameters and properties of the resulting bioceramics. She will train in and master cryo-focused ion beam milling and cryo-scanning transmission electron microscopy to investigate the process kinetics and densification mechanisms. Finally, she will train in and develop methods for complex shaping to adapt the method for potential translation to preclinical studies. Cold-sintering will decrease energy consumption in bioceramics’ fabrication. It will also enable bioceramic co-sintering with other temperature-sensitive materials (e.g. polymers), opening paths to innovations in fields beyond orthopedics or even medicine (e.g. construction ceramics).
Multidisciplinary supervising teams at Fraunhofer IKTS (host) and Penn State University (secondment) will support training through research and transferrable skills development (grant writing, teaching/mentoring, project management, networking, and horizontal skills). Inter-sectoral communication with Charité hospital (short visits) will ensure high-quality guidance in developing prospective biomedical technology from its very beginning. Thus, DrugCer will equip the researcher with unique expertise, skills, and a professional network for establishing an independent group in the niche of low-temperature, energy-efficient ceramic processing.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences polymer sciences
- natural sciences physical sciences optics microscopy
- medical and health sciences medical biotechnology implants
- engineering and technology materials engineering ceramics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80686 MUNCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.