Experimental vaccinology, revealing unnatural signatures of protection by repeat controlled human schistosome infection.

Project Information

ReCHISVac

Grant agreement ID: 101063914

DOI

10.3030/101063914

Project closed

EC signature date 10 May 2022

Start date 1 June 2022

End date 30 November 2024

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 234 530,40

Coordinated by

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

Communication, Dissemination & Outreach Plan

The plan describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned, and the target group(s) addressed. Regarding communication measures and public engagement strategy, the aim is to inform and reach out to society and show the activities performed, and the use and the benefits the project will have for citizens.

Publications

Peer reviewed articles (3)

Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study

Author(s): Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg
Published in: eBioMedicine, Issue 97, 2023, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104832

Pre-clinical studies of Schistosoma mansoni vaccines: A scoping review

Author(s): Emma L. Houlder, Lucas Ferreira da Silva, Angela van Diepen, Murilo Sena Amaral, R. Alan Wilson, Cornelis H. Hokke, Meta Roestenberg, Wilfried A.M. Bakker
Published in: PLOS Neglected Tropical Diseases, Issue 19, 2025, ISSN 1935-2735
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PNTD.0012956

Early symptom-associated inflammatory responses shift to type 2 responses in controlled human schistosome infection

Author(s): Emma L. Houlder, Koen A. Stam, Jan Pieter R. Koopman, Marion H. König, Marijke C. C. Langenberg, Marie-Astrid Hoogerwerf, Paula Niewold, Friederike Sonnet, Jacqueline J. Janse, Miriam Casacuberta Partal, Jeroen C. Sijtsma, Laura H. M. de Bes-Roeleveld, Yvonne C. M. Kruize, Maria Yazdanbakhsh, Meta Roestenberg
Published in: Science Immunology, Issue 9, 2024, ISSN 2470-9468
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciimmunol.adl1965