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MicrobiomE-associaTEd boosters Of immune Responses (METEOR study): experimental charac-terization and clinical exploitation.

Project description

Microbiome-associated modulators of immune response

The interactions between host cells and bacteria by-products can affect their metabolism, modifying the outcome of the disease. Funded by the Marie Skłodowska-Curie Actions programme, the METEOR study project aims to develop experimental strategies to identify new therapeutic agents, using microbiome-associated boosters of immune responses to infection. The research will employ directed culturomics, immune stimulations assays, and multi-omics toolbox to characterise functional immune profiles associated with protective immune responses and implement data-mining via a bioinformatics integration approach. The objective is to investigate gut microbiota from different compartments and microbial communities from disease-related tissues. The selected specific candidates will be validated in preclinical and clinical studies as therapeutic agents for the improvement of disease-specific immune responses.

Coordinator

FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO RAMON Y CAJAL
Net EU contribution
€ 192 865,12
Address
Ctra Colmenar Vlejo Km 9.100
28034 Madrid
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Other
Other funding
No data

Partners (2)

Mikrobiomik Healthcare Company
Spain
Net EU contribution
€ 0,00
Address
Astondo Bidea, 612
48160 Derio

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Region
Noreste País Vasco Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
No data
University of Colorado Denver
United States
Net EU contribution
€ 0,00
Other funding
No data