Atomic force microscopy-based exploration of layered double hydroxide nanoparticles adjuvant mechanism

Project Information

AFM-LDH

Grant agreement ID: 101064861

DOI

10.3030/101064861

EC signature date 1 August 2022

Start date 1 September 2023

End date 31 January 2026

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 230 774,40

Coordinated by

AARHUS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cycle for all data sets that will be collected, processed or generated by the action. It is a document describing what data will be collected, processed or generated and following what methodology and standards, whether and how this data will be shared and/or made open, and how it will be curated and preserved.

Publications

Peer reviewed articles (13)

Precise CAR-T cell therapy targeting non-cancerous diseases: Advances in precision medicine and bioengineering

Author(s): Chaojie Zhu, Feifan Wang, Zesheng Cheng, Lingxiao Zhang, Hongjun Li
Published in: Precision Medicine and Engineering, Issue 2, 2025, ISSN 2950-4821
Publisher: Elsevier BV
DOI: 10.1016/J.PREME.2025.100024

pH of Microenvironment Directly Modulates the Phenotype and Function of Cancer-Associated Fibroblasts

Author(s): Ying Li, Chao He, Ai Ning Shen, Yu Wang, Zhi Ping Xu, Lingxiao Zhang, Ran Wang
Published in: ACS Omega, Issue 10, 2025, ISSN 2470-1343
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSOMEGA.4C09716

An Immunomodulatory Zinc-Alum/Ovalbumin Nanovaccine Boosts Cancer Metalloimmunotherapy Through Erythrocyte-Assisted Cascade Immune Activation

Author(s): Jing Zhao, Lingxiao Zhang, Pin Li, Shanbiao Liu, Shiyi Yu, Zheng Chen, Mingjian Zhu, Shangzhi Xie, Daishun Ling, Fangyuan Li
Published in: Advanced Science, Issue 11(6): 2307389, 2024, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202307389

Interleukin 12-tethered nano-aluminum adjuvant orchestrates environmental immunomodulation to empower cytotoxic T cells against solid tumors

Author(s): Aining Shen, Jing Zhao, Zhenwei Su, Ran Wang, Ying Li, Chaojie Zhu, Qingyuan Zhao, Pinwan Yu, Zhi Ping Xu, Lingxiao Zhang
Published in: Acta Pharmaceutica Sinica B, 2025, ISSN 2211-3835
Publisher: Elsevier BV
DOI: 10.1016/J.APSB.2025.10.021

Engineered nano-aluminum adjuvant for cancer immunotherapy: Progress, challenges and opportunities towards preclinical/clinical application

Author(s): Chong Gao, Jianping Jiang, Jing Zhao, Zhi Ping Xu, Lingxiao Zhang
Published in: Coordination Chemistry Reviews, Issue 519, 2024, ISSN 0010-8545
Publisher: Elsevier BV
DOI: 10.1016/j.ccr.2024.216109

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Author(s): Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang
Published in: Advanced Functional Materials, 2025, ISSN 1616-301X
Publisher: Wiley
DOI: 10.1002/ADFM.202502801

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Author(s): Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang
Published in: Advanced Functional Materials, Issue 35, 2025, ISSN 1616-301X
Publisher: Wiley
DOI: 10.1002/ADFM.202502801

Biomimetic-smart materials for osteochondral regeneration and repair

Author(s): Qi-Peng Jia, Qunfeng Li, Hamza Boucetta, Zhi-Ping Xu, Ling-Xiao Zhang
Published in: Microstructures, Issue 4, 2024, ISSN 2770-2995
Publisher: OAE Publishing Inc.
DOI: 10.20517/microstructures.2023.84

Next-generation aluminum adjuvants: Immunomodulatory layered double hydroxide NanoAlum reengineered from first-line drugs

Author(s): Zhenwei Su, Hamza Boucetta, Jiahui Shao, Jinling Huang, Ran Wang, Aining Shen, Wei He, Zhi Ping Xu, Lingxiao Zhang
Published in: Acta Pharmaceutica Sinica B, Issue 14, 2024, ISSN 2211-3835
Publisher: Elsevier BV
DOI: 10.1016/J.APSB.2024.09.012

Advanced Functional Materials

Author(s): Lingxiao Zhang, Chaojie Zhu, Jing Zhao, Luca Scimeca, Mingdong Dong, Ruitian Liu, Yingbo Jia, Zhi Ping Xu
Published in: Advanced Functional Materials, Issue 2311914, 2024, ISSN 1616-301X
Publisher: Wiley
DOI: 10.1002/adfm.202311914

Artificially tagging tumors with nano-aluminum adjuvant-tethered antigen mRNA recruits and activates antigen-specific cytotoxic T cells for enhanced cancer immunotherapy

Author(s): Lingxiao Zhang, Jie Bai, Aining Shen, Jing Zhao, Zhenwei Su, Maoze Wang, Mingdong Dong, Zhi Ping Xu
Published in: Biomaterials, Issue 317, 2025, ISSN 0142-9612
Publisher: Elsevier BV
DOI: 10.1016/J.BIOMATERIALS.2025.123085

Advancing cancer gene therapy: the emerging role of nanoparticle delivery systems

Author(s): Maoze Wang, Huina Liu, Jinling Huang, Ting Cai, Zhi Ping Xu, Lingxiao Zhang
Published in: Journal of Nanobiotechnology, Issue 23, 2025, ISSN 1477-3155
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12951-025-03433-8

Biomimetic selenium nanomedicine with homologous targeting enhances hepatocellular carcinoma therapy

Author(s): Fang Cui, Qi-xin Huang, Zhuo Yu, Jin-ju Yang, Shi-yu Liang, Mei-qi Wang, Jie Zhu, Chen Tian, Shao-xun Li, Hao-tian Wang, Fei Chen, Yang-jie Li, Xiaobin Feng, Rui-tian Liu, Lingxiao Zhang
Published in: Materials Today Bio, Issue 35, 2025, ISSN 2590-0064
Publisher: Elsevier BV
DOI: 10.1016/J.MTBIO.2025.102441