Objective
Sailors called it burning of the sea, Shakespeare described it as pale fire and Aristotle named it cold light. The glimmer they witnessed was light emitted by living organisms or bioluminescence. While it represents one of the most striking examples of convergent evolution across the tree of life, in Fungi it has a single origin in the Agaricales order, Basidiomycota. In particular, Mycena, a large genus of mushroom-forming fungi, includes most of known bioluminescent species together with hundreds of species that lost the ability to emit light. In GLiMMer, I will study the evolution of fungal bioluminescence and test the hypothesis that multiple, lineage-specific mechanisms led to the convergent loss of this trait, providing clues for its ecological relevance. To date, Mycena lacks a robust phylogenetic framework and is heavily under sampled. Fungarium collections, such as the one at Naturalis, preserved thousands of Mycena specimens over the past centuries. Thanks to new high-throughput sequencing methods these collections are being transformed in genomics resources, bridging taxonomy and evolution. In GLiMMer, my expertise in fungal genomics will serve to develop a genome-based classification of Mycena, that combines contemporary and museum specimens. I will generate assemblies of 100 representative species using short-read sequencing. Next, I will extract phylogenetically informative loci to design a target sequence capture method for recalcitrant museum specimens for the first time in mushrooms. Then, I will use the new classification to select reference species and obtain chromosomal-level assemblies using long-read sequencing. Finally, with genome-wide synteny analyses I will investigate the evolutionary circumstances that led to the birth and death of bioluminescence in Fungi. By integrating taxonomy, genomics and evolution, my project will create a paradigm shift in our knowledge on fungal biodiversity and ultimately contribute to its conservation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences microbiology mycology
- humanities arts performing arts dramaturgy
- natural sciences biological sciences ecology ecosystems
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2021-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2333 CR Leiden
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.