Objective Brewer’s spent grain (BSG) is an agro-industrial by-product produced from breweries (~20 kg BSG/hlbeer). Its annual global production is estimated to be 39 million tons, with 3.4 million tons produced in the European Union. Most BSG is currently used as a low-value animal feed (35€/ton). In this context, BSG represents a promising feedstock for the production of novel added-value biomolecules. Indeed, this lignocellulosic material is composed of polyphenolic macromolecules such as ferulic (FA) and p-coumaric acids (PA), which have very important physiological functions and a market price of ~ 4000 €/Kg. BiOBreW will design novel recombinant enzymes that will allow obtaining high yields of FA and PA extraction from BSG. In addition, the widespread application of FA and PA in pharmaceutical industry is nowadays limited by their low permeability and instability. BiOBreW will overcome this limitation via innovative nano-encapsulation into nanocarriers (biocompatible and biodegradable selective polymers). The pretreated biomass obtained after the enzymatic extraction of FA and PA represents an ideal substrate for biogas production. However, electricity production from biogas will soon became economically non-feasible due to the rapid decrease in the prices of solar or wind power. In this context, the biological conversion of the methane contained in biogas into high added value products represents a novel and cost-competitive platform for biogas valorization. Halotolerant bacteria such as Methylomicrobium alkaliphilum can efficiently synthesize ectoine, one of the most valuable microbial protective compounds (market price ~ € 1,300/kg) using CH4 as the sole carbon and energy source. BiOBreW aims at enriching new high-yield ectoine producing strains and developing a new generation of high mass transfer bioreactors. BiOBreW will upgrade BSG using innovative biotechnologies and help creating new value chains in the context of circular economy in the brewery sector. Fields of science engineering and technologyenvironmental biotechnologybioremediationbioreactorsagricultural sciencesagriculture, forestry, and fisheriesagriculturegrains and oilseedsengineering and technologyenvironmental engineeringenergy and fuelsrenewable energywind powersocial scienceseconomics and businesseconomicssustainable economyagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandryanimal feed Programme(s) HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme Topic(s) HORIZON-MSCA-2021-PF-01-01 - MSCA Postdoctoral Fellowships 2021 Call for proposal HORIZON-MSCA-2021-PF-01 See other projects for this call Funding Scheme HORIZON-AG-UN - HORIZON Unit Grant Coordinator UNIVERSIDAD DE VALLADOLID Net EU contribution € 165 312,96 Address Plaza santa cruz 8 palacio de santa cruz 47002 Valladolid Spain See on map Region Centro (ES) Castilla y León Valladolid Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data Partners (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all DANMARKS TEKNISKE UNIVERSITET Denmark Net EU contribution € 0,00 Address Anker engelunds vej 101 2800 Kongens lyngby See on map Region Danmark Hovedstaden Københavns omegn Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data Compañia Cervecera de Canarias SA Spain Net EU contribution € 0,00 Address Calle mali, 7 38320 Santa cruz de tenerife See on map Region Canarias Canarias Tenerife Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data
