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On-Antenna Multi-Analyte Biochemical Sensing (ASense)

Descripción del proyecto

Una antena inalámbrica y de detección de doble función revolucionaria para dispositivos de laboratorio en chip

Las aplicaciones de los dispositivos inalámbricos de laboratorio en chip con matrices miniaturizadas de sensores bioquímicos conectados a transceptores de radio de baja potencia incluyen, por ejemplo, la seguridad alimentaria, la vigilancia ambiental y diagnóstico inmediato. Los científicos buscan aumentar la miniaturización de estos dispositivos, mejorar su rendimiento, minimizar su consumo energético y reducir sus costes. En el proyecto Asense, que cuenta con el apoyo de las Acciones Marie Skłodowska-Curie, se examinará el uso secundario de la antena inalámbrica de laboratorio en chip para la detección de múltiples analitos. Su equipo empleará un polímero impreso molecular que consta de nanomateriales de detección de analitos específicos. El polímero se cultivará sobre una capa de nanomaterial de transducción bidimensional muy conductiva, que detectará cambios en las características de radiación de la antena causados por la unión. Reducirá de forma considerable la complejidad y los costes relacionados, lo que mejorará el despliegue a gran escala de los laboratorios en chip.

Objetivo

Lab-on-chip (LOC) devices are useful for manipulating, analyzing, and interacting with small samples in a wide range of applications. Wireless LOC devices have been developed for remote and distributed analysis purposes where wired measurements are not feasible or cost-effective. The devices consist of a miniaturized array of biochemical sensors connected to a low-power radio transceiver. The current trend in wireless LOC devices is to miniaturize the sizes, lower the power consumption, and increase the processor capacity while driving down costs which are rapidly approaching their practical and theoretical limits. These raise the need for a new design to support the future sustainability of these devices to facilitate the current and upcoming massive deployments for use in various applications. Triggered by this, the project explores the revolutionary secondary use of the wireless antenna for multi-analyte active sensing purposes by deploying case-tailored sensing nanomaterials on the antenna surfaces current spots with each targeting a specific analyte using a Molecular Imprinting Polymer (MIP) layer grown above a highly conductive 2D transduction nanomaterial layer. The idea is to move the complexity from the wireless LOC to the computation of the gateway station, where signal processing and machine learning techniques are employed to remotely sense the targeted analytes. This is done by detecting changes on the radiation characteristics of the antenna caused by the applied sensing materials. The idea of using the antenna as a multi-analyte active sensor is an absolute novelty. If successful, the approach will have a huge contribution in reducing the hardware complexity of standard wireless LOC devices by at least 50% (no need to sensor integrated circuits, microcontrollers, and their associated power consumption), resulting in more than doubling their battery lifetime due to less power consumption, making large-scale mass deployment economically feasible.

Coordinador

NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
Aportación neta de la UEn
€ 226 751,04
Dirección
HOGSKOLERINGEN 1
7491 Trondheim
Noruega

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Región
Norge Trøndelag Trøndelag
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
Sin datos